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D. Bakalov, M. Boyanov and A. Tsakova

. - Endocrinologia, 17, 2012, № 3, 122-134 (article in Bulgarian). 4 . Borissova, A-M., Ts. Tankova, G. Kirilov, et al. The effect of vitamin D3 on insulin secretion and peripheral insulin sensitivity in type 2 diabetic patients. - Int. J. Clin. Pract., 57, 2003, № 4, 258-261. 5 . Calle, C., M. Begoña et M. García-Arencibia. Genomic actions of 1,25-dihydroxyvitamin D3 on insulin receptor gene expression, insulin receptor number and insulin activity in the kidney, liver and adipose tissue of streptozotocin-induced diabetic rats. - BMC Molecular

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M. Drenska and I. Getov

at: http://www.gmc-uk.org/guidance/ethical_guidance/14316.asp . Last access: 2016/10/27. 10. Guideline on good pharmacovigilance practices (GVP), Annex I – Definitions (Rev 3) Available at: http://www.ema.europa.eu/docs/en_GB/document_library/Scientific_guideline/2013/05/WC500143294.pdf . Last access: 2016/10/27. 11. Legal mandate, procedures – Federal Joint Committee. Available at: http://www.english.g-ba.de/legalmandate/ . Last access: 2016/10/27. 12. Lenk, C., G. Duttge. Ethical and legal framework and regulation for off-label use: European

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M. Gulubova, J. Ananiev, M. Ignatova and K. Halacheva

. Interleukin-17: a promoter in colorectal cancer progression. Clinical and Developmental Immunology 2013; article ID 436307: 7. 34. Li L, Boussiotis V. The role of IL-17-producing Foxp3+ CD4+ T cells in infl ammatory bowel disease and colon cancer. Clin Immunol 2013;148(2): doi: 10.1016/j.clim.2013.05.003. 35. Huber M, Heink S, Pagenstecher A, et al. IL-17A secretion by CD8+ T cells supports Th17-mediated autoimmune encephalomyelitis. J Clin Invest 2013;123(1):247-260. 36. Segura E, Touzot M, Bohineust A, Cappuccio A, Chiocchia

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Ekaterina Boteva

. Boteva E. Effects of Nutrition on Dental Caries, Salivary pH and Biochemical Patterns in Metabolic Patients. Caries Research, 27, 1993, 3, 213, Abstr .24 . 5. Boteva E, C Robinson, J Kirkham. Effect of Cd and Zn on the Biomineralization of Enamel, Dentine and Bone. Caries Research, 28, 1994, 3, 207, Abstr. 94. 6. Boteva E, A Rugg-Gunn, S Higham. Remineralization of White Spot Carious Lesions with Fluoridated Milk. Caries Research, 30, 1996, 4, 307, Abstr. 124. 7. Boteva E. Delivery of Fluoride to oral tissues via milk