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Skin Tissue Surface Morphology and Quality of RNA and Protein Extracted from Fresh and Stabilized Human Cleft Lip and Palate Tissue

allowing morphological and molecular analyses using a single tissue section. Laboratory Investigation. 2005: 85: 1416-28. 19. Ikeda K, Monden T, Kanoh T, et al. Extraction and Analysis of Diagnostically Useful Proteins from Formalin-fixed, Paraffinembedded Tissue Sections. The Journal of Histochemistry & Cytochemistry. 1998: 46(3): 397-403. 20. Guo T, Wang W, Rudnick PA, et al. Proteome Analysis of Microdissected Formalin-fixed and Paraffin-embedded Tissue Specimens. J Histochem Cytochem. 2007: 55(7): 763-72. 21. Periayah

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Urinary Protein Biomarkers in Chronic Kidney Disease

-1862. 24. Caubet C, Lacroix C, Decramer S, et al. Advances in urinary proteome analysis and biomarker discovery in pediatric renal disease. Pediatr Nephrol 2010; 25(1): 27-35. 25. Fliser D, Novak J, Thongboonkerd V, et al. Advances in urinary proteome analysis and biomarker discovery. J Am Soc Nephrol 2007; 18(4): 1057-1071. 26. Dakna M, Harris K, Kalousis A, et al. Addressing the challenge of defining valid proteomic biomarkers and classifiers. BMC Bioinformatics 2010; 11(594): 1471-2105. 27. Siwy J, Schanstra JP, Argiles

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Pathogenesis of Type 1 Diabetes Mellitus: A Brief Overview

References Karlsen AE, Sparre T, Nielsen K, Nerup J, Pociot F. Proteome analysis - a novel approach to understand the pathogenesis of type 1 diabetes mellitus. Dis Markers 17: 205-216, 2001. Redondo MJ, Rewers M, Yu L, Garg S, Pilcher CC, Elliott RB, Eisenbarth GS. Genetic determination of islet cell autoimmunity in monozygotic twin, dizygotic twin, and non-twin siblings of patients with type 1 diabetes: prospective twin study. BMJ 318: 698-702, 1999. Karavanaki K, Tsoka E

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Aplastic anemia in China

cytotoxic T lymphocytes and thus ultimately led to the apoptosis of hematopoietic cells. Although understanding of the immune pathogenesis of SAA gradually improved after many years of research, which antigen activated mDCs and even T cells was still unclear. Actually, the immune-initiating antigen has become the focus of our further research. Newly, we have investigated the proteome of mDCs to further explore the possible antigen that leads to immune activation in SAA. Our research have demonstrated that there are changes in protein expression levels in the SAA group

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Urine biomarkers in renal allograft

identifies biomarkers for acute rejection J Am Soc Nephrol 2010 21 646 53 38 Singh S, Wu T, Xie C, Vanarsa K, Han J, Mahajan T, et al . Urine VCAM-1 as a marker of renal pathology activity index in lupus nephritis. Arthritis Res Ther 2012; 14: R164. 10.1186/ar3912 Singh S Wu T Xie C Vanarsa K Han J Mahajan T et al. Urine VCAM-1 as a marker of renal pathology activity index in lupus nephritis Arthritis Res Ther 2012 14 R164 39 Wu T, Fu Y, Brekken D, Yan M, Zhou XJ, Vanarsa K, et al . Urine proteome scans uncover total urinary protease, prostaglandin D synthase, serum

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The Effects of Homocysteine Level in the Critically Ill Patient. A Review

Neurol Neurosurg . 2011;113(6):459-463. 22. Agnati LF, Genedani S, Rasio G, et al. Studies on homocysteine plasma levels in Alzheimer’s patients. Relevance for neurodegeneration. J Neural Transm . 2005;112:163-169. 23. Genedania S, Rasiob G, Cortellic P, et al. Studies on Homocysteine and Dehydroepiandrosterone Sulphate Plasma Levels in Alzheimer’s Disease Patients and in Parkinson’s Disease Patients. Neurotox Res . 2004;6(4):327-332. 24. Jami M-S, Pal R, Hoedt E, Neubert T, Larsen JP, Møller SG. Proteome analysis reveals roles of L-DOPA in response

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Precision Medicine and its Role in the Treatment of Sepsis: A Personalised View

rearrangements. There are other “omes” zones including epigenome, transcriptome, proteome, metabolome though these are less commonly used. These zones contain tremendous information which could be utilised in treating the individual instead of the disease [ 10 ]. Personalised medicine is about using data on multiple scales, and having the ability to create a digital human mapping, with superimposed layers which includes, among other things, social graphs, biosensors, imaging for anatomy description, the characteristics of various “omics” such as genomics, DNA sequencing

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