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Macedonian Journal of Medical Sciences
The Journal of ID Design 2012/DOOEL Skopje, Republic of Macedonia on behalf of the Macedonian Donor Registry (MKDR), Skopje, Republic of Macedonia
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Reply to comments on “State of the art in magnetic resonance imaging of hepatocellular carcinoma”: the role of DWI

, Satani M, Shimose S, et al. Diffusion-weighted magnetic resonance imaging predicts malignant potential in small hepatocellular carcinoma. Dig Liver Dis 2016; 48: 945-52. doi: 10.1016/j.dld.2016.05.020 10.1016/j.dld.2016.05.020 27338850 Okamura S Sumie S Tonan T Nakano M Satani M Shimose S Diffusion-weighted magnetic resonance imaging predicts malignant potential in small hepatocellular carcinoma Dig Liver Dis 2016 48 945 52 10.1016/j.dld.2016.05.020 6 Granata V, Fusco R, Filice S, Catalano O, Piccirillo M, Palaia R, et al. The

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Dusp6 inhibits epithelial-mesenchymal transition in endometrial adenocarcinoma via ERK signaling pathway

Ishikawa 3H12 cells that with the overexpression/knockdown of DUSP6. Matrigel was diluted by pre-cold serum free DMEM medium at 1: 5 before use. A total number of 3x10 4 cells were seeded into the top chamber of a 24-well Matrigel-coated micropore polycarbonate membrane filter with 8μm pores (Becton Dickinson Labware, Franklin Lakes, NJ) for invasion assays. The DMEM containing 10% FBS was added to the bottom chamber as a chemoattractant. The cells were then incubated at 37°C for 22 h. The members were washed and fixed followed by stained by crystal violet. The cells

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Local recurrence of soft tissue sarcoma: a radiomic analysis

using receiver operating characteristic (ROC) analyses to estimate the area under the curve (AUC) and by estimating thresholds for sensitivity and specificity for the radiomics features that significantly differed between patients and controls, considering the mean value, to avoid over-fitting. Ninety-five percent confidence intervals (95%CIs) were calculated. Using statistical software, p values below 0.05 were considered statistically significant. C) Correlation analysis and univariate linear regression were performed to determine the association between the

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Thrombocytopenia and Coronary Artery Disease, the Existing Dilemmas

;287:449-451. doi: 10.1136/bmj.287.6390.449. 7. O'Malley T, Langhorne P, Elton RA, Stewart C. Platelet size in stroke patients. Stroke. 1995;26:995-999. 8. Asher E, Fefer P, Shechter M, et al. Increased mean platelet volume is associated with non-responsiveness to clopidogrel. Thromb Haemost. 2014;112:137-141. doi: 10.1160/TH13-10-0845. 9. VanWijk Michiel, VanBavel Ed, Nieuwland R. Microparticles in cardiovascular diseases. Cardiovasc Res. 2003;59:277-287. doi: 10.1186/1471-2121-14-23. 10. Jy W, Horstman LL, Arce M, Ahn YS. Clinical significance of

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LncRNA PVT1 promotes proliferation and invasion through enhancing Smad3 expression by sponging miR-140-5p in cervical cancer

24 h. Wounds were created by using a sterile plastic pipette tip to scratch the cell layer. Then the cells were incubated with medium containing 10% FBS for 48 h. Images were acquired by microscope. This assay was performed at least three times. Transwell assays The transwell assays were determined using transwell chambers (Corning, NY, USA) as previously described. 22 Briefly, transfected cells were suspended in serum-free medium and seeded into the upper chamber, while medium containing 10% FBS was added in the bottom chamber. After incubation at 37°C for

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Transcription factors gene expression in chronic rhinosinusitis with and without nasal polyps

change, no. (%) 5 (35.7) 4 (40) 1 (25) 0.51 2 (25) 0.53 Squamous metaplasia, no. (%) 4 (28.6) 3 (30) 1 (25) 0.85 4 (50) 0.31 Fibrosis, no. (%) 10 (71.4) 7 (70) 3 (75) 0.85 7 (87.5) 0.39 * P refers to the comparison between CRSwNP and CRSsNP; values are expressed as numbers (percentages) or medians (Q1–Q3); P < 0.05 are boldface; CRS = chronic rhinosinusitis; HPF = high power field; N.A. = not applicable, values are not indicated because these characteristics are the basis for the patient’s classification; VAS

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Advances in the management of craniopharyngioma in children and adults

Oncol 1992 24 611 17 10.1016/0360-3016(92)90705-M 50 Winkfield KM, Linsenmeier C, Yock TI, Grant PE, Yeap BY, Butler WE, et al. Surveillance of Craniopharyngioma Cyst Growth in Children Treated With Proton Radiotherapy Int J Radiat Oncol 2009; 73: 716-21. doi: Winkfield KM Linsenmeier C Yock TI Grant PE Yeap BY Butler WE Surveillance of Craniopharyngioma Cyst Growth in Children Treated With Proton Radiotherapy Int J Radiat Oncol 2009 73 716 21

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The “question-mark” MR anatomy of the cervico-thoracic ganglia complex: can it help to avoid mistaking it for a malignant lesion on 68Ga-PSMA-11 PET/MR?

sterile and endotoxin-free lyophilisate of PSMA-11 (GMP) (ABX, Radeberg, Germany) and a vial containing 60 mg of sodium acetate was used. To the above set 2ml of Ga-68 chloride was added and mixed for 10-20s. to complete dissolution. Subsequently, the mixture was incubated for 10 min. at 95°C. The labelled tracer was purified on a column of Sep-Pak Light C18 (Waters) and filtered on a 0.22 μm pore size filter (MILLEX-GV, Merck). Radiochemical purity (≥95%) was confirmed by thin-layer chromatography, checked on iTLC-SG bands in ammonium acetate-methanol (1:1) solution

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LncRNA NEAT1 promotes endometrial cancer cell proliferation, migration and invasion by regulating the miR-144-3p/EZH2 axis

cultured in 96-well plates (1 × 10 4 per well). MTT (0.5 mg/mL, Gibco, USA) was added to the medium. Then, the plate was incubated at 37°C for 4 h and the supernatant was discarded. Next, 150 μL DMSO (Thermo Fisher, USA) was added to each well and the OD490 nm value was measured immediately using a microplate reader (3100, Thermo Fisher, USA). Colony formation assay A colony formation assay was used to determine cell proliferation. HEC-1-A and Ishikawa cells in logarithmic growth were digested by trypsin (Gibco, USA) and then resuspended in DMEM containing 10% FBS

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