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The need to improve screening and diagnostic methods in occupational irritant dermatitis


Modern medicine has increasingly directed its interest towards discovering the etiology of occupational dermatitis, but unfortunately it is not completely elucidated. As with other occupational diseases, the presence of the exposure and the temporal relation between the exposure and the appearance of the characteristic signs is a defining element, but obtaining the information on the etiological factors is not always easy, therefore the attention must be directed to a systematic collection of these data. Clinical diagnosis is not sufficient, so additional paraclinical tests are needed for a complete diagnosis. Currently, more and more emphasis is being placed on experimental studies targeting the discovery of molecular or genetic markers that complement the idea of individual susceptibility in the appearance of contact dermatitis. As frequent as it is difficult to diagnose, occupational dermatitis is still a public health problem.

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Monotherapy of experimental metabolic syndrome: II. Study of cardiovascular effects

–354. Galajda P, Mokáň M, Prídavková D, Tomásková V, Sutarík L, Krucinská L, Bukovská A, Rusnáková G. (2007). Prevalencia metabolického syndrómu na Slovensku. (Prevalence of metabolic syndrome in Slovakia. In Slovak). Int med 7 : 325–331. Gray RA, Pertsov AM, Jalife J. (1998). Spatial and temporal organization during cardiac fibrillation. Nature 392 : 75–78. Grundy SM. (2007). Controversy in Clinical Endocrinology. Metabolic Syndrome: A Multiplex Cardiovascular Risk Factor. J Clin Endocr Met 92 : 399–404. Horwich TB, MacLellan WR. (2007

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Chronic alcoholism-mediated metabolic disorders in albino rat testes

). Epigenetic changes in the rat livers induced by pyrazinamide treatment. Toxicol Appl Pharmacol 225: 293-299. Ksheerasagar RL, Kaliwal BB. (2013). Temporal eff ects of carbosulfan on testicular biochemical parameters and enzyme activities in albino mice. Int J Pharm Bio Sci 4(B): 173-181. Kuchmerovska T, Shymanskyy I, Bondarenko L, Klimenko A. (2008). Eff ects of nicotinamide supplementation on liver and serum contents of amino acids in diabetic rats. Eur J Med Res 13: 275-280. Lehmann JM, McKee DD, Watson MA, Willson TM

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Lead toxicity: a review

exposure relates to temporal changes in IQ, violent crime, and unwed pregnancy. Environ Res 83 : 1–22. Park SK, O’Neill MS, Vokonas PS, Sparrow D, Wright RO, Coull B, Nie H, Hu H, Schwartz J. (2008). Air Pollution and Heart Rate Variability: Effect Modification by Chronic Lead Exposure. Epidemiology 19 : 111–120. Patrick L. (2006). Lead toxicity, a review of the literature. Part 1: Exposure, evaluation, and treatment. Altern Med Rev 11 : 2–22. Pearce JMS. (2007). Burton’s line in lead poisoning. Eur Neurol. 57 : 118–119. Pearson HA

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Toxicity, mechanism and health effects of some heavy metals

, Hou J. (2010). Eff ect of anaerobic fermentation residues on a chromium-contaminated soil-vegetable system. Procedia Environmental Sciences 2: 1585-1597. Ferner DJ. (2001). Toxicity, heavy metals. eMed J 2(5): 1. Ferrara R, Mazzolai B, Lanzillotta E, Nucaro EA, Pirrone N. (2000). Temporal trends in gaseous mercury evasion from the Mediterranean seawaters. Sci Tot Environ 259(1-3): 183-190. Fine JS. (2000). Iron poisoning. Curr Probl Pediatr 30(3): 71-90. Flora SJS, Mittal M, Mehta A. (2008). Heavy metal

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Different experimental approaches in modelling cataractogenesis

  11 : 56-65. Kyselova Z, Garcia SJ, Gajdosikova A, Gajdosik A and Stefek M. (2005a) Temporal relationship between lens protein oxidation and cataract development in streptozotocin-induced diabetic rats. Physiol Res   54 : 49-56. Kyselova Z, Krizanova L, Soltes L and Stefek M. (2005c) Electrophoretic analysis of oxidatively modified eye lens proteins in vitro : implications for diabetic cataract. J Chromatogr A   1084 : 95-100. Lampi KJ, Shih M, Ueda Y, Shearer TR and David LL. (2002

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Collagenases and gelatinases in bone healing. The focus on mandibular fractures

., Koike T., Kitajima S. et al.: Temporal and quantitative analysis of expression of metalloproteinases (MMPs) and their endogenous inhibitors in atherosclerotic lesions. Histol Histopathol., 23, 1503, 2008.

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