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Metody cytogenetyki molekularnej w różnicowaniu agresywnych B-NHL

+*/- +*/- +*/- - Złożony HGBL z rearanżacją MYC , BCL2 i/lub BCL6 + + +/- - Złożony * Jako pojedyncza zmiana Ryc. 2 Wynik badania aCGH (CytoSure Haematological Cancer and SNP Array (8x60k), Oxford Gene Technology, Yarnton, UK) oraz FISH z zastosowaniem sond (Vysis Abbott Molecular, Downers, Grove, IL): centromerowej CEP-11-Aq widocznej w kolorze niebieskim, rozdzielczej MLL(KMT2A) w kolorze żółtym oraz telomerowej TelVysion 11q w kolorze czerwonym a. Duża duplikacja dup(11)(q13q23.3) z terminalną delecją del(11)(q23.3q25), aCGH sondy w

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Znaczenie techniki aCGH w nowotworach mieloproliferacyjnych – przegląd literatury

Clinical utility of array CGH for the detection of chromosomal imbalances associated with mental retardation and multiple congenital anomalies Ann NY Acad Sci 2009 1151 157 66 [35] Kallioniemi A. CGH microarrays and cancer. Curr Opin Biotechnol 2008;19:36–40. 18162393 10.1016/j.copbio.2007.11.004 Kallioniemi A CGH microarrays and cancer Curr Opin Biotechnol 2008 19 36 40 [36] Manning M, Hudgins L. Array-based technology and recommendations for utilization in medical genetics practice for detection of chromosomal abnormalities. Genet Med 2010

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Progressive arthropathy in the course of immune tolerance induction failure in a child with hemophilia A and FVIII inhibitor – a case report

be more effective. A new therapeutic option for all hemophilia A with inhibitor is the use of Fc fusion technology (rFVIIIFc) to prolong circulation in the body. Recombinant factor VIII Fc fusion protein demonstrated rapid time to tolerization in high-risk first-time ITI patients [ 8 ]. Treatment of these disorders has focused on replacement of the missing coagulation factor to prevent or treat bleeding. New technologies and insights into hemostasis have driven the development of many promising new therapies for hemophilia and von Willebrand disease. Emerging

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Prognostic value of soluble angiotensin II receptor 1 and soluble angiotensin converting enzyme (CD 143) in patients with acute leukemia

Basic haematological techniques In: Practical haematology 13th (ed) Edingburgh, London, Melbourne, New York. Churchill Livingstone 2009 3 19 – 46 [17] Leng S, McElhaney J, Walston J, Xie D, Fedarko N, Kuchel G. Elisa and multiplex technologies for cytokine measurement in inflammation and aging research. J Gerontol A Biol Sci Med Sci 2008;63:879–84. 10.1093/gerona/63.8.879 Leng S McElhaney J Walston J Xie D Fedarko N Kuchel G Elisa and multiplex technologies for cytokine measurement in inflammation and aging research J Gerontol A Biol

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Immunoterapia z użyciem przeciwciał monoklonalnych ukierunkowanych na szlak PD-1/PD-L1 w chorobach nowotworowych
Monoclonal antibodies against PD-1/PD-L1 pathway

Technology; 2010;7(5):389–95. Zhang Y Huang S Gong D Qin Y Shen Q Programmed death-1 upregulation is correlated with dysfunction of tumor-infiltrating CD8+ T lymphocytes in human non-small cell lung cancer Cell Mol Immunol. Chinese Society of Immunology and The University of Science and Technology; 2010 7 5 389 – 95 [50] Zheng H, Liu X, Zhang J, Rice SJ, Wagman M, Kong Y, et al. Expression of PD-1 on CD4+ T cells in peripheral blood associates with poor clinical outcome in non-small cell lung cancer. Oncotarget. 2016;7(35):56233–56240. Zheng

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