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Lethal Subarachnoid and Intracerebral Haemorrhage Associated with Temporal Arteritis. A Case Report


Giant cell arteritis is a systemic inflammatory vasculitis, typically involving the superficial temporal arteries, but with possible ischemic and hemorrhagic cerebrovascular complications.

The case is reported of a patient with a clinical picture of giant cell arteritis, who had multiple occupational exposures to various infectious agents.

His initial favourable progress was followed by an atypical outcome. Despite immunosuppressive treatment, he developed fatal subarachnoid and intracerebral haemorrhages, possibly due to rupture of a microaneurysm of the posterior cerebral artery.

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A Long-Forgotten Tale: The Management of Cardiogenic Shock in Acute Myocardial Infarction

during primary percutaneous coronary intervention. Circulation. 2008;118:1810-1816. doi: 10.1161/CIRCULATIONAHA.108.780734. 18. Wayangankar SA, Bangalore S, McCoy LA, et al. Temporal trends and outcomes of patients undergoing percutaneous coronary interventions for cardiogenic shock in the setting of acute myocardial infarction: a report from the CathPCI Registry. J Am Coll Cardiol Intv. 2016;9:341-351. doi: 10.1016/j.jcin.2015.10.039. 19. Taylor R. White coat tales: Medicine’s heroes, heritage and misadventures. New York: Springer

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Particularities of Acute Myocardial Infarction in Young Adults

among young adults with acute myocardial infarction: Results from the VIRGO study. Am Heart J. 2017;183:74-84. doi: 10.1016/j.ahj.2016.09.012. 25. Kehera S, Kolte D, Gupta T, et al. Temporal trends and sex differences in revascularization and outcomes of ST-segment elevation myocardial infarction in young adults in the United States. J Am Coll Cardiol. 2015;66:1961-1972. doi: 10.1016/j.jacc.2015.08.865. 26. Incalcaterra E, Caruso M, Lo Presti R, Caimi G. Myocardial infarction in young adults: risk factors, clinical characteristics and prognostic according

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Original research. The Assessment of Epicardial Adipose Tissue in Acute Coronary Syndrome Patients. A Systematic Review

;2:114-121. doi: 10.1515/jce-2016-0018. 68. Husser O, Bodi V, Sanchis J, et al. White blood cell subtypes after STEMI: temporal evolution, association with cardiovascular magnetic resonance-derived infarct size and impact on the outcome. Inflammation. 2011;34:73-84. doi: 10.1007/s10753-010-9209-0. 69. Odeberg J, Freitag M, Forssell H, et al. Influence of preexisting inflammation on the outcome of acute coronary syndrome: a cross-sectional study. 2016;5:e009968. doi: 10.1136/bmjopen-2015-009968. 70. Tanindi A, Erkan A, Ekici B

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Endotracheal Tube Biofilm and its Impact on the Pathogenesis of Ventilator-Associated Pneumonia


Ventilator-associated pneumonia (VAP) is a common and serious nosocomial infection in mechanically ventilated patients and results in high mortality, prolonged intensive care unit- (ICU) and hospital-length of stay and increased costs. In order to reduce its incidence, it is imperative to better understand the involved mechanisms and to identify the source of infection. The role of the endotracheal tube (ET) in VAP pathogenesis became more prominent over the last decades, along with extensive research dedicated to medical device-related infections and biofilms. ET biofilm formation is an early and constant process in intubated patients. New data regarding its temporal dynamics, composition, germ identification and consequences enhance knowledge about VAP occurrence, microbiology, treatment response and recurrence. This paper presents a structured analysis of the medical literature to date, in order to outline the role of ET biofilm in VAP pathogenesis and to review recommended methods to identify ET biofilm microorganisms and to prevent or decrease VAP incidence.

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The Efficacy of Questionnaire-based Evaluation in Determining the Incidence of Recent Pseudophakic Dysphotopsia


Background: Dysphotopsias are optical side effects experienced by patients who underwent cataract surgery. This unwanted photic phenomenon has gained ground and is a major postoperative concern. Visual acuity is not sufficient in evaluating the postoperative visual function.

The aim of this study was to determine the efficacy of using a preexistent questionnaire in determining the presence of dysphotopsia.

Material and method: We conducted a prospective study, using the modified Visual Function Index (VF-14) and the Ocular Surface Disease Index (OSDI) surveys, completed on patients that underwent uncomplicated phacoemulsification with intraocular lens implantation between November 2016 and November 2017. Patients included in the study had no known ocular comorbidities and had no other possible postoperative explanation for these visual phenomena. Three weeks after the surgery, the questionnaire was filled up by one individual examiner.

Results: Of the 50 patients considered, 37 patients met all the inclusion criteria and were successfully enrolled in the study, with a mean age of 75.88 years. Dysphotopsia phenomena were present in 13.51% of cases; 60% of these patients described the presence of positive dysphotopsia, and 40% complained of temporal shadows. The best corrected visual acuity was over 0.8 in 75.67% of the cases.

Conclusion: Although there is no objective test to diagnose this early postoperative complication, pseudophakic dysphotopsia should not be overlooked and additional chair time is needed.

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Sudden Cardiac Death and Post Cardiac Arrest Syndrome. An Overview

Maastricht area on incidence, characteristics and survival. J Am Coll Cardiol. 1997;15;30(6):1500-1505. 4. Lloyd-Jones D, Adams R, Carnethon M, et al. Heart Disease and stroke statistics - 2009 update. A report from the American Heart association Statistics Committee and Stroke Statistics Subcommittee. Circulation. 2009;119:480-6. 5. Rea TD, Eisenberg MS, Becker LJ, Murray JA, Hearne T. Temporal trends in sudden cardiac arrest: a 25-year emergency medical services perspective. Circulation. 2003;107:2780-2785. 6. Rea TD

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Association between the Incidence of Sudden Cardiac Arrest and the Location of Culprit Lesions in STEMI Patients – Design of a Prospective Clinical Study

, Agewall S, et al. 2017 ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation. Eur Heart J . 2018;39:119-177. 5. Khera S, Kolte D, Gupta T, et al. Temporal Trends and Sex Differences in Revascularization and Outcomes of ST-Segment Elevation Myocardial Infarction in Younger Adults in the United States. J Am Coll Cardiol . 2015;66:1961-1972. 6. Atwood C, Eisenberg MS, Herlitz J, Rea TD. Incidence of EMS-treated out-of-hospital cardiac arrest in Europe. Resuscitation . 2005;67:75-80. 7. Dumas F

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In-stent Flow Hemodynamics and the Risk of STent Failure Following Bioresorbable Vascular ScAFFolds Implantation – the STAFF Study

REFERENCES 1. Cardiovascular diseases. Available at: 2. Windecker S, Kolh P, Alfonso F, et al. 2014 ESC/EACTS Guidelines on myocardial revascularization. The Task Force on Myocardial Revascularization of the European Society of Cardiology (ESC) and the European Association for Cardio-Thoracic Surgery (EACTS). Eur Heart J . 2014;35:2541-2619. 3. Montone RA, Niccoli G, De Marco F et al. Temporal Trends in Adverse Events After Everolimus-Eluting Bioresorbable Vascular Scaffold Versus Everolimus

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The Role of Angiopoietine-2 in the Diagnosis and Prognosis of Sepsis

. Mearelli F, Fiotti N, Altamura N, et al. Heterogeneous models for an early discrimination between sepsis and non-infective SIRS in medical ward patients: a pilot study. Intern Emerg Med. 2014;9:749-57. 14. Giuliano JS Jr, Tran K, Li FY, Shabanova V, Tala JA, Bhandari V. The temporal kinetics of circulating angiopoietin levels in children with sepsis. Pediatr Crit Care Med. 2014;15:e1-8. 15. Gores KM, Delsing AS, Kraus SJ, et al. Plasma Angiopoietin-2 concentrations are related to impaired lung function and organ failure in a clinical cohort receiving high

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