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Clinical Assessment of Drug Adjunctive Therapy Effects in Association with Chronic Generalized Periodontitis and Osteoporotic Disease

J, Sorsa T. Tetracyclines inhibit connective tissue breakdown by multiple non-antimicrobial mechanisms. Adv Dent Res , 1998; 12:12-26. 4. Rifkin BR, Vernillo AT, Golub LM, Ramamurthy NS . Modulation of bone resorption by tetracyclines. Annals of the New York Academy of Sciences , 1994; 732:165-180. 5. Golub LM, Ramamurthy NS, Llavaneras A, Ryan ME, Lee HM, Liu Y, Bain S, Sorsa T . A chemically-modified nonantimicrobial tetracycline (CMT-8) inhibits gingival matrix metalloproteinases, periodontal breakdown, and extra-oral bone loss in ovariectomized

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Adjunctive Subantimicrobial Dose Doxycycline in the Treatment of Chronic Periodontitis in Type 2 Diabetic Patients: A Unique Combination Therapy

;291:223-234. 7. Ingman T, Tervahartiala T, Ding Y, Tschesche H, Haerian A, Kinane DF et al. Matrix metalloproteinases and their inhibitors in gingival crevicular fluid and saliva of periodontitis patients. J Clin Periodontol, 1996;23:1127-1132. 8. Sorsa T, Ingman T, Suomalainen K, Halinen S, Saari H, Konttinen YT et al. Cellular source and tetracycline inhibition of gingival crevicular fluid collagenase of patients with labile diabetes mellitus. J Clin Periodontol, 1992;19:146-149. 9. Correa FO, Gonçalves D, Figueredo CM, Gustafsson A, Orrico SR

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How to Maintain Oral Health in Children with Respiratory Diseases –Literature Review

Dent Res, 1976;55:991-996. 36. Primosch RE. Tetracycline discoloration, enamel defects, and dental caries in patients with cystic fibrosis. Oral Surg Oral Med Oral Pathol, 1980;50:301-308. 37. Kinirons MJ. Increased salivary buffering in association with a low caries experience in children suffering from cystic fibrosis. J Dent Res, 1983;62:815-817. 38. Kinirons MJ. Dental health of patients suffering from cystic fibrosis in Northern Ireland. Community Dent Health, 1989;6:113-120. 39. Kinirons MJ. The effect of antibiotic therapy on the oral

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The relationship between periodontal disease and diabetes mellitus


Periodontitis is a common complication in patients with diabetes. Their classification is complex and it is based on the clinical presentation, rate of disease progression, age at diagnosis and local and systemic factors that may multiply the risk. The two major stages of periodontal diseases are gingivitis and periodontitis. The relationship between these two diseases appears bidirectional insofar that the existence of one disease tends to promote the other and that the meticulous management of either may help the treatment of the other. Treatment of periodontitis using a association of mechanical therapy, scaling and root planning, plus systemic tetracycline antibiotics has been demonstrated to have important reductions in HbA1c values. Therefore, for a better control of diabetes we suggest that periodontal patients with diabetes should be consulted and treated by a periodontist.

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Successful Continuation of Peritoneal Dialysis after "Sweet" Hydrothorax

: 1702. 23. Benz RL, Schleifer CR. Hydrothorax in continuous ambulatory peritoneal dialysis: successful treatment with intrapleural tetracycline and a review of the literature. Am J Kidney Dis 1985; 5: 13640. 24. Catizone L, Zuchelli A, Zucchelli P. Hydrothorax in a PD patient: successful treatment with intrapleural autologous blood instillation. Adv Perit Dial 1991; 7: 8690. 25. Chao SH, Tsai TJ. Recurrent hydrothorax following repeated pleurodesis using autologous blood. Perit Dial Int 1993; 13: 3212. 26

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