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Nikola Besic, Marta Dremelj, Andreja Schwartzbartl-Pevec and Barbara Gazic

. Poorly differentiated thyroid carcinoma: the Turin proposal for the use of uniform diagnostic criteria and an algorithmic diagnostic approach. Am J Surg Pathol 2007; 31: 1256-64. 4. Patel KN, Shaha AR. Poorly differentiated and anaplastic thyroid cancer. Cancer Control 2006; 13: 119-28. 5. Asioli S, Erickson LA, Righi A, Jin L, Volante M, Jenkins S. Poorly differentiated carcinoma of the thyroid: validation of the Turin proposal and analysis of IMP3 expression. Mod Pathol 2010; 23: 1269-78. 6. Ito Y, Hirokawa M, Fukushima M, Inoue H

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Hans-Jonas Meyer, Maximilian Beimler, Gudrun Borte, Wolfram Pönisch and Alexey Surov

early and accurate diagnosis is crucial. 7 However, particularly inapparent bulks pose a diagnostic challenge lacking indicatory laboratory findings. Moreover, MS can possibly involve any organ system. 4 , 5 , 8 There are only a few systematic evaluations of radiologic findings with small patient populations, mainly limited to case reports. 9 , 13 Therefore, the purpose of this study was to evaluate imaging characteristics of MS in a large patient sample and to establish possible correlations between imaging and clinical data, assess growth patterns and typically

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Martina Rebersek, Marko Boc, Petra Cerkovnik, Jernej Benedik, Zvezdana Hlebanja, Neva Volk, Srdjan Novakovic and Janja Ocvirk

treatment. Int J Oncol 2010, 36 : 1137-44. De Roock W, Jonker DJ, Di Nicolantonio F, Sartore-Bianchi A, Tu D, Siena S, et al. Association of KRAS p.G13D mutation with outcome in patients with outcome with chemotherapy- refractory metastatic colorectal cancer treated with cetuximab. JAMA 2010; 304 : 1812-20. Amado RG, Wolf M, Peeters M, Van Cutsem E, Siena S, Freeman DJ, et al. Wild- type KRAS is required for panitumumab efficacy in patients with metastatic colorectal cancer. J Clin Oncol 2008; 26 : 1626

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Andrej Zist, Eitan Amir, Alberto F. Ocana and Bostjan Seruga

. Clin Oncol (R Coll Radiol) 2011; 23: 706-8. 11. Lund L, Borre M, Jacobsen J, Sorenson HT, Norgaard M. Impact of comorbidity on survival of Danish prostate cancer patients, 1995-2006: a population-based cohort study. Urology 2008; 72: 1258-62. 12. Albertsen PC, Moore DF, Shih W, Lin Y, Lu-Yao GL. Impact of comorbidity on survival among men with localized prostate cancer. J Clin Oncol 2011; 29: 1335-41. 13. Daskivich TJ, Chamie K, Kwan L, Labo J, Dash A, Greenfield S, et al. Comorbidity and competing risks for mortality in men with prostate

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Mirta Kozelj, Samo Zver and Vesna Zadnik

. Cyclophosphamide cardiotoxicity in bone marrow transplantation: a prospective evaluation of new dosing regimens. J Clin Oncol 1991 ; 9: 15-33. 7. McDonagh TA, Robb SD, Murdoch DR Morton JJ, Ford I, Morrison CE, et al. Biochemical detection of left-ventricular systolic dysfunction. Lancet 1998; 351: 9 - 13. 8. Tsuruda T, Boerrigter G, Huntley BK, Noser JA, Cataliotti A, Costello- Boerrigter LC, et al. BNP is produced in cardiac fibroblasts and induces matrix metalloproteinases. Circ Res 2002; 91: 1127-34. 9. Maisel AS

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Wei Lu, Won Park, Barry Uchida, Hans Timmermans, Dusan Pavcnik, Frederick Keller and Josef Rösch

, Keller FS, Rösch J. Percutaneous management of chronic deep venous reflux: review of experimental work and early clinical experience with bioprosthetic valve. J Vasc Med 2008; 13: 75-84. Gomez-Jorge J, Venbrux AC, Magee C. Percutaneous deployment of a valved bovine jugular vein in the swine venous system: a potential treatment for venous insufficiency. J Vasc Interv Radiol 2000; 11: 931-6. Dalsing MC, Sawchuk AP, Lalka SG, Crikrit DF. An early experience with endovascular venous valve transplantation. J Vasc Surg

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Qingxin Meng, Weiwei Ding, Bin Yang, Ninghua Fu and Guangming Lu

, Orgaz A, Cuena R, Criado E, et al. Screening algorithm for aortoiliac occlusive disease using duplex ultrasonography-acquired velocity spectra from the distal external iliac artery. Vascular 2005; 13 : 164-72. Steinman DA, Poepping TL, Tambasco M, Rankin RN, Holdsworth DW. Flow patterns at the stenosed carotid bifurcation: Effect of concentric versus eccentric stenosis. Ann Biomed Eng 2000; 28 : 415-23. Stergiopulos N, Spiridon M, Pythoud F, Meister JJ. On the wave transmission and reflection properties of

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Jernej Avsenik, Janja Pretnar Oblak and Katarina Surlan Popovic

define optimal cutoff value for which sensitivity and specificity was calculated. A p value < 0.05 was considered significant. Results CVST was confirmed in 13 patients (9 women, 4 men; mean age, 36.5 years; age range, 19 – 82 years). Patients presented with headache (12 patients, 93%), papiloedema (7 of 9 evaluated patients, 78%), objective neurological deficit (8 patients, 62%), vomiting (8 patients, 62%), somnolence or stupor (6 patients, 46%), confusion (5 patients, 38%), disturbance of vision (3 patients, 23%) and epileptic seizures (2 patients, 15

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Aljaz Hojski, Maja Leitgeb and Anton Crnjac

Disclosure: No potential conflicts of interest were disclosed. References 1. As toul P. Pleurodesis for recurrent malignant pleural effusions: the quest for the Holy Grail. [Editorial]. Eur J Cardiothorac Surg 2011; 40: 277-9. 2. Tan C, Sedrakyan A, Browne J, Swift S, Treasure T. The evidence on the effectiveness of management for malignant pleural effusion: a systematic review. Eur J Cardiothorac Surg 2006; 29: 829-38. 3. Debeljak A, Kecelj P, Triller N, Letonja S, Kern I, Debevec L, et al. Talc pleurodesis: comparison of talc

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Tanja Mesti, Nadia Bouchemal, Claire Banissi, Mohamed N. Triba, Carole Marbeuf-Gueye, Maja Cemazar, Laurence Le Moyec, Antoine F. Carpentier, Philippe Savarin and Janja Ocvirk

using SIMCA-P12 (Umetrics) and in-house Matlab (Mathworks) code based on the Trygg and Wold method. 15 For metabolites considered as discriminant by the multivariate analysis, concentrations of metabolites were calculated by integration of their NMR signal. Results VEGF secretion was found (13 ng/mL) in the culture medium after 24 h incubation of mIDH1-U87cells ( Figure 1A ). Bevacizumab, even in concentrations up to 1 mg/mL, and regardless of the exposure time, had no effect on mIDH1-U87 cell line viability ( Figure 1B ). FIGURE 1 mIDH1-U87 vascular