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Junyu Liang, Weiqian Chen and Jin Lin

chromatin remodeling, promoter inactivation by binding to basal transcription factors, activation of accessory protein, activation and transport of transcription factors, oligomerization of activator protein, and epigenetic repression of genes or gene clusters. [ 10 ] Accumulating evidence has shown that lncRNAs participate in the process of inflammation, aberrant proliferation, migration, invasion and apoptosis, [ 11 , 12 , 13 , 14 ] and their roles in autoimmune diseases, such as systemic lupus erythematosus (SLE), sjogren syndrome, RA, multiple sclerosis, have

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Nan Ge, Jinlong Hu, Siyu Sun, Enqiang Linghu, Zhendong Jin and Zhaoshen Li

of the PPs to 3 cm on imaging (mainly EUS or CT) within 3 months. Procedure-related side effects included hemorrhage, stent migration into the cyst, cyst rupture with the use of cystotome, and severe infection. Reinterventions are endoscopic treatments performed after the initial EUS-guided stent placement. Failures include residual clinical symptoms, cyst reduction less than 50% in 3 months, or altered to open surgery. Hospital stay is calculated from the day of the initial EUS-guided drainage in hospital to the day of discharge. Devices Longitudinal

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Sarah P. Georgiadou, Konstantinos P. Makaritsis and George N. Dalekos


Leishmaniasis is a vector-borne disease caused by protozoan parasites of the genus Leishmania. It is transmitted by phlebotomine female sand flies of the genera Phlebotomus and Lutzomyia in the old and new world, respectively. More than 20 well-recognized Leishmania species are known to infect humans and cause visceral (VL), cutaneous (CL) and mucocutaneous (ML) forms of the disease. Approximately 350 million people are at risk of contracting the disease and an estimated 1.6 million new cases occur annually. The disease mainly affects poor people in Africa, Asia and Latin America, and is associated with malnutrition, population migration, poor residency conditions, frail immune system and lack of resources. Previously, diagnosis of leishmaniasis relied mainly on invasive techniques of detecting parasites in splenic and bone marrow aspirates. Nevertheless, serological tests using the recombinant kinesin antigen (rK39) and molecular methods (polymerase chain reaction) are considered the best options for diagnosis today, despite problems related to varying sensitivities and specificities and field adaptability. Therapy of leishmaniasis ranges from local treatment of cutaneous lesions to systemic often toxic, therapy for disseminated CL, ML and VL. Agents with efficacy against leishmaniasis include amphotericin B, pentavalent antimonial drugs, paromomycin and miltefosine. No single therapy of VL currently offers satisfactory efficacy along with safety. This article provides a brief and updated systematic review on the epidemiology, diagnosis and treatment of this neglected disease.

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Adela-Gabriela Firănescu and Maria Moța

. Trop Med Int Health 21: 694-702, 2016. 11. Workneh MH, Bjune GA, Yimer SA. Prevalence and associated factors of tuberculosis and diabetes mellitus comorbidity: A systematic review. PLoS One 12: e0175925, 2017. 12. Lin YH, Chen CP, Chen PY et al. Screening for pulmonary tuberculosis in type 2 diabetes elderly: a cross-sectional study in a community hospital. BMC Public Health 15: 3, 2015. 13. Girardi E, Schepisi MS, Goletti D et al. The global dynamics of diabetes and tuberculosis: the impact of migration and policy implications. Int J

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Adela-Gabriela Firănescu, Adina Popa, Maria-Magdalena Roşu, Diana Cristina Protasiewicz, Simona Georgiana Popa, Mihai Ioana and Maria Moța

. Effect of diabetes mellitus on tuberculosis treatment outcome and adverse reactions in patients receiving directly observed treatment strategy in India: A prospective study. Biomed Res Int 2016: 7273935, 2016. 31. Caraffa E, Schepisi MS, Gualano G et al. The diabetes-tuberculosis co-epidemic: the role of international migration. Int J Tuberc Lung Dis 20: 771–777, 2016. 32. Lin YH, Chen CP, Chen PY et al. Screening for pulmonary tuberculosis in type 2 diabetes elderly: a cross-sectional study in a community hospital. BMC Public Health 15: 3, 2015

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Georgiana Enache, Emilia Rusu, Alexandra Ilinca, Florin Rusu, Adrian Costache and Gabriela Radulian

. Obesity and body size perceptions in a Spanish Roma population. Ann Hum Biol 41: 428-435, 2014. 25. Gualdi-Russo E , Zironi A , Dallari GV , Toselli S . Migration and health in Italy: a multiethnic adult sample. J Travel Med 16: 88-95, 2009. 26. Zeljko HM, Skarić-Jurić T, Narančić NS et al. Age trends in prevalence of cardiovascular risk factors in Roma minority population of Croatia. Econ Hum Biol 11: 326-336, 2012. 27. Carrasco-Garrido P , López de Andrés A , Hernández Barrera V , Jiménez-Trujillo I , Jiménez-García R . Health status of

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Eva Kiousi and Eirini Grapsa

, Fennell RS. Family behavior, adaptation and treatment adherence of nephrology patients. Pediatr Nephrol 1996;10:160-6. 26. Züllich D, Zimmering M, Keil T, Querfeld U. Migration background and patient satisfaction in a pediatric nephrology outpatient clinic. Pediatr Nephrol 2012;27:1309-16. 27. Davis JS, Zuber K. Implementing patient education in the CKD clinic. Adv Chronic Kidney Dis 2013;20:320-5. 28. Kutlugün AA, Arıcı M, Yıldırım T, Turgut D, Yılmaz R, Altındal M, et al. Daily sodium intake in chronic kidney disease

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Weili Men, Haijuan Xiao, Zhiping Yang and Daiming Fan

]. Prod Res 2011; 9: 7. Wang Y [Overview of talent agglomeration research] Prod Res 2011 9 7 2 Giannetti M. Skill complementarities and migration decisions. Labor 2001; 15: 1-32. 10.1111/1467-9914.00153 Giannetti M Skill complementarities and migration decisions Labor 2001 15 1 32 3 Kalling T. Knowledge management and the occasional links with performance. J Knowl Manag 2003; 3: 67-81. Kalling T Knowledge management and the occasional links with performance J Knowl Manag 2003 3 67 81 4 Cohen WM, Nelson RR, Walsh JP. Links

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Xue Peng, Can Wei, Hong-Zhu Li, Hong-Xia Li, Shu-Zhi Bai, Li-Na Wang, Yu-Hui Xi, Jin Yan and Chang-Qing Xu

to the proliferation of PASMCs and vascular remodeling of pulmonary hypertension. Although the study of pathological changes in HPH has become clearer, the cellular mechanisms related to excessive and uncontrolled growth of vascular wall cells remain unclear. An increase in the concentration of cytosolic calcium ([Ca 2+ ] cyt ) in PASMCs is the main cause for pulmonary vasoconstriction and a critical stimulation for PASMCs proliferation and migration.[ 21 ] As the major regulator of intracellular calcium concentrations, the CaSR can respond to the changes in

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Mihaela Aldea, Lucian Craciun and Carmen Crivii

antitumor activity involve caspase-mediated endothelial cell apoptosis. Proc Natl Acad Sci U S A 101: 2476-2481, 2004. 57. Taliaferro-Smith L, Nagalingam A, Zhong D, Zhou W, Saxena NK, Sharma D. Lkb1 is required for adiponectin-mediated modulation of ampk-s6k axis and inhibition of migration and invasion of breast cancer cells. Oncogene 28: 2621-2633, 2009. 58. Tsilchorozidou T, Mohamed-Ali V, Conway GS. Determinants of interleukin-6 and c-reactive protein vary in polycystic ovary syndrome, as do effects of shortand long-term metformin