Victoria Ancuța Rus, Florina Ruța, Maria Sălcudean, Monica Tarcea, Costela Șerban, Călin Avram, Iustinian Simion and Theodora Benedek
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Oana-Cristina Cînpeanu, Monica Tarcea, Paul Cojan, Daniel Iorga, Peter Olah and Raquel P.F. Guiné
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of 14.87. This was suggestive of pyruvate dehydrogenase complex deficiency (PDCD) ( Table 1 ). A skeletal muscle biopsy showed low levels of activated PDC and PDC/E3 ratio ( Table 1 ) as well as a pyruvate dehydrogenase and mitochondrial complex panel testing positive for pyruvate dehydrogenase alpha 1 (PDHA1) gene mutation confirming the diagnosis of PDCD.
The patient was given a trial of a ketogenic diet (KD) which did not result in an elevation of lactate levels ( Figure 2 ). He remained on prolonged mechanical ventilation secondary to the development of acute
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Cardiovascular and digestive diseases frequently share the same risk factors such as obesity, unhealthy diet, or several social behaviors, and the increasing prevalence of patients with overlapped cardiovascular and digestive symptoms is a challenging problem in the daily practice. Patients with gastro-esophageal reflux disease can exhibit various forms of chest pain that can be very similar to angina. Furthermore, antithrombotic therapies used for preventive or curative purposes in patients with cardiovascular diseases are frequently associated with gastrointestinal side effects including bleeding. At the same time, in patients with coronary stents presenting to the emergency department with chest pain, angina triggered by stent thrombosis or restenosis should be differentiated from angina-like symptoms caused by a gastrointestinal disease. The aim of this review was to present the complex inter-relation between gastroesophageal diseases and angina in patients on dual antiplatelet therapy following an acute coronary syndrome, with a particular emphasis on the role of anemia resulting from occult or manifest gastrointestinal bleeding, as a precipitating factor for triggering or aggravating angina.
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Alexandra Lazăr, Anca Meda Georgescu, Alexander Vitin and Leonard Azamfirei
Hippocrates, the “Father” of modern medicine, was convinced that disease was a result of multiple factors, including the patient’s lifestyle, environmental forces and diet. Accordingly, as these are unique for every individual, treatment should be focused on the individual. He stated that because the organism acts as one, it should be treated as one, and not as individual parts of a bigger system.
In recent times, a new form of medicine has become increasingly exercised, namely personalised medicine (PM) and is efficacious in many medical
Simona Cernea, Andrada Larisa Roiban and Emőke Both
, Leptin Soluble Receptor, and the Free Leptin Index following a Diet and Physical Activity Lifestyle Intervention in Obese Males and Females. J Obes . 2016;2016:8375828.
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