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obesity, constitute a serious public health issue. Concerning the mechanisms of action of EDCs, many questions remain unanswered. Moreover, nonlinear/non-monotonic action (as opposed to toxic dose-effect), cocktails consisting of EDCs with possible additive or synergistic or antagonistic effects, latency, window of exposure and the possibility of transgenerational effects are under intense scientific discussion. Exposure to EDCs is ubiquitous and can occur during potentially sensitive periods of development that are important in the etiology of childhood

;76(3):407-414. DOI: 10.1007/s00128-006-0936-8. [19] Araújo ASF, Monteiro RTR, Abarkeli RB. Effect of glyphosate on the microbial activity of two Brazilian soil. Chemosphere. 2003;52:799-804. DOI: 10.1016/S0045-6535(03)00266-2. [20] Crouzet O, Batisson I, Besse-Hoggan P, Bonnemoy F, Bardot C, Poly F, et al. Response of soil microbial communities to the herbicide mesotrione: A dose-effect microcosm approach. Soil Biol Biochem. 2010;42:193-202. DOI: 10.1016/j.soilbio.2009.10.016. [21] Kucharski J, Wyszkowska J. Biological properties of soil contaminated with the herbicyde Apyros 75