The larger part of Pécs’s downtown area – an area that still preserves the structure of the medieval city – is protected either by local or national regulations. Although the street structure within the limits of the city wall have not changed, the cityscape has undergone more transformations, since every architectural era has left its dominant mark in the buildings. In this study I will analyse one of the most important East-West axes of the downtown, and in more specific detail the Király Street with its historically important buildings. I will describe the history of its development, its past and present function, and the changes that this area has undergone up to the present day. In addition to the architectural aspects of these changes, transport, trade, and tourism also play an important role. In this study, I would like to draw attention to the currently vacant, incorrectly used properties and opportunities for their use in the future.