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Clinical Proteomics in Kidney Disease: From Discovery to Clinical Application

diseases: unraveling the pathophysiology and biomarker discovery. Expert Rev Proteomics. 2005; 2(3): 349-366. 5. Andersen S, Mischak H, Zürbig P et al. Urinary proteome analysis enables assessment of renoprotective treatment in type 2 diabetic patients with microalbuminuria. BMC Nephrol. 2010; 11(1): 29- 6. Stalmach A, Albalat A, Mullen W, and Mischak H. Recent advances in capillary electrophoresis coupled to mass spectrometry for clinical proteomic applications. Electrophoresis. 2013; 34(11): 1452-1464. 7. Pontillo C, Filip S, Borras DM et al. CE

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Proteomics in Diagnosis of Prostate Cancer/ Протеомика Во Дијагноза На Простатниот Карцином

-dimensional gel electrophoresis in proteomics: a tutorial. J Proteomics. 2011; 74(10): 1829-1841. 32. Oliveira BM, Coorssen JR, Martins-de-Souza D. 2DE: the phoenix of proteomics. J Proteomics. 2014; 104: 140-150. 33. Link AJ, Eng J, Schieltz DM, et al. Direct analysis of protein complexes using mass spectrometry. Nat Biotechnol. 1999; 17(7): 676-682. 34. Patel VJ, Thalassinos K, Slade SE, et al. A comparison of labeling and label-free mass spectrometrybased proteomics approaches. J Proteome Res. 2009; 8(7): 3752

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Lesch-Nyhan disease: A rare disorder with many unresolved aspects

encoding hypoxanthine guanine phosphoribosyltransferase Proc Natl Acad Sci USA 2012 109 9 3377 – 82 https://doi.org/10.1073/pnas.1118067109 90 Dammer EB, Göttle M, Duong DM, Hanfelt J, Seyfried NT, Jinnah HA. Consequences of impaired purine recycling on the proteome in a cellular model of Lesch–Nyhan disease. Mol Genet Metab. 2015;114(4):570–9. https://doi.org/10.1016/j.ymg-me.2015.02.007 10.1016/j.ymgme.2015.02.007 Dammer EB Göttle M Duong DM Hanfelt J Seyfried NT Jinnah HA Consequences of impaired purine recycling on the proteome in a cellular

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