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Evaluation of the Efficiency of 2 Types of Periodontal Probing

pockets. International Journal of Periodontics & Restorative Dentistry , 1993; 13:520-529. 8. Mullally BH, Linden GJ . Comparative reproducibility of proximal probing depth using electronic pressure-controlled and hand probing. J Clin Periodontol , 1994; 21:284-288. 9. Martu A, Nitescu D, Nicolaiciuc O, Popa C, Stefanache T, Ursarescu I, Solomon S, Martu S . Comparative study on the efficiency of periodontal probing with electronic periodontal probe versus conventional periodontal probe. Int J Medical Dentistry , 2014; 18(4):309-312.

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Sinking Skin Flap Syndrome and Paradoxical Herniation Provoked by a Malfunction of External Lumbar Drainage and CSF Leak

REFERENCES 1. Mraček J. Dekompresivní kraniektomie. Praha: Galén; 2016. 2. Hanko M, Richterová R, Kolarovszki B. Efficiency and Limitations of Decompressive Craniectomy in Patients after Traumatic Brain Injury – Preliminary Results. Acta Medica Martiniana 2017; 17(3):32-38. 3. Akins PT, Guppy KH. Sinking Skin Flaps, Paradoxical Herniation, and External Brain Tamponade: A Review of Decompressive Craniectomy Management. Neurocrit Care 2008; 9(2):267-276. 4. Dujovny M et al. Cranioplasty: Cosmetic or Therapeutic? Surg Neurol 1997; 47

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Efficiency and Limitations of Decompressive Craniectomy in Patients after Traumatic Brain Injury – Preliminary Results


Introduction: Decompressive craniectomy (DC) has been recently proven effective tier II therapeutic procedure in the treatment of refractory posttraumatic intracranial hypertension. However, its full potential and effectivity is yet to be described and this surgery remains controversial. The goals of our study include analysis of efficiency of DC and description of risk factors associated with unfavourable outcome.

Methods: 24 patients who underwent DC at the Clinic of Neurosurgery, JFM CU in Martin, during years 2015–2016 were prospectively observed. Selected demographic, clinical, and radiographic factors were analysed and compared with patient’s GOS (Glasgow Outcome Scale) at the time of their first ambulatory control (after 3.5 months in average).

Results: We observed mortality of 29.17 %. Good outcome (GOS 4–5) was achieved by 29.17 % of the patients as well. Preoperative GCS ≤ 5 (p = 0.049), intraventricular bleeding (p = 0.0268), midline shift ≥ 15 mm (p = 0.0067), and the volume of intracranial lesion (R = −0.41, p = 0.046), especially its extracerebral component (R = −0.46, p = 0.02), were identified as statistically significant negative prognostic factors.

Conclusion: DC is effective in the management of patients with traumatic brain injury. Good outcome is achieved by 29.17 % of the patients. Described negative prognostic factors (preoperative GCS ≤ 5, intraventricular bleeding, midline shift ≥ 15 mm, and increasing the volume of traumatic mass lesion) could help in targeting this surgery only to patients who are expected to benefit from it.

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Comparison of 3D MRI with high sampling efficiency and 2D multiplanar MRI for contouring in cervix cancer brachytherapy

-spin-echo sequence with high sampling efficiency (SPACE) for high spatial resolution imaging: initial clinical experiences. Invest Radiol 2005; 40 : 754-60. Fütterer JJ, Yakar D, Strijk SP, Barentsz JO. Preoperative 3T MR imaging of rectal cancer: local staging accuracy using a two-dimensional and three-dimensional T2-weighted turbo spin echo sequence. Eur J Radiol 2008; 65 : 66-71. Kim H, Lim JS, Choi JY, Park J, Chung YE, Kim MJ, et al. Rectal cancer: comparison of accuracy of local-regional staging with two- and three

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Efficiency of XP Endo Shaper (XPS) and Irrigation Protocol on the Quality of Cleaning the Apical Third of Root Canal: SEM Study


Background/Aim: The aim of this study was to evaluate the efficacy of new rotary NiTi instrument XP- endo SHAPER (XPS) used with two irrigation protocols on the root canal cleaning in the apical area.

Material and Methods: The research was conducted on 30 single-rooted teeth extracted for orthodontic reasons which were divided into the two groups. Instrumentation of the canals was conducted with XPS instrument and 2% solution of NaOCl was used as irrigant. Instrumentation in the first group was performed using a conventional continuous irrigation, in the second group, protocol of final irrigation was performed intermittently in 3 cycles. The SEM analysis of the apical third of the canal was performed on longitudinal root cross-section standardized photomicrography with a magnification of 2000X.

Results: Results showed that a thicker smear layer was observed in the first group and with continuous irrigation protocol (2,10) in relation to the intermittent irrigation protocol in 3 cycles (1,96), but without significant differences.The walls of the root canal in the apical third of the samples of the second group were slightly cleaner (73.3%) in comparison with the teeth of the first group (64, 7%), but also without significant differences.

Conclusions: The use of XPS and 2% solution of NaOCl in the root canal enables efficient cleaning of the apical third of tooth. The final irrigation protocol in three cycles improves the efficiency of the smear layer removal in the apical segment of the canal.

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Total neoadjuvant treatment of locally advanced rectal cancer with high risk factors in Slovenia

or with the presence of EMVI or extramesorectal lymph nodes involvement on magnetic resonance imaging (MRI) were considered candidates for TNT. Later on two more indications for this treatment selection were added: N2 disease and the distance £ 1 mm of tumor or lymph nodes from mesorectal fascia (MRF). The main objective of the present study is to evaluate efficiency and toxicity of TNT treatment in LARC with high risk factors for local or distant recurrence in Slovenia. Patients and methods Patient selection This prospective observational study included

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Dusp6 inhibits epithelial-mesenchymal transition in endometrial adenocarcinoma via ERK signaling pathway

surgery, radiotherapy, chemotherapy and hormone therapy for early-stage diseases. 5 However, therapeutic efficiency of above treatments was extremely limited, hence searching for potential therapeutic targets in EAC become urgent. Tumor suppressive role of dual-specificity phosphatase 6 (DUSP6) in cancers is suggested to act through ERK/MAPK signaling pathway. Intracellular ERK/MAPK signaling pathway is involved in a variety of cancer transformation as well as their tumorigenesis such as breast cancer 10 , lung cancer 11 , ovarian cancer 12 , pancreatic cancer. 13

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Dosimetric study for spine stereotactic body radiation therapy: magnetic resonance guided linear accelerator versus volumetric modulated arc therapy

helical tomotherapy and fixed field IMRT: plan quality, delivery efficiency and accuracy. Med Phys 2010; 37: 1350-9. doi: 10.1118/1.3326965 Rao M Yang W Chen F Sheng K Ye J Mehta V et al Comparison of Elekta VMAT with helical tomotherapy and fixed field IMRT: plan quality, delivery efficiency and accuracy Med Phys 2010 37 1350 9 10.1118/1.3326965 27 Matuszak MM, Yan D, Grills I, Martinez A. Clinical applications of volumetric modulated arc therapy. Int J Radiat Oncol Biol Phys 2010; 77: 608-16. doi: 10.1016/j.ijrobp.2009

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Clinical relevance of the borderline results of the Hybrid Capture 2 High-Risk HPV DNA assay with cervical samples collected in Specimen Transport Medium

intraepithelial neoplasia grade 2 and 3 Eur J Gynaecol Oncol 2012 33 261 4 PMID: 22873095 8 de Cremoux P, Coste J, Sastre-Garau X, Thioux M, Bouillac C, Labbe S, et al. Efficiency of the Hybrid Capture 2 HPV DNA test in cervical cancer screening. A study by the French Society of Clinical Cytology. Am J Clin Pathol 2003; 120: 492-9. doi: 10.1309/XFUC-PP6M-5XUA-94B8 14560561 10.1309/XFUCPP6M5XUA94B8 de Cremoux P Coste J Sastre-Garau X Thioux M Bouillac C Labbe S et al Efficiency of the Hybrid Capture 2 HPV DNA test in cervical cancer screening. A

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Sleep apnea syndrome and heart failure—mechanisms and consequences

therapy ( 58 ) Effects of CPAP therapy in CSA and HF patients was first evaluated in CANPAP study (Canadian Positive Airway Pressure Trial for Patients with Congestive Heart Failure and Central Sleep Apnea) ( 59 ), a large, prospective, multicenter study. Because of poor patients, compliance (about 3.6 h/night) and variable effects with CPAP therapy ( 60 ), a newer therapy was developed, called adaptive pressure support servo-ventilation (ASV), a synchronized form of positive pressure ventilation. Compliance and efficiency of this therapy was followed in several

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