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Lethal Subarachnoid and Intracerebral Haemorrhage Associated with Temporal Arteritis. A Case Report


Giant cell arteritis is a systemic inflammatory vasculitis, typically involving the superficial temporal arteries, but with possible ischemic and hemorrhagic cerebrovascular complications.

The case is reported of a patient with a clinical picture of giant cell arteritis, who had multiple occupational exposures to various infectious agents.

His initial favourable progress was followed by an atypical outcome. Despite immunosuppressive treatment, he developed fatal subarachnoid and intracerebral haemorrhages, possibly due to rupture of a microaneurysm of the posterior cerebral artery.

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Endotracheal Tube Biofilm and its Impact on the Pathogenesis of Ventilator-Associated Pneumonia


Ventilator-associated pneumonia (VAP) is a common and serious nosocomial infection in mechanically ventilated patients and results in high mortality, prolonged intensive care unit- (ICU) and hospital-length of stay and increased costs. In order to reduce its incidence, it is imperative to better understand the involved mechanisms and to identify the source of infection. The role of the endotracheal tube (ET) in VAP pathogenesis became more prominent over the last decades, along with extensive research dedicated to medical device-related infections and biofilms. ET biofilm formation is an early and constant process in intubated patients. New data regarding its temporal dynamics, composition, germ identification and consequences enhance knowledge about VAP occurrence, microbiology, treatment response and recurrence. This paper presents a structured analysis of the medical literature to date, in order to outline the role of ET biofilm in VAP pathogenesis and to review recommended methods to identify ET biofilm microorganisms and to prevent or decrease VAP incidence.

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Sudden Cardiac Death and Post Cardiac Arrest Syndrome. An Overview

Maastricht area on incidence, characteristics and survival. J Am Coll Cardiol. 1997;15;30(6):1500-1505. 4. Lloyd-Jones D, Adams R, Carnethon M, et al. Heart Disease and stroke statistics - 2009 update. A report from the American Heart association Statistics Committee and Stroke Statistics Subcommittee. Circulation. 2009;119:480-6. 5. Rea TD, Eisenberg MS, Becker LJ, Murray JA, Hearne T. Temporal trends in sudden cardiac arrest: a 25-year emergency medical services perspective. Circulation. 2003;107:2780-2785. 6. Rea TD

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The Role of Angiopoietine-2 in the Diagnosis and Prognosis of Sepsis

. Mearelli F, Fiotti N, Altamura N, et al. Heterogeneous models for an early discrimination between sepsis and non-infective SIRS in medical ward patients: a pilot study. Intern Emerg Med. 2014;9:749-57. 14. Giuliano JS Jr, Tran K, Li FY, Shabanova V, Tala JA, Bhandari V. The temporal kinetics of circulating angiopoietin levels in children with sepsis. Pediatr Crit Care Med. 2014;15:e1-8. 15. Gores KM, Delsing AS, Kraus SJ, et al. Plasma Angiopoietin-2 concentrations are related to impaired lung function and organ failure in a clinical cohort receiving high

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Congenital Heart Disease Requiring Maintenance of Ductus Arteriosus in Critically Ill Newborns Admitted at A Tertiary Neonatal Intensive Care Unit

R eferences 1. Hoffman JI, Kaplan S. The incidence of congenital heart disease. J Am Coll Cardiol. 2002;39:1890–900. 2. Oster ME, Lee KA, Honein MA, Riehle-Colarusso T, Shin M, Correa A. Temporal trends in survival among infants with critical congenital heart defects. Pediatrics. 2013;131:e1502-8. doi: 10.1542/peds.2012-3435. 3. Reller MD, Strickland MJ, Riehle-Colarusso T, Mahle WT, Correa A. Prevalence of congenital heart defects in metropolitan Atlanta, 1998-2005. J Pediatr. 2008;153:807-13. doi: 10.1016/j.jpeds.2008.05.059 4. Yun SW

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Increased Susceptibility to Postoperative PCA Morphine-Induced Respiratory Depression in a Patient with an Undiagnosed Traumatic Porencephalic Cyst – A Case Report

patient was immediately intubated using propofol and esmeron rapid sequence induction, a pulsating structure was noticed in the left parietal head region. Blood pressure was invasively monitored and the patient received continuous propofol infusion and continuing mechanically ventilation. The patient was referred for a cranial CT scan which revealed a large porencephalic cyst located in the frontoparietal and temporal left lobes, communicating with the left lateral ventricle ( Figure 1A, B, C) . The porencephalic cyst measured 7.8 cm in the sagittal plane and 5cm in

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