Víctor M. Pérez-García, Susan Fitzpatrick, Luis A. Pérez-Romasanta, Milica Pesic, Philippe Schucht, Estanislao Arana and Pilar Sánchez-Gómez
.g. [ 55 , 56 ] for brain tumors). From the mathematical point of view it is necessary to define meaningful and robust measures of volumes, geometries, textures, etc., to be computed on images providing biomarkers of clinical relevance. Also, images are to be used as initial data for predictive mathematical algorithms able to simulate tumor evolution and provide therapy personalization.
Another source of information are blood tests, which allow clinically relevant biomarkers (such as e.g. PSA levels in prostatecancer) to be directly measured. In recent years the