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Study of genetic variability of Ribes L. representatives grown in Belarus

, Guiard J, Zhang D. Assessing temporal changes in genetic diversity of maize varieties using microsatellite markers, Theoretical and Applied Genetics., 2005, 110(2): 294-302. 15. Xie H, Sui Y, Chang FQ, Xu Y, Ma RC. SSR allelic variation in almond (Prunus dulcis Mill.), Theoretical and Applied Genetics., 2006, 112(2): 366-372.

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Genetic testing for atrial septal defect

8 7 Botto LD, Correa A, Erickson JD. Racial and temporal variations in the prevalence of heart defects. Pediatrics 2001; 107(3): E32. Botto LD Correa A Erickson JD Racial and temporal variations in the prevalence of heart defects Pediatrics 2001 107 3 E32 8 Chen B, Gagnon M, Shahangian S, Anderson NL, Howerton DA, Boone JD; Centers for Disease Control and Prevention (CDC). Good Laboratory Practices for Molecular Genetic Testing for Heritable Diseases and Conditions. MMWR Recomm Rep. 2009; 58(RR-6): 1-37; quiz CE-1-4. Chen B Gagnon

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Fluorescence lifetime imaging of red yeast Cystofilobasidium capitatum during growth

used as imaging technique when studying S. cerevisiae as a model organism. Lipids are accumulated in all eukaryotic cells as lipid bodies (LB), which are not a simple warehouse, but rather one of the principal compartments with function including protein degradation, temporal protein storage and also signaling ( 8 , 9 , 10 ). One reason for study such a complex system with LSCM was proposed as statement ( 11 ), that morphological alteration of LB is affected by processes maintaining neutral lipid and phospholipid homeostasis. Some of the red yeasts were found

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Low-frequency ultrasound can drive the transport of nanoparticles and molecules in polymer gels for biotechnology applications

gently inserted to retract the eyelids of the rabbit. Where necessary due to a narrow palpebral aperture, the globe was exposed by incisions at the lateral and medial canthi, removing the nictitating membrane and reflecting the eyelids. The “tracer-gel” attached to the ultrasound transducer was placed in contact with the limbal region on the temporal side of the eye. The transducer was activated to deliver the 40 kHz ultrasound for a period of 1-2 minutes. For each eye of 3 rabbits a different therapeutic molecule was tested, either incorporated directly into the

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Nanobiotechnology medical applications: Overcoming challenges through innovation

to ensure complete removal 69-71 10 NIR Fluorescence-Enhanced Diffuse Optical Tomography – multimodal use of real-time computed tomography & MRI - Tumor targeted NCs incorporating fluorescent NPs - Real-time temporal and spatial 3D imaging for the identification of biological & genetic causalities of disease - Earlier detection & removal of tumors 72-73 Theranostics for Tumor Ablation in Cancer Patients Stimuli-responsive nanoparticles are being incorporated into nanoformulations that are targeted for tumor cells, and upon radiation

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MAGI Balkans, a laboratory for the diagnosis of rare genetic diseases


Molecular diagnosis relieves patients of uncertainty, aids informed decisions about health and reproductive choices, and helps them join clinical trials or access available therapy. Genetic testing by next generation sequencing (NGS) is the suggested choice for a wide variety of disorders with heterogeneous phenotypes, alleles and loci. The development of a NGS service at MAGI Balkans, through the support of a partner, increases the availability of forefront genetic testing in Albania with great advantages for patients and their families. Here we report the NGS tests performed in collaboration with MAGI Euregio, Italy, for the diagnosis of rare genetic disease in seven probands and their families. The diseases/manifestations included ichthyosis, familial adenomatous polyposis, diabetes, syndromic craniosynostosis, fronto-temporal dementia, fragile X syndrome and ataxia. We obtained an overall detection rate of 57%. For 4/7 probands we identified a pathogenic or likely pathogenic variant, while for the others, the results did not completely explain the phenotype. All variants were confirmed by Sanger sequencing. Segregation of the variant with the affected phenotype was also evaluated.

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The music in the brain hemispheres

References 1. Bever TG, Chiarello RJ. Cerebral dominance in musicians and non-musicians. Science. 1974; 185:537-539. 2. Li E, Weng X, Han Y, Wu S, Zhuang J, Chen C, Feng L, Zhang K. Asymmetry of brain functional activation: fMRI study under language and music stimulation. Chin Med J 2000; 113:154-158. 3. Sammler D, Koelsch S, Friederici AD. Are left fronto-temporal brain areas a prerequisite for normal music-syntactic processing? Cortex 2011; 47:659-673. 4. Osborne K, Gale A Bilateral EEG

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Anatomical characterization of ADHD using an atlas-based analysis: A diffusion tensor imaging study

, Doganay S, Per H, Gorkem SB, Canpolat M, Bayram AK, Coskun A. Brain diffusion tensor imaging in children with tuberous sclerosis. Diagn Interv Imaging 2016; 97(2): 171-6. 21. Miller MI, Beg MF, Ceritoglu C, Stark C. Increasing the power of functional maps of the medial temporal lobe by using large deformation diffeomorphic metric mapping. Proc Natl Acad Sci U S A, 2005; 102(27): 9685-90. 22. Oishi K, Faria A, Jiang H, Li X, Akhter K, Zhang J, Hsu JT, Miller MI, van Zijl PC, Albert M, Lyketsos CG, Woods R, Toga AW, Pike GB, Rosa-Neto P

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Antibiotic resistance in lactococci and enterococci: phenotypic and molecular-genetic aspects

-78. 29. Salama MS, Musafija-Jeknic T, Sandine WE, Giovannoni SJ. An Ecological Study of Lactic Acid Bacteria: Isolation of New Strains of Lactococcus Including Lactococcus lactis subspecies cremoris. J Dairy Sci 1995; 78(5): 1004-17. 30. Vanhoutte T, Huys G, Brandt E, Swings J. Temporal stability analysis of the microbiota in human feces by denaturing gradient gel electrophoresis using universal and group-specific 16S rRNA gene primers. FEMS Microbiol Ecol 2004; 48(3): 437-46. 31. Lavilla Lerma L, Benomar N, Valenzuela AS, Casado Munoz M

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