Search Results

1 - 6 of 6 items :

  • "vitamin C" x
Clear All
Vitamin C dosing during continuous renal replacement therapy: The last word is not said!

To the editor Pharmacokinetic and dose-response data suggest a vitamin C (vit C) dose largely exceeding 3 g daily in critically ill patients. We recently proposed higher vit C dosing in cardiac arrest patients who require continuous renal replacement therapy (CRRT).[ 1 ] In a reaction, Spoelstra-de Man et al . rebutted that increasing the vit C dose above 2 g/day during continuous veno-venous hemofiltration (CVVH) was unnecessary when normal plasma vit C concentrations are targeted. They based their standpoint on calculating less vit C removal during CVVH

Open access
A hypothetical approach on gender differences in cancer diagnosis

syndrome without an established genetic background. It is well known that malignant neoplasms occur in some families more often than it would be expected by chance and reasons for this phenomenon have mostly remained unknown. In addition, it is possible that findings about suppressive activities of vitamin C in carcinogenesis might mainly reflect the restrictive effects of this natural compound on the activity and expression of MMPs, thereby suppressing invasion, migration and metastasis, as it is well known that vitamin C is a strong inhibitor for both MMP-2 and MMP-9

Open access
Relationship of Lichen Planus, Hepatitis Virus C and Low Level of Total Antioxidant Capacity

. 2014;2014. 7. Wagner G, Rose C, Sachse MM. Clinical variants of lichen planus. JDDG: Journal der Deutschen Dermatologischen Gesellschaft. 2013;11(4):309-19. 8. Nogueira PA, Carneiro S, Ramos-e-Silva M. Oral lichen planus: an update on its pathogenesis. International journal of dermatology. 2015;54(9):1005-10. 9. Tampa M, Nicolae I, Ene CD, Sirbu I, Matei C, Georgescu SR. Vitamin C and TBARS in psoriasis vulgaris related to PASI, Rev. Chim. Buc. 2017;68(1):43-47. 10. Battino M, Greabu M, Totan A, et al. Oxidative stress markers in oral lichen

Open access
Biological therapies in psoriasis - revisited

, Berlin, Heidelberg, 2016. 5. TAMPA M, NICOLAE IL, ENE CD, et al . Vitamin C and Thiobarbituric Acid Reactive Substances (TBARS) in Psoriasis Vulgaris Related to Psoriasis Area Severity Index (PASI). REVISTA DE CHIMIE. 2017; 68 (1):43-7. 6. ŁAKUTA P, MARCINKIEWICZ K, BERGLER-CZOP B, et al . How does stigma affect people with psoriasis? Advances in Dermatology and Allergology/Postẹpy Dermatologii i Alergologii. 2017; 34 (1):36. 7. OWCZAREK K, JAWORSKI M. Quality of life and severity of skin changes in the dynamics of psoriasis . Advances in

Open access
The Green Tea Polyphenol(—)-epigallocatechin-3-gallate and its beneficial roles in chronic kidney disease

. Compared with other types of tea, green tea is unfermented and contains the highest concentration of catechins, in which EGCG accounts for as much as 50% of its total polyphenols and has been reported to possess antioxidative, antiinflammatory, and anticarcinogenic effects [6, 16] . EGCG is estimated to be 25 times more potent than vitamin E and 100 times more potent than vitamin C [ 17 ] . The kidney is essential in blood filtration, excretion of waste products, regulating the balance of electrolytes, along with maintaining homeostatic conditions, and thus at high

Open access
Renin–angiotensin–aldosterone system in insulin resistance and metabolic syndrome

Diabetes Mellitus There is a close association between hypertension and type 2 diabetes mellitus that could be attributed to the involvement of free radicals, nitric oxide (NO), eicosanoids, pro- and antiinflammatory cytokines, long-chain polyunsaturated fatty acids (PUFAs) and their metabolites, folic acid, and vitamin C in the pathogenesis of both hypertension and type 2 diabetes mellitus. For example, under physiological conditions, a balance is maintained between endothelial vasoconstrictors and vasodilators such that normal blood pressure is maintained. When this

Open access