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Clinical Proteomics in Kidney Disease: From Discovery to Clinical Application

diseases: unraveling the pathophysiology and biomarker discovery. Expert Rev Proteomics. 2005; 2(3): 349-366. 5. Andersen S, Mischak H, Zürbig P et al. Urinary proteome analysis enables assessment of renoprotective treatment in type 2 diabetic patients with microalbuminuria. BMC Nephrol. 2010; 11(1): 29- 6. Stalmach A, Albalat A, Mullen W, and Mischak H. Recent advances in capillary electrophoresis coupled to mass spectrometry for clinical proteomic applications. Electrophoresis. 2013; 34(11): 1452-1464. 7. Pontillo C, Filip S, Borras DM et al. CE

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Increased protein excretion, including albumin, by children of patients with urolithiasis

children, to validate these abnormalities for risk assessment, and to investigate further the urinary proteome and pathophysiology of urolithiasis. Materials and methods The present study, including assent forms for vulnerable participants (those aged 7-12 years, and 13-18 years old) was approved by Institutional Review Board of the Department for Development of Thai Traditional and Alternative Medicine as part of Ministry of Public Health, Thailand (approval No. RLC0029/55), and IRB of Sunpasit Prasong Hospital. We enrolled 116 participants in this study into 4

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Proteomics of the Spermatozoon

-791. 20. Pixton KL, Deeks ED, Flesch FM, et al. Sperm proteome mapping of a patient who experienced failed fertilization at IVF reveals altered expression of at least 20 proteins compared with fertile donors: case report. Hum Reprod. 2004; 19(6): 1438-1447.

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Human Seminal Plasma Proteome Study: a Search for Male Infertility Biomarkers

ABSTRACT

Seminal plasma is a potential source of biomarkers for many disorders of the male reproductive system including male infertility. Knowledge of the peptide and protein components of seminal fluid is accumulating especially with the appearance of highthroughput MS-based techniques. Of special interest in the field of male infertility biomarkers, is the identification and characterization of differentially expressed proteins in seminal plasma of men with normal and impaired spermatogenesis. However, the data obtained until now is still quite heterogeneous and with small percentage of overlap between independent studies. Extensive comparative analysis of seminal plasma proteome is still needed in order to establish a potential link between seminal plasma proteins and male infertility.

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Proteomics of heavy metal toxicity in plants

Proteome Res 2009;8:400-17. doi: 10.1021/pr800561r 27. Giordano PM, Mortvedt J, Mays A. Effect of municipal wastes on crop yields and uptake of heavy metals. J Environ Q u a l 1 9 7 5 ; 4 : 3 9 4 - 9 . d o i : 1 0 . 2 1 3 4 / jeq1975.00472425000400030024x 28. Islam E, Yang X, He Z, Mahmood Q. Assessing potential dietary toxicity of heavy metals in selected vegetables and food crops. J Zhejiang Univ Sci B 2007;8:1-13. doi: 10.1631/ jzus.2007.B0001 29. Fu J, Zhou Q, Liu J, Liu W, Wang T, Zhang Q, Jiang G. High levels of heavy

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Cadmium and zinc induced similar changes in protein and glycoprotein patterns in tobacco (nicotiana tabacum l.) seedlings and plants

spectrometry. Croat Chem Acta 2005;78: 463-77. 25. Balen B, Krsnik-Rasol M, Zamfir AD, Milošević J, Vakhrushev SY, Peter-Katalinić J. Glycoproteomic survey of Mammillaria gracillis tissues grown in vitro . J Proteome Res 2006;5:1658-66. 26. Balen B, Krsnik-Rasol M, Zamfi r AD, Zadro I, Vakhrushev SY, Peter-Katalinić J. Assessment of N-glycan heterogeneity of cactus glycoproteins by one-dimensional gel electrophoresis and matrix-assisted laser desorption/ionization time-of-fl ight mass spectrometry. J Biomol Tech 2007

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Non Invasive Prenatal Diagnosis of Aneuploidy: Next Generation Sequencing or Fetal DNA Enrichment?

. J Proteome Res. 2007; 6: 1245-1257. 57. Kolla V, Jenö P, Moes S, et al. Quantitative proteomics analysis of maternal plasma in Down syndrome pregnancies using isobaric tagging reagent (iTRAQ). J Biomed Biotechnol. 2010; 2010: 952047 [Epub 2009 Nov 5]. 58. Heywood WE, Madgett TE, Wang D, et al. 2D-DIGE analysis of maternal plasma for potential biomarkers for Down syndrome. Proteome Sci. 2011; 9: 56. 59. Heywood WE, Mills K, Wang D, et al. Identification of new biomarkers for Down’s syndrome in maternal plasma. J

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3-nitrotyrosine levels in dichlorvos-induced neurotoxicity

, and proteomics methods for the identification of tyrosine-nitrated proteins. J Proteome Res 2009;8:3222-38. doi: 10.1021/pr900039c 7. Ischiropoulos H, Beckman JS. Oxidative stress and nitration in neurodegeneration: cause, effect, or association? J Clin Invest 2003;111:163-9. doi: 10.1172/JCI17638 8. Althaus JS, Schmidt KR, Fountain ST, Tseng MT, Carroll RT, Galatsis P, Hall ED. LC-MS/MS detection of peroxynitrite-derived 3-nitrotyrosine in rat microvessels.Free Radic Biol Med 2000;29:1085-95. PMID: 11121715 9. He Y

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Determination of Free Doxycycline Concentrations in the Plasma and Milk of Sheep and in the Plasma of Rabbits by using the HPLC Method

. Acta Vet et Zootechnica Sinica. 42 (10): 1438–1444. 14. Castro, L. J., Sahagun, A. M., Diez, M. J., Fernandez, N., Sierra, M., Garcia, J. J. (2009). Pharmacokinetics of doxycycline in sheep after intravenous and oral administration. Vet J. 180, 389–395. https://doi.org/10.1016/j.tvjl.2008.02.001 PMid:18440843 15. Zellner, M., Winkler, W., Hayden, H., Diestinger, M., Eliasen, M., Gesslbauer, B., et al. (2005). Quantitative validation of different protein precipitation methods in proteome analysis of blood platelets. Electrophoresis 26, 2481–2489. https

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Mutation in Phospholipase C, δ1 (PLCD1) gene underlies hereditary leukonychia in a Pashtun family and review of the literature

splicing event, underlies autosomal recessive leuconychia Br J Dermatol 2012 167 4 946 – 949 7 Molecular Operating Environment (MOE), 2013.08; Chemical Computing Group Inc., Montreal, QC, Canada, 2016. Molecular Operating Environment (MOE) 2013.08 Chemical Computing Group Inc Montreal, QC, Canada 2016 8 Rice RH, Xia Y, Alvarado RJ, Phinney BS. Proteomic analysis of human nail plate. J Proteome Res. 2010; 9(12): 6752-6758. 10.1021/pr1009349 Rice RH Xia Y Alvarado RJ Phinney BS Proteomic analysis of human nail plate J Proteome Res 2010 9

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