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An Overview of Disease Burden, Mechanism, Traditional and Non-traditional Management of Type 2 Diabetes

. Cleveland Clinic. Diabetes Mellitus: An Overview: Management and Treatment. 19. Sjöström L, Peltonen M, Jacobson P, et al. Association of bariatric surgery with long-term remission of type 2 diabetes and with microvascular and macrovascular complications. JAMA . 2014;311:2297-2304. 20. Thaler JP, Cummings DE. Hormonal and metabolic mechanisms of diabetes remission after gastrointestinal surgery. Endocrinology . 2009;150:2518-2525. 21. Keidar A

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The Management of Staphylococcal Toxic Shock Syndrome. A Case Report

R eferences 1. Silversides JA, Lappin E, Ferguson AJ. Staphylococcal Toxic Shock Syndrome: Mechanisms and Management. Curr Infect Dis Rep. 2010;12:392-400. 2. Amagai M, Yamaguchi T, Hanakawa Y, Nishifuji K, Sugai M, Stanley JR. Staphylococcal exfoliative toxin B specifically cleaves desmoglein. J Invest Dermatol. 2002;118:845-50. 3. Hanakawa Y, Stanley JR. Mechanisms of blister formation by staphylococcal toxins. J Biochem. 2004;136:747-50. 4. Ladhani S. Understanding the mechanism of action of the exfoliative toxins of Staphylococcus

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Health Care Professional’s Attitude Towards the Effective Management of Pain in the Critically Ill Neonate

. JAMA. 2008;300:60-70. 8. Gallo AM. The fifth vital sign: implementation of the Neonatal Infant Pain Scale. J Obstet Gynecol Neonatal Nurs. 2003;32:199-206. 9. Bellu R, de Waal KA, Zanini R. Opioids for neonates receiving mechanical ventilation. Cochrane Database Sys Rev 2008;(1):CD004212. 10. Carbajal R, Gall O, Annequin D. Pain management in neonates. Expert Rev Neurother. 2004;4:491-505. 11. Polkki T, Korhonen A, Laukkala H, Saarela T, Vehvilainen-Julkunen K, Pietila AM. Nurses’ attitudes and perceptions of pain assessment in neonatal

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Review. Perioperative Management of Lactic Acidosis in End-Stage Liver Disease Patient

septic shock. Crit Care Med 1991;19:1395-1400. 40. Pascoe PJ, Ilkiw JE, Pypendop BH. Effects of increasing infusion rates of dopamine, dobutamine, epinephrine, and phenylephrine in healthy anesthetized cats. Am J Vet Res. 2006;67:1491-9. 41. Mandell MS, Katz JJ, Wachs M, et al. Circulatory pathophysiology and options in hemodynamic management during adult liver transplantation. Liver Transpl Surg 1997;3: 379-387. 42. Vitin AA, Martay K, Vater Y, et al. Effects of Vasoactive Agents on Blood Loss and Transfusion

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Improving Clinical Performance of an Interprofessional Emergency Medical Team through a One-day Crisis Resource Management Training

R eferences 1. Rovamo L, Nurmi E, Mattila MM, et al. Effect of a simulation-based workshop on the multidisciplinary teamwork of newborn emergencies: an interventional study. BMC Res Notes. 2015;8:671. 2. Hicks MC, Kiss A, Bandiera WG, et al. Crisis Resources for Emergency Workers (CREW II): results of a pilot study and simulation-based crisis resource management course for emergency medicine residents. CJEM. 2012;14(6):354-62. 3. Petrosoniak A, Hicks CM. Beyond crisis resource management: new frontiers in human factors training for acute care

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Post Autologous Stem Cell Transplantation Complication Management in Case of Malignant Lymphoma Patients


Introduction: Autologous hematopoietic stem cell transplantation (ASCT) represents a standard therapy in the management of hematologic malignancies such as malignant lymphomas and has used for approximately three decades. The aim of this study was to determine the occurring post-ASCT complications and their impact on the patients’ recovery for a better management.

Material and methods: An observational retrospective study was performed during a five-year period between 2012 and 2017, involving 58 classical Hodgkin lymphoma and 36 non-Hodgkin lymphoma patients, who underwent ASCT in the Bone Marrow Transplantation Unit of Tîrgu Mureş. The main analyzed complications were: infections, bleeding, hydroelectrolytic disorders, and hypoalbuminemia.

Results: After data analysis we found that 17 patients (18%) presented microbiologically confirmed infection, 10 patients (11%) presented clinically non-significant bleeding, 39 patients (42%) presented electrolyte disorders, and 33 patients (36%) presented hypoalbuminemia, obtaining a positive correlation between the rate of adverse events after ASCT with age (r = 0.9914, p = 0.0009) and the average hospitalization period (r = 1, p <0.00001).

Conclusions: The identification of adverse events and their correlation with the patients’ clinical outcome can lead to better patient management and a faster recovery after ASCT.

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Management of exposed pacemaker caused by burns

References 1. Bonawitz SC. Management of exposure of cardiac pacemaker systems. Ann Plast Surg 2012; 69: 292-295. doi: 10.1097/SAP.0b013e31822350cc 2. Zhan C, Baine WB, Sedrakyan A, Steiner C. Cardiac device implantation in the United States from 1997 to 2004: a population-based analysis. J Gen Intern Med 2008; 23 Suppl 1: 13-19. doi: 10.1007/s11606-007-0392-0 3. Greenspon AJ, Patel JD, Lau E, Ochoa JA, Frisch DR, Ho RT, et al. Trends in permanent pacemaker implantation in the United States from 1993 to 2009: increasing complexity of patients

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Management of bimalleolar fracture in pregnancy

fracture. Orthop Clin North Am. 2012; 43:521-7. 17. Rhee PC, Dennison DG, Kakar S. Avoiding and treating perioperative complications of distal radius fractures. Hand Clin. 2012; 28:185-98. 18. Mehta SS, Rees K, Cutler L, Mangwani J. Understanding risks and complications in the management of ankle fractures. Indian Journal of Orthopaedics. 2014; 48(5):445–452. 19. Patil S, Gandhi J, Curzon I, Hui AC. Incidence of deep-vein thrombosis in patients with fractures of the ankle treated in a plaster cast. J Bone Joint Surg Br. 2007; 89:1340–3. 20

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Perioperative management of patients with pre-excitation syndromes

management of the preexcitation syndromes. Curr Probl Cardiol 1988; 13: 225-310. doi: 10.1016/0146-2806(88)90025-4 5. Öhnell RF. Pre-excitation, cardiac abnormality, pathophysiological, patho-anatomical and clinical studies of excitatory spread phenomenon bearing upon the problem of the WPW (Wolff, Parkinson, and White) electrocardiogram and paroxysmal tachycardia. Acta Med Scand 1944; 152: 1-167 6. Mark DG, Brady WJ, Pines JM. Preexcitation syndromes: diagnostic consideration in the ED. Am J Emerg Med 2009; 27: 878-888. doi: 10.1016/j

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Epistaxis management - our point of view and literature review

REFERENCES 1. Daudia A, Jaiswal V, Jones NS. Guidelines for the management of idiopathic epistaxis in adults: how we do it. Clinical Otolaryngol. 2008;33(6):618–20. DOI:10.1111/j.1749-4486.2008.01795.x. 2. Paul J, Kanotra SP, Kanotra S. Endoscopic Management of Posterior Epistaxis. Indian J Otolaryngol Head Neck Surg. 2011;63(2):141-4. DOI: 10.1007/s12070-010-0054-0. 3. Pond F, Sizeland A. Epistaxis strategies for management. Australian Family Physician. 2000;29(10):933-8. 4. Beran M, Petruson B. Occurrence of epistaxis in habitual nose

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