Rositsa V. Sandeva, Stanislava M. Mihaylova, Gergana N. Sandeva, Katya Y. Trifonova and Ruska D. Popova-Katsarova
. Pharmacol Biochem Behav. 2010;97(1):101-6.
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12. Martines C, Gonzales E, Garcia RS, Salas G, Constantino-Casas F, Macias L et al. Effects on body mass of laboratory rats after
Daniela Y. Arabadzhieva, Zhaneta T. Georgieva, Ara G. Kaprelyan and Zdravko D. Slavov
The aim of the investigation was to analyze the correlation between myocardial infarction and ischemic heart disease, on the one hand, and acute ischemic stroke (AIS), on the other hand. We studied 258 AIS patients (mean age 70.9±7.22 years, range 49-92 years) hospitalized in 2007-2013 in the First Clinic of Neurology, St. Marina University Hospital of Varna. The diagnosis of acute ischemic stroke was confirmed by Doppler sonography and computed tomography of the cerebral circulation. Data were statistically processed by variation and correlation analysis. Our results proved a relatively strong correlation between effort angina pectoris and ischemic heart disease (Pearson's coefficient: r=0.643) as well as a weak correlation between ischemic heart disease and myocardial infarction (Pearson's coefficient: r=0.243) among acute ischemic stroke patients. The well-known risk factors for these cardiovascular diseases such as obesity, tobacco smoking, low physical activity and alcohol abuse were common among the patients with acute ischemic stroke, too. In conclusion, both myocardial infarction and ischemic heart disease are strongly associated with the development of acute ischemic stroke. Such patients require strict and regular control by general practitioners. They should observe an appropriate diet and adhere to a healthy life-style.
Pavlina L. Gidikova, Gergana N. Sandeva, Kamelia H. Haracherova and Rositsa V. Sandeva
A person's weight depends on major factors like genetics, diet, and physical activity. Physical activity in adults is defined mainly by workload – light, moderate or heavy. The aim was to explore associations between weight and chronic non-infectious diseases in workers with different physical activity. The subjects included in the study were 224 male and 249 female employees, divided by workload based on their job description. Body mass index (BMI) and disease incidence were calculated, and statistical analysis was performed. The highest percentage of overweight and obese subjects was found in men with light workload. The mean BMI for men (27.434.85) was significantly higher than that for women (25.875.06). Analysis of obesity-associated diseases showed that in workers with higher BMI there was a higher incidence of endocrine disorders, musculoskeletal and related neurological diseases. Diseases of the circulatory system were highly prevalent in both overweight/obese and underweight employees. In conclusion, physical activity at work contributes to changes in BMI in the working population. Obesity-associated circulatory, endocrine and musculoskeletal diseases were highly prevalent in the groups with higher BMI. The prevalence in employees without diseases was in inverse relation to BMI.
Katerina D. Simeonova, Krassimir D. Dimitrov and Nikolay D. Danchev
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5. Adrian M, Chanut E, Laurant P, Gaume V, Berthelot A. A long-term moderate magnesium-deficient diet aggravates cardiovascular risks associated with aging and increases mortality in rats. J Hypertens. 2008;26(1):44-52.
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Tsvetelina V. Petkova-Marinova, Boryana K. Ruseva and Bisera D. Atanasova
21. Bates CJ, Thane CW, Prentice A, Delves HT. Selenium status and its correlates in a British national diet and nutrition survey: people aged 65 years and over. J Trace Elem Med Biol. 2002;16(1):1-8.
22. Semba RD, Ferrucci L, Cappola AR, Ricks MO, Ray AL, Xue QL, et al. Low serum selenium is associated with anemia among older women living in the community: The Women’s Health and Aging Studies I and II. Biol Trace Elem Res. 2006;112(2):97-107. doi:10.1385/BTER:112:2:97.
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Rositsa V. Sandeva, Stanislava M. Mihaylova and Gergana N. Sandeva
, Perello M, Sakata I, Osborne-Lawrence S, Savitt JM, Lutter M, et al. Ghrelin mediates stress-induced food-reward behavior in mice. J Clin Invest. 2011;121(7): 2684-92.
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Vitamin D - „the sunshine vitamin” is essential for the good functioning of the human body. The most important forms of the vitamin D are the vitamin D2 and the vitamin D3, both biologically inactived. Vitamin D can come from: diet or nutritiv suplimentts and skin. The activation of vitamin D is effect in two steps to the physiologically active 1,25-dihydroxyvitamin D [1,25(OH)2D]. The biological actions of Vitamin D involve regulation of gene expression at the transcriptional level and are mediated through binding to a Vitamin D Receptor (VDR). Vitamin D has multiple roles: hormonale/ nonhormonale, skeletale/nonscheletale, genomice/nongenomice. Interesting is inversely corelation between Vitamin D and total body fat (BMI) and correlation between Vitamin D and cognitive impairment, especially Alzheimer Disease or delirium during hospitalisation. The curent recomandations regarding the supplying with Vitamin D are different for regions of the globe, also differ depending on the baseline serum Vitamin D and on the desired effect. So, potential nonskeletal effects occur at levels >30ng/ml, above 50-75ng/ml, serum level who should become the target of the supplementation. The loading dose should be considered perioperatively for rapid effects. In conclusion, Vitamin D is more than just a vitamin. It is a substance with multiple roles in body’s economy, and in recent years there has been an interest in the relation be tween vitamin D deficiency and obesity or cognitive impairment. The majority of the data supports association, not causation, of low vitamin D levels. In other words, much of data does not clearly support the idea that vitamin D supplementation in a patient with low vitamin D levels reduces the risk of these diseases. But, the supplimentation is very easy and no harm might be done.
. Maraki MI, Panagiotakos B, Jansen LT. Validity of Predictive Equations for Resting Energy Expenditure in Greek Adults. 2018;72701:134–41.
22. Nakajima N, Ito Y, Yokoyama K, Uno A, Kato K, Iwasaki A, et al. The expresssion of Mdm2 on Helicobacter pylori infected intestinal metaplasia and gastric cancer. J Clin Biochem Nutr. 2005;128(4):A401–2.
23. Compher C, Frankenfield D, Keim N, Roth-Yousey L. Best Practice Methods to Apply to Measurement of Resting Metabolic Rate in Adults: A Systematic Review. J Am Diet Assoc. 2006;106(6):881–903.
Robert Ivaşcu, Ligia Torsin, Darius Morlova, Alina Stanca, Mihai Neguţu, Silvius Negoiţă and Mădălina Duţu
Scavenger of Reactive Oxygen Species. In Vivo. 2018;32(2):255–64.
77. Rice TW, Wheeler AP, Thompson BT, de-Boisblanc BP, Steingrub J, Rock P, et al. Enteral omega-3 fatty acid, gamma-linolenic acid, and antioxidant supplementation in acute lung injury. JAMA. 2011 Oct 12;306(14):1574–81.
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