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Hypokalemic periodic paralysis – the importance of patient education


Hypokalemic periodic paralysis (HOKPP) is a rare neuromuscular disorder caused by altered transport of cellular potassium that leads to significant muscle weakness of the extremities. Paralytic attacks are induced by a drop in the serum potassium level and they have been associated with specific triggers. This case describes a 21-year-old male who has had recurrent presentations of acute paralytic attacks following vigorous physical activity. At presentation, this patient exhibited flaccid paralysis of all skeletal muscles below the neck, but was alert and oriented with stable vital signs. The patient was found to have a potassium level of 2.1 mmol/L and an EKG demonstrating U waves (characteristic of hypokalemia). The patient was treated with potassium supplementation with resolution of symptoms. The mainstay of prevention of long term permanent muscle weakness is avoidance of triggers that can lead to hypokalemia. Through education on disease process and lifestyle modifications, we were able to end the cycle of recurrent hospital readmissions and the subsequent financial burden this generated for the patient and his family.

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Comparison of the Whole-Body Bone Scintigraphy with Levels of the Markers of Bone Metabolism in Serum of Patients with Malignant Melanoma

. Multiple Metastasis-Like Bone Lesions in Scintigraphic Imaging. J Biomed Biotechnol 2012; 2012: 957364. 8. Brenner AI, Koshy J, Morey J, Lin C, DiPoce J. The bone scan. Semin Nucl Med 2012; 42(1): 11-26. 9. Ghosh P. The role of SPECT/CT in skeletal malignances. Semin Musculoskelet Radiol 2014; 18(2): 175-93. 10. Krzhivitskii PI, Kanaev SV, Novikov SN, Zhukova LA, Ponomarëva OI, Negustorov IuF. SPECT-CT in the diagnosis of metastatic skeletal lesion. Vopr Onkol 2014; 60(1): 56-63. 11. Kuwert T. Bone Imaging

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Oxidative Damage to Proteins and Lipids During Ageing

-8 Long J, Wang X, Gao H, Liu Z, Liu C, Miao M, Liu J. Malonaldehyde acts as a mitochondrial toxin: Inhibitory effects on respiratory function and enzyme activities in isolated rat liver mitochondria. Life Sci. 2006; 79(15): 1466-7 Kumaran S, Subathra M, Balu M, Panneerselvam C. Age-associated decreased activities of mitochondrial electron transport chain complexes in heart and skeletal muscle: role of L-carnitine. Chem Biol Interact. 2004; 148(1-2): 11-8 Tatarková Z, Kuka S, Račay P, Lehotský J, Dobrota D, Mištuna D

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Possible impact of automotive industry on the health of working population

selected automotive industry. Pracovní lékařství 2015; 67(3-4):86-91. (in Slovak) 16. Šišová R, Záborský T, Jakušová V, Hudečková H. The public health importance of physical load assessment. In: Proceedings of the International Scientific Conference Ergonomy 2017; 2017 Nov 29-30; Ostrava, Czech Republic. Žilina: Slovak ergonomic society; 2017. p. 81-89. (in Slovak) 17. Magee DJ, Zachazewski JE, Quillen WS, Manske RC. Pathology and Intervention in Mus cu lo - skeletal Rehabilitation. Missouri: Saunders; 2016. 18. US Bureau of Labor statistics

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Non-alcoholic fatty pancreas disease – practices for clinicians

.F. Complementary measures for promoting insulin sensitivity in skeletal muscle. Med. Hypotheses 1998; 51 (6): 451-464. 88. WRÓBEL M.P., MAREK B., KAJDANIUK D., ROKICKA D., SZYMBORSKA-KAJANEK A., STROJEK K. Metformin – a new old drug . Endokrynol. Pol. 2017; 68 (4): 482-496. 89. PIRO S., RABUAZZO A.M., RENIS M., PURRELLO F. Effects of metformin on oxidative stress, adenine nucleotides balance, and glucose-induced insulin release impaired by chronic free fatty acids exposure in rat pancreatic islets. J. Endocrinol. Invest. 2012; 35 (5): 504-510. 90

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Increased breathing resistance compromises the time course of rhythmical forearm movements—a pilot study

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Lipodystrophy HIV-related and FGF21: A new marker to follow the progression of lipodystrophy?

, fasting triglycerides, body mass index, and waist-to-hip ratio [ 27 ] . In a recent paper, it has been demonstrated that FGF-21 mRNA expression is increased in skeletal muscle in patients with HIV-related lipodystrophy and that FGF-21 mRNA expression in muscle is associated with decreased limb fat mass, increased waist-to-hip ratio, and increased triglycerides [ 28 ] . Another well-conducted study found highly significant correlation between FGF21 levels and indicators of altered fat distribution in lipodystrophy and a positive relationship between FGF21 levels and

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From Symptoms and Signs to Diagnosis in a Rare Disease, Type I Gaucher Disease

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Proliferating Myositis: An Inflammatory Lesion often Misdiagnosed as A Malignant Tumor

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Sarcopenia in diabetic nephropathy: a cross-sectional study

, BROUDEAU R, KAMMERER C, et al. Health, aging, and body composition study. Accelerated loss of skeletal muscle strength in older adults with type 2 diabetes: the health, aging, and body composition study. Diabetes Care. 2007; 30 :1507-1512. 11. PARK SW, GOODPASTER BH, LEE JS, KULLER LH, BOUDREAU R, DE REKENEIRE N, et al ., Health, aging, and body composition study. Excessive loss of skeletal muscle mass in older adults with type 2 diabetes . Diabetes Care. 2009; 32 :1993-1997. 12. SAYER AA, DENNİSON EM, SYDDALL HE, GILBODY HJ, PHILLIPS DI, COOPER C

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