1. Bessen , H. A. Therapeutic and toxic effects of digitalis: William Withering, 1785. - J. Emerg. Med., 4, 1986, № 3, 243.
2. Bourgeois , B., P. Incagnoli, J. Hanna etV. Tirard. Traitement par anticorps antidigitalique d’une intoxication volontaire par laurier rose. - Annales Françaises d’Anesthésie et de Réanimation, 24, 2005, № 6, 640-642.
3. Camphausen , C., N. A. Haas et A. C. Mattke. Successful treatment of oleander intoxication (cardiac glycosides) with digoxin-specifi c Fab antibody fragments
Burcu Sen-Utsukarci, Turgut Taskin, Fatih Goger, Nurhayat Tabanca, Alden S. Estep, Sonja M. Kessler, Ozlem Akbal-Dagistan, Hilal Bardakci, Mine Kurkcuoglu, James Becnel, Alexandra Kiemer and Afife Mat
;24:315–8. doi: 10.2987/5642.1
17. Tan Y-Z, Yong Y, Dong Y-H, Wang R-J, Li H-X, Zhang H, Guo D-L, Zhang S-J, Dong X-P, Xie X-F. A new secoiridoid glycoside and a new sesquiterpenoid glycoside from Valeriana jatamansi with neuroprotective activity. Phytochem Lett 2016;17:177–80. doi: 10.1016/j.phytol.2016.07.020
18. Bardakçı H, Demirci B, Yeşilada E, Kırmızıbekmez H, Başer, KHC. Chemical composition of the essential oil of the subterranean parts of Valeriana alliariifolia . Rec Nat Prod 2012;6:89–92.
19. Özgökçe F. Özçelik H. Ethnobotanical aspects of some
Karlo Jurica, Irena Brčić Karačonji, Sandra Šegan, Dušanka Milojković Opsenica and Dario Kremer
The phenolic glycoside arbutin and its metabolite with uroantiseptic activity hydroquinone occur naturally in the leaves of various medicinal plants and spices. In this study, an extraction procedure coupled with gas chromatography-mass spectrometry (GC-MS) was developed to determine arbutin and hydroquinone content in strawberry tree (Arbutus unedo L., Ericaceae) leaves. The method showed good linearity (R2>0.9987) in the tested concentration range (0.5-200 μg mL-1), as well as good precision (RSD<5 %), analytical recovery (96.2-98.0 %), and sensitivity (limit of detection=0.009 and 0.004 μg mL-1 for arbutin and hydroquinone, respectively). The results obtained by the validated GC-MS method corresponded well to those obtained by high performance liquid chromatography (HPLC) method. The proposed method was then applied for determining arbutin and hydroquinone content in methanolic leaf extracts. The amount of arbutin in the leaves collected on the island of Koločep (6.82 mg g-1 dry weight) was found to be higher (tpaired=43.57, tc=2.92) in comparison to the amount of arbutin in the leaves collected on the island of Mali Lošinj (2.75 mg g-1 dry weight). Hydroquinone was not detected in any of the samples. The analytical features of the proposed GC-MS method demonstrated that arbutin and hydroquinone could be determined alternatively by gas chromatography. Due to its wide concentration range, the method could also be suitable for arbutin and hydroquinone analysis in leaves of other plant families (Rosaceae, Lamiaceae, etc.).
Damir Sirovina, Nada Oršolić, Gordana Gregorović and Marijana Zovko Končić
Food Chem 2011;125:288-306. doi: 10.1016/j. foodchem.2010.08.012
10. Felgines C, Texier O, Morand C, Manach C, Scalbert A, Régerat F, Rémésy C. Bioavailability of the flavanone naringenin and its glycosides in rats. Am J Physiol Gastrointest Liver Physiol 2000;279:G1148-54. PMID:11093936
11. Yue KK, Chung WS, Leung AW, Cheng C. Redox changes precede the occurrence of oxidative stress in eyes and aorta, but not in kidneys of diabetic rats. Life Sci 2003;73:2557-70. doi: 10.1016/S0024-3205(03)00662-3
12. Obrosova IG
Marija Kovač, Drago Šubarić, Mateja Bulaić, Tihomir Kovač and Bojan Šarkanj
zearalenone-glycoside, a masked mycotoxin, during digestion in swine. J Vet Med B 1990;37:236-40. doi: 10.1111/j.1439-0450.1990.tb01052.x
88. Veršilovskis A, Geys J, Huybrechts B, Goossens E, De Saeger S, Callebaut A. Simultaneous determination of masked forms of deoxynivalenol and zearalenone after oral dosing in rats by LC-MS/MS. World Mycotoxin J 2012;5:303-18. doi: 10.3920/WMJ2012.1411
89. Nagl V, Schwartz H, Krska R, Moll W-D, Knasmüller S, Ritzmann M, Adam G, Berthiller F. Metabolism of the masked mycotoxin deoxynivalenol-3-glucoside
Dušanka Milojković Opsenica, Dražen Lušić and Živoslav Tešić
AOAC Int 2014;97:1259-67. doi: 10.5740/jaoacint.SGEGasic
90. Truchado P, Ferreres F, Tomas-Barberan FA. Liquid chromatography-tandem mass spectrometry reveals the widespread occurrence of flavonoid glycosides in honey, and their potential as floral origin markers. J Chromatogr A 2009;1216:7241-8. doi: 10.1016/j.chroma.2009.07.057
91. Association of Analytical Communities (AOAC) official methods of analysis method 998.12: C-4 plant sugars in honey, internal standard stable carbon isotope ratio method. AOAC Int. Gaithersburg MD (USA
loss individuals are indicated by filled symbols. The arrow denotes the proband. Asterisks denote individuals who have a family history of exposure to amino glycosides.
Analysis of the Mutations in the Mitochondrial Genome
Genomic DNA was isolated from whole blood of participants using the Puregene DNA Isolation Kits (Gentra Systems, Minneapolis, MN, USA). First, three matrilineal relatives (I-2, II-5, III-2) and control subject’s DNA fragments spanning the mitochondrial 12S rRNA and tRNA Ser(UCN) genes were amplified by polymerase chain reaction
Hamidreza Mohammadi, Nasrin Ghassemi-Barghi, Obeid Malakshah and Sorour Ashari
to deltamethrin; a possible mechanism association with oxidative stress, acetylcholinesterase and ATPase. Biomed Prev Nutr 2014;4:527–33. doi: 10.1016/j.bionut.2014.08.006
54. Mani VM, Asha S, Sadiq AMM. Pyrethroid deltamethrin-induced developmental neurodegenerative cerebral injury and ameliorating effect of dietary glycoside naringin in male wistar rats. Biomed Aging Pathol 2014;4:1–8. doi: 10.1016/j.biomag.2013.11.001
55. Khan AM, Sultana M, Raina R, Dubey N, Verma PK. Effect of sub-acute oral exposure of bifenthrin on biochemical parameters in
Asif Ahmed Kibria, Kamrunnessa, Md. Mahmudur Rahman and Annanya Kar
Banana plants (Musa paradaisica) and banana peels (Musa sapientum) two of same genus Musa are grown in worldwide and consumed as ripe fruit or used for culinary purpose. All parts of the banana plants have medicinal applications. The aim of the present study was detection of phytochemicals from this two types of samples and find out some viable phytochemicals which might be used as food additives after commercial purification. These two types of samples banana plants and banana peels were collected from local area of sobhanbagh near Daffodil International University. Samples were washed and dried in room temperature and grinded in pestle. Then 25 gm of grinded samples were soaked in 75 ml of 70% methanol, ethanol, acetone and 0.9% NaCl solution for 72 hours. Then all the extracts of banana peels and banana plants were detected by standard protocol. Flavonoids, carbohydrates, reducing sugar, tannins, saponins, anthraquinones, steroids, glycosides, phytosterols, phenols, terpenoids, were detected from those extracts. Negative and positive result of presence of phytochemicals were detected by the observing of color change. Banana peels and banana plant extracts were showed maximum result in ethanolic extracts. The present study showed qualitative analysis of phytochemicals content existence in banana peels and banana plants extracts. The study also discussed the application of some phytochemicals in food industry.