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Functions of circular RNAs involved in animal skeletal muscle development – a review

. Mol. Cell., 56: 55–66. Bassel-Duby, R., and Olson, E. N. (2006). Signaling pathways in skeletal muscle remodeling. Annu. Rev. Biochem.,75: 19–37. Chen, L. L., and Yang, L. (2015). Regulation of circRNA biogenesis. RNA Biol.12, 381–388 Du, W. W., Yang, W., Liu, E., Yang, Z., Dhaliwal, P., and Yang, B. B. (2016). Foxo3 circular RNA retards cell cycle progression via forming ternary complexes with p21 and CDK2. Nucleic Acids Res., 44: 2846–2858. Ivanov, A., Memczak, S., Wyler, E., Torti, F., Porath, H. T., Orejuela, M. R., Piechotta, M., Levanon

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Mechanism and Functions of Identified miRNAs in Poultry Skeletal Muscle Development – A Review

References Accili D., Arden K.C. (2004). FoxOs at the crossroads of cellular review metabolism, differentiation, and transformation. Cell, 117: 421–426. Andreote A.P.D., Rosario M.F., Ledur M.C., Jorge E.C., Sonstegard T.S., Matukumalli L., Coutinho L.L. (2014). Identification and characterization of microRNAs expressed in chicken skeletal muscle. Genet. Mol. Res., 13: 1465–1479; https://doi.org/10.4238/2014.March.6.5 . Baquero-Perez B., Kuchipudi S.V., Nelli R.K., Chang K.C. (2012). A simplified but robust method for the isolation of avian and

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A Retrospective Radiographic Study Regarding Diffuse Idiopathic Skeletal Hyperostosis (Dish) in Dogs

References Bossens K., Bhatti S., Van Soens I., Gielen I., Van Ham L., 2016. Diffuse idiopathic skeletal hyperostosis of the spine in a nine-year-old cat. Journal of Small Animal Practice, 57 (1), 33-35. Ciepluch F.M., Da Costa C.R., Russel D., 2015. Imagind diagnosis - an atypical presentation of diffuse idiopathic skeletal hyperostosis (DISH) in a dog. Veterinary Radiology and Ultrasound, 56 (1), E5-E8. De Decker S., Volk H.A., 2014. Dorsal vertebral column abnormalities in dogs with disseminated idiopathic

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Association of the Expression Level of the MYBPC1 Gene in Skeletal Muscle With Marbling Trait in Japanese Black Beef Cattle

composition of other major muscles of the beef carcass. J. Anim. Sci., 69: 631-640. Busboom J.R.,Jeremiah L.E.,Gibson L.L., Johnson K.A., Gaskins C.T., R e e v e s J. J., Wri ght R.W. (1993). Effects of biological source on cooking and palatability attributes of beef produced for the Japanese market. Meat Sci., 35: 241-258. Chen Z., Zhao T.J., Li J., Gao Y.S., Meng F.G., Yan Y.B., Zhou H.M. (2011). Slow skeletal muscle myosin-binding protein-C (MYBPC1) mediates recruitment of muscle-type creatine kinase (CK) to myosin. Biochem. J., 436: 437

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Mitochondrial theory of skeletal muscle ageing –new facts, new doubts

mitochondria DNA copy number and cytochrome c oxidase gene expression in rat skeletal muscle, liver, and heart. J Biol Chem 2000, 275, 3343–3347. 4. Barrciro E., Cornell C., Lavina B., Ramirez-Sarmiento A., Orozco-Levi M., Gea J.: Aging sex differences and oxidative stress in human respiratory and limb muscles. Free Radic Biol Med 2006, 41, 797–809. 5. Barrientos A., Casademont J., Cardellach F.: Qualitative and quantitative changes in skeletal muscle mtDNA and expression of mitochondrial-encoded genes in the human aging process. Biochem Mol Med 1997, 62, 165

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Immunohistochemical Detection of Vasa Antigen and Apoptosis-Related DNA Fragmentation in Ovaries of Sheep Fetuses Prenatally Exposed to Vitamin D Deficiency

commercially available assays. PLoSONE 2010, 5(7): e11555. 24. Owens DJ, Webber D, Impey SG, Tang J, Donovan TF, Fraser WD, Morton JP, Close GL: Vitamin D supplementation does not improve human skeletal muscle contractile properties in insufficient young males. European Journal of Applied Physiology 2014, 114(6): 1309-1320. 25. Fouladi-Nashta AA, Alberio R, Kafi M, Nicholas B, Campbell KH, Webb R: Differential staining combined with TUNEL labelling to detect apoptosis in preimplantation bovine embryos. Reproduction Biomed Online 2005, 10(4): 497-502. 26

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Synovial fluid MMP-2 and MMP-9 levels in internal or external fixation for intra-articular fractures / Poziom MMP-2 i MMP-9 w mazi stawowej przy wewnętrznym i zewnętrznym zespoleniu po złamaniach wewnątrzstawowych

Abstract

The purpose of this study was to evaluate whether internal fixation or external skeletal fixation (ESF) results in better “joint health” following traumatic injury to the stifle by assessing lameness and measuring matrix metalloproteinase MMP-2 and MMP-9. Dogs with skin grafts and transarticular ESFs were included in group A. Dogs with intra-articular fractures of the distal femur were randomly divided into groups B and C, and treated with either internal or ESF, respectively. Dogs in group D had diaphyseal tibial fractures treated with ESF. Synovial fluid samples were collected pre-operatively and again 7 days and 30 days postoperatively to measure MMP-2 and -9 levels via zymography. Preoperative MMP-9 levels were higher in groups B and C than A and D. Over time, MMP-2 levels increased in groups A-C, and MMP-9 levels significantly decreased in groups B and C by 30 days postoperatively. ESF appears superior to internal fixation for repair of intra-articular fractures of the distal femur, and MMP-2 and MMP-9 could serve as markers of either fracture healing or overall joint health, particularly in the setting of PTOA.

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Histological and Histochemical Properties of M. Semitendinosus in German Landrace Pigs at Birth and Market Weight/Histološke I Histohemijske Osobine M. Semitendinosus-A Svinja Rase Nemački Landras Na Rođenju I Na Završetku Tova

postnatal skeletal muscle cell growth as infl uenced by selection, Livest Prod Sci 2000, 66:177-188. 5. Rehfeldt C, Henning M, Fiedler I: Consequences of pig domestication for skeletal muscle growth and cellularity, Livest Sci 2008, 116:30-41. 6. Berard J, Kalbe C, Losel D, Tuchscherer A, Rehfeldt C: Potential sources of early-postnatal increase in myofi bre number in pig skeletal muscle, Histochem Cell Biol 2011,136:217-225. 7. Dokmanović M, Baltić Ž M, Marković R, Bošković M, Lončina J, Glamočlija N, Đorđević M

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Effect of Subclinical and Overt Form of Rat Maternal Hypothyroidism on Offspring Endochondral Bone Formation

-Garay R, Miralles-Flores C, Obregon MJ, del Rey FE, de Escobar GM, Delgado-Baeza E: Maternal hypothyroidism and fetal chondro-osseous development in rats. Neonatology 1991, 60:385−394. 10. Ahmed M, Janjua Z: Effect of hypothyroidism and thyroxin replacement on growth of long bones in prenatally treated albino rats. J Pak Med Assoc 2003, 53:18−20. 11. Bassett JD, Williams GR: Role of thyroid hormones in skeletal development and bone maintenance. Endocr Rev 2016, 37:135−187. 12. De Escobar GM, Obregón MJ, Del Rey FE: Role of

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The Role of Apoptosis and Autophagy in Bovine Abortions Associated with Brucella Spp

Abstract

This study is aimed to evaluate the relationship between the severity of apoptotic and autophagic cell death based on the distribution of Brucella spp. antigens in the lung, liver, kidney, spleen, brain, heart, skeletal muscle, mesenteric lymph node, and thymus tissue from bovine fetuses aborted due to natural infection with Brucella spp. The distribution of Brucella spp. antigens was immunohistochemically examined in the tissues of 16 aborted fetuses from cattle diagnosed with Brucella spp. infection by a polymerase chain reaction (PCR). In addition, immunostaining of primary antibodies for cleaved caspase 3 was performed to detect apoptosis, and immunostaining of Microtubule Associated Protein 1 Light Chain 3 Beta (LC3B) was used to detect autophagy in the Brucella spp.- related abortions. Analysis of cellular death revealed strong immunopositivity in the lung, spleen, kidney, and thymus, moderate immunopositivity in the liver, mesenterial lymph nodes, and heart muscle and slight immunopositivity in the brain and skeletal muscle by staining of Brucellaspp. antigens. According to the immunohistochemical results, the immunopositivity of cleaved caspase 3 and LC3B was extremely high in the lung, thymus, spleen, kidney, and liver tissues. The immunostaining of cleaved caspase 3 in the lung, thymus, and kidney tissues was severe compared to that of LC3B. In the liver, spleen, and mesenterial lymph nodes, the immunopositivity of LC3B was higher than that of cleaved caspase 3. Bacterial antigens were highly evident in the lung, spleen, kidney, and thymus tissues of Brucella spp.-related bovine abortions, and both apoptosis and autophagy played a role in cellular death.

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