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Sakunee Khankham, Leena Chularojanamontri, Chanisada Wongpraparut, Narumol Silpa-archa, Nuttaporn Janyong and Prin Vathesatogkit

Coronary artery disease (CAD) has become an important cause of death and comorbid disease among the general population. Several assessment tools have been developed to predict the 10-year risk of developing CAD and coronary death. The Framingham Risk Score (FRS), which was developed in 1998, is probably the most well-known [ 1 ]. The FRS is validated in the U.S. population and performs well when applied to other populations with a similarly high background risk of CAD. However, application of the FRS overestimated the risk of CAD in cohorts in Europe, Asia, and

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Daria Pašalić and Natalija Marinković

References 1. Dandona S, Roberts R. The role of genetic risk factors in coronary artery disease. Curr Cardiol Rep 2014;16:479. doi: 10.1007/s11886-014-0479-2 2. Sayols-Baixeras S, Lluís-Ganella C, Lucas G, Elosua R. Pathogenesis of coronary artery disease: focus on genetic risk factors and identification of genetic variants. Appl Clin Genet 2014;7:15-32. doi: 10.2147/TACG.S35301 3. Marinković N, Pašalić D, Potočki S. Polymorphisms of genes i n v o l v e d i n p o l y c y c l i c a r o m a t i c hydrocarbons

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T Tupitsina, P Slominsky, Y Yufereva, N Perova, D Aronov and S Limborska

References Buraczynska M, Pijanowski Z, Spasiewicz D, Nowicka T, Sodolski T, Widomska - Czekajska T, Ksiazek A. Renin-angiotensin system gene polymorphisms: assessment of the risk of coronary heart disease. Kardiol Pol 2003; 58(1): 1-9. Sekuri C, Cam FS, Ercan E, Tengiz I, Sagcan A, Eser E, Berdeli A, Akin M. Renin-angiotensin system gene polymorphisms and premature coronary heart disease. J Renin Angiotensin Aldosterone Syst 2005; 6(1): 38-42. Gardemann A, Lohre J, Cayci S

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The sex-specific estimation of 10-year cardiovascular risk in individuals without cardiovascular diseases (CVD) has commonly used the Framingham Risk Score (FRS), which was developed from a large, population-based prospective cohort in the US representing mainly the white population of European ancestry [ 1 , 2 ]. Other multivariate risk models, including a risk calculator released by the Joint British Societies (JBS) in 2014 [ 3 ], and later versions of Framingham risk model have been developed to predict coronary heart disease (CHD), cerebrovascular disease

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Sombat Treeprasertsuk, Abel Romero-Corral, Virend K. Somers, Justo Sierra-Johnson, Keith D. Lindor, Paul Angulo and Francisco Lopez-Jimenez

References 1. Angulo P, Hui JM, Marchesini G, Bugianesi E, George J, Farrell GC, et al. The NAFLD fibrosis score: a noninvasive system that identifies liver fibrosis in patients with NAFLD. Hepatology. 2007; 45:846-54. 2. Church TS, Kuk JL, Ross R, Priest EL, Biltoft E, Blair SN. Association of cardiorespiratory fitness, body mass index, and waist circumference to nonalcoholic fatty liver disease. Gastroenterology. 2006; 130: 2023-30. 3. Park SH, Kim BI, Kim SH, Kim HJ, Park DI, Cho YK, et al. Body fat

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Muhammed Sait Toprak, Zeynep Gungor Ozturk, Ozlem Balci Ekmekci, Hakan Ekmekci, Baris Ikitimur, Bilgehan Karadag, Huseyin Altug Cakmak, Baris Ilerigelen and Huseyin Sonmez

intercellular adhesion molecule 1 are related in healthy subjects, and pointed out the risk of coronary heart disease [ 34 ]. Yeboah et al. showed that brachial FMD is a predictor of incident CV events in population-based adults, and that it improved the classification of individuals as low, intermediate, and high CVD risk compared with the Framingham Risk Score [ 35 ]. The contributions of biochemical endothelial markers to endothelium derived dilatation are difficult to define because their importance may vary lots of confounders. Determining endothelial function by

Open access

Zofia Radikova, Adela Penesova, Miroslav Vlcek, Andrea Havranova, Monika Sivakova, Pavel Siarnik, Ingrid Zitnanova, Richard Imrich, Branislav Kollar and Peter Turcani

Framingham risk score of coronary heart disease in middle-aged men with increased non-HDL cholesterol. Int J Cardiol 168, 3853–3858, 2013. Jorissen W, Wouters E, Bogie JF, Vanmierlo T, Noben JP, Sviridov D, Hellings N, Somers V, Valcke R, Vanwijmeersch B, Stinissen P, Mulder MT, Remaley AT, Hendriks JJ. Relapsing-remitting multiple sclerosis patients display an altered lipoprotein profile with dysfunctional HDL. Sci Rep 7, 43410, 2017. Jorissen W, Vanmierlo T, Wens I, Somers V, Van Wijmeersch B, Bogie JF, Remaley AT, Eijnde BO, Hendriks JJA. Twelve Weeks of