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Uncommon Finding of a Gastrointestinal Stromal Tumor in a Patient with Hyperechoic Liver Lesions - Case Report

References 1. Liu J, Wang D, Li H, et al - Clinical value of contrast-enhanced ultrasound in diagnosis of hyperechoic liver lesions. Med Sci Monit. 2015; 21:2845 2. Casali PG, Blay JY - ESMO/CONTICANET/EUROBONET Consensus Panel of Experts. Gastrointestinal stromal tumours: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann Oncol. 2010; 21:98-102 3. Søreide K, Sandvik OM, Søreide JA, Giljaca V, Jureckova A, Bulusu VR - Global epidemiology of gastrointestinal stromal tumours (GIST): A systematic review of population

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Coexistence of Multiple Gastrointestinal Stromal Tumors and Signet Ring Cell Carcinoma of Stomach in a Patient with Neurofibromatosis Type-1: Case Report / Nörofibromatozis Tip-1’li Hastada Multipl Gastrointestinal Stromal Tümör ve Midede Taşlı Yüzük Hücreli Karsinom Birlikteliği: Olgu Sunumu

. Rev Esp Enferm Dig 2010, 102: 489-497 9. Kinoshita K, Hirota S, Isozaki K, Ohashi A, Nishida T, Kitamura Y, Shinomura Y, Matsuzawa Y: Absence of c-kit gene mutations in gastrointestinal stromal tumours from neurofibromatosis type 1 patients. J Pathol 2004, 202: 80-85 10. Yantiss RK, Rosenberg AE, Sarran L, Besmer P, Antonescu CR: Multiple gastrointestinal stromal tumors in type I neurofibromatosis: A pathologic and molecular study. Mod Pathol 2005, 18: 475-484 11. Maruta H, Burgess AW: Regulation of the Ras

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Surgical Risk Factors of Patients with Operable Gist

Surg Oncol 2011, 9:13 8. Unalp HR, Erdinc K HD, AliB, Ercument T, Mehmet O. Gastrointestinal stromal tumours: outcomes of surgical management and analysis of prognostic variables. Can J Surg, 52 9. Pleşea IE, Chiuţu L, Bordu SI, Georgescu I, Georgescu EF, Ciobanu D, Mărgăritescu ND, Comănescu V, Nemeş R. Gastrointestinal stromal tumors- a clinical-morphological study on 15 cases. Rom J Morphol Embryol 2014;55:513-523. 10. Zhen H, Yuan Li, Hong Z, Jian Z, Jian C. Prognostic factors and clinicopathological characteristics of small gastrointestinal

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Synchronous Occurrence of Ileal Stromal Tumor (GIST) and Colonic Adenocarcinoma: A Case Report/ Синхроно Јавување На Илеален Стромален Тумор (Гист) И Аденокарцином На Колон – Приказ На Случај

References 1. Hsiao H. H, Sheau-Fang Yang S. F, Liu Y. C, Yang M. J, Lin S. F. Synchronous gastrointestinal stromal tumor and adenocarcinoma at the gastroesophageal junction. Med Sci. 2009; 25(6): 338-41. 2. Nakamura S, Aoyagi K, Iwanaga S, et al. Synchronous and metachronous primary gastric lymphoma and adenocarcinoma: a clinicopathological study of 12 patients. Cancer. 1997; 79(6): 1077-85. 3. Liu S. W, Chen G. H, Hsieh P. P. Collision tumor of the stomach. J Clin Gastroenterol. 2002; 35(4): 332

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Gastrointestinal Stromal Tümörü Taklit Eden Gossypiboma (Tekstiloma): Olgu Sunumu/ A Gossypiboma (Textiloma) Mimicking a Gastrointestinal Stromal Tumor: A Case Report

;122-4. 4. Yamamura N, Nakajima K, Takahashi T, Uemura M, Nishitani A, Souma Y, Nishida T. Intra-abdominal textiloma. A retained surgical sponge mimicking a gastric gastrointestinal stromal tumor: Report of a case. Surg Today. 2008;38:552-4. 5. Patil KK, Patil SK, Gorad KP, Panchal AH, Arora SS, Gautam RP. Intraluminal migration of surgical sponge: Gossypiboma. Saudi J Gastroenterol. 2010;16:221-2. 6. McIntyre LK, Jurkovich GJ, Gunn ML, Maier RV. Gossypiboma: Tales of lost sponges and lessons learned. Arch Surg. 2010;145: 770-5.

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Extra-Gastrointestinal retroperitoneal giant stromal tumor complicated with intra-tumoral hemorrhage: case report and literature review

References 1. Stamatakos, M., Douzinas, E., Stefanaki, C., Safioleas, P., Polyzou, E., Levidou, G. & Safioleas, M., (2009). Gastrointestinal stromal tumor - Review. World Journal of Surgical Oncology. 7, 61. DOI:10.1186/1477-7819-7-61 2. Joensuu, H. (2006). Gastrointestinal stromal tumor (GIST). Annals of Oncology. 17(10), 280-286 3. Kim, K.M., Kang, D.W., Moon, W.S., Park, J.B., Park, C.K., Sohn, J.H., Jeong, J.S., Cho, M.Y., Jin, S.Y., Choi, J.S. & Kang, D.Y. (2005). Gastrointestinal Stromal Tumor Committee

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Imatinib-induced subclinical liver injury: histological changes of non-tumorous hepatic parenchyma

References 1. Demetri GD, von Mehren M, Blanke CD, Van den Abbeele AD, Eisenberg B, Roberts PJ, et al. Efficacy and safety of imatinib mesylate in advanced gastrointestinal stromal tumors. N Engl J Med. 2002; 347:472-80. 2. Schwetz BA. New Treatment for Chronic Myelogenous Leukemia. JAMA. 2001; 286:35. 3. Cohen MH, Williams G, Johnson JR, Duan J, Gobburu J, Rahman A, et al. Approval summary for imatinib mesylate capsules in the treatment of chronic myelogenous leukemia. Clin Cancer Res. 2002; 8: 935

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Spindle Cell Rhabdomyosarcoma Displaying CD34 Positivity: A Potential Diagnostic Pitfall; Report of Two Pediatric Cases / CD34 Pozitivitesi Gösteren İğsi Hücreli Rabdomyosarkoma: İki Pediatrik Tuzak Olgunun Sunumu


Spindle cell rhabdomyosarcoma is a rare subtype of rhabdomyosarcoma mainly seen in children. Occasional aberrant staining with a variety of immunohistochemical markers has been noted. The aberrantly expressed markers include alpha-smooth muscle actin, cytokeratin, S100, neurofilaments, CD20, immunoglobins, and CD117. We report herein two pediatric cases displaying strong CD34 positivity and one with additional focal CD117 positivity, causing considerable difficulty in distinction from solitary fibrous tumor and extra-gastrointestinal stromal tumor. To our knowledge, CD34 staining has been merely reported in rhabdomyosarcoma. Spindle cell rhabdomyosarcoma has to be considered in the differential diagnosis of childhood spindle cell tumors. Post-chemotherapy specimens should be evaluated in caution, since chemotherapy can cause considerable changes in tumor antigen expression. Since CD117 and CD34 are stem cell markers, their positivity in pediatric tumors should be interpreted with caution. Even if the morphology is not supportive, a wide immunohistochemical panel should be applied in childhood malignant solid tumors

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Myxoid liposarcoma with gastric localisation – Case Report

7. Weiss, S.W. & Goldblum, J.R. (2008). Soft tissue tumors (5th edition) (pp. 312-1080). Mosby Elsevier 8. Miettinen, M. & Lasota, J. (2006). Gastrointestinal stromal tumors: review on morphology, molecular pathology, prognosis and differential diagnosis. Arch Pathol Lab Med . 130(10), 1466-1478. PMID:17090188 [PubMed - indexed for MEDLINE] 9. Bosman, F.T., Carneiro, F, Hruban, R.H. & Theise, N.D. (2010). WHO Classification of Tumours of the Digestive System (4th edition). World Health Organization

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Laboratory Tests in Diagnosis of Mastocytosis: Literature Review and Case Report

and determining aggressive course of the disease ( 32 , 37 ). In fact, several other somatic mutations in TET2, SRSF2, ASXL1, CBL, RUNX1 and RAS in patients with SM-AHN, ASM, MCL were detected ( 5 , 24 ). Non-KIT mutations in SM-AHN are found not only in MCs, but also in other myeloid cells, CD34-progenitor cells and sometimes in monocytes and B-lymphocytes ( 1 , 38 , 39 ). However, KIT mutations are found in other neoplasms, including gastrointestinal stromal tumors, acute myeloblastosis, lymphomas and seminomas ( 1 , 2 , 20 ). In addition to the

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