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rate and isoeffect relationship for normal tissue responses. Int J Rad Oncol Biol Phys. 1982; 8: 1981-1997. Dale RG. The application of the linear quadratic dose effect equation to fractionated and protracted radiotherapy. Brit J Radiol. 1985; 58: 515-528. Dale RG. The application of the linear quadratic model to fractionated radiotherapy when there is incomplete normal tissue recovery between fractions and possible implications for treatments involving multiple fractions per day. Brit J Radiol. 1986; 59: 919-927. Fowler JF. The linear quadratic formula and progress

aspiration after chemoradiotherapy for head-and-neck cancer: Which anatomic structures are affected and can they be spared by IMRT. Int J Radiat Oncol Biol Phys. 2004;60(5):1425-1439. [33] Feng FY, Kim HM, Lyden TH, et al. Intensity-modulated radiotherapy of head and neck cancer aiming to reduce dysphagia: Early dose–effect relationships for the swallowing structures. Int J Radiat Oncol Biol Phys. 2007;68(5):1289-1299. [34] Jensen K, Lambertsen K, Grau C. Late swallowing dysfunction and dysphagia after radiotherapy for pharynx cancer: Frequency, intensity and correlation