Marijana Dajak, Svetlana Ignjatović and Nada Majkić-Singh
, Sterner G, et al. Simple cystatin C based prediction equations for glomerular filtration rate compared with the modification of diet in renal disease prediction equation for adults and the Schwartz and the Counahan-Barratt prediction equations for children. Clin Chem 2005; 51: 1420-31.
Tan GD, Lewis AV, James TJ, Altman P, Taylor RP, Levy JC. Clinical usefulness of cystatin C for the estimation of glomerular filtration rate in type 1 diabetes. Diabetes Care 2002; 25: 2004-9.
Clinical and Laboratory Standards
Duygu Aydemir, Ehsan Sarayloo and Nuriye Nuray Ulusu
adipose-like Cells. J Biol Chem 1995; 270: 28183–7. 10.1074/jbc.270.47.28183 7499310
Teboul L Gaillard D Staccini L Inadera H Amri EZ Grimaldi PA Thiazolidinediones and fatty acids convert myogenic cells into adipose-like Cells J Biol Chem 1995 270 28183 7
6 Akbay E, Ulusu NN, Töröner F, Ayvaz G, Taneri F, Aktürk M, et al. Effects of rosiglitazone treatment on the pentose phosphate pathway and glutathione-dependent enzymes in liver and kidney of rats fed a high-fat diet. Curr Ther Res Clin Exp. 2004; 65: 79–89. 10.1016/S0011-393X
medications was obtained from the medical records. At least once per year plasma lipid levels, urea and creatinine and urine albumin and albumin/creatinine ratio were determined. Kidney function was assessed in line with the revised chronic kidney disease classification ( 16 ). Albuminuria was classified as normal (<20 mg/L), moderately increased albuminuria (20–200 mg/L, formerly known as microalbuminuria) and severely increased albuminuria (>200 mg/L, formerly known as macroalbuminuria). Estimated glomerular filtration was calculated according to the Modification of Diet
currently investigated in clinical trials, including obeticholic acid, liraglutide, elafibranor, and aramchol are being evaluated ( 10 ). Lifestyle modification focused on diet and exercises continue to be the primary treatment ( 11 ). The American Association for the Study of Liver Diseases practice guideline suggests the loss of at least 3–5% of body weight to improve steatosis, and up to 10% to improve necroinflammation ( 12 ). However, most patients who ask medical advice have a long history of ineffective attempts at dietary and lifestyle changes ( 13 ). Furthermore
Emina Čolak, Dragana Pap, Ljubinka Nikolić and Sanja Vicković
and hyperglycemia result in accumulation of advanced glycation end products (AGE) which can cause cellular damage by inducing cross-linking of proteins and collagen and promoting alteration of extracellular matrix and vascular function and structure ( 38 , 39 ).
In a clinical study conducted by Bigornia et al. ( 40 ) it has been proved that long-term weight reduction can improve cardiovascular risk by decreasing oxidative stress markers and by increasing antioxidant defense system. Diet regimen containing fruits, green vegetables, whole grains, fish and olive oil
Magdalena Kulus, Blanka Borowiec, Małgorzata Popis, Piotr Celichowski, Michal Jeseta, Dorota Bukowska, Hanna Piotrowska-Kempisty, Małgorzata Bruska, Maciej Zabel, Michał Nowicki, Bartosz Kempisty and Paweł Antosik
inputs, and “---” for predicted FIs
Increasing food demand observed nowadays is connected with the necessity of more efficient acquisition of raw animal materials. Attempts are being made to increase the reproductive capacity of various animal species. Most often, this is achieved through introduction of more caloric diets. The metabolic pathways associated with fat management are also changing. Increasingly, the cause of metabolic disorders is attributed to elevated NEFA levels in the blood. It has also been shown that high values of these fatty
Greg Hutchings, Mariusz J. Nawrocki, Paul Mozdziak and Bartosz Kempisty
CVD is the most prevalent mortality type worldwide, with an approximate 31% of deaths related to some form of CVD in 2016 [ 1 ]. In addition, it is estimated in Europe that CVD is the cause of 45% of deaths per year [ 2 ]. Two of the main risk factors in development of cardiovascular disease are obesity, stemming from poor diet, lack of physical activity, and smoking. These lifestyle choices can lead to hypertension, high blood cholesterol, atherosclerosis, all increasing likelihood of CVD.
The World Health Organisation (WHO) reports that over
normal serum creatinine levels. J Am Soc Nephrol 2002; 13: 2140-44.
Rule AD, Larson TS, Bergstralh EJ, Slezak JM, Jacobsen SJ, Cosio FG. Using serum creatinine to estimate glomerular filtration rate: accuracy in good health and in chronic kidney disease. Ann Intern Med 2004; 141: 929-37.
Poggio ED, Nef PC, Wang X, Greene T, Van Lente T, Dennis VW. Performance of the Cockcroft-Gault and modification of diet in renal disease equations in estimating GFR in ill hospitalized patients. Am J Kidney Dis 2005; 46: 242
Kristel Klaassen, Maja Đordevič, Maja Stojiljkovič Petrov and Sonja Pavlović
(PKU) related to white matter abnormalities or elevated phenylalanine levels? Dev Neuropsychol 2007; 32: 645-68.
3. De Groot MJ, Hoeksma M, Blau N, Reijngoud DJ, van Spronsen FJ. Pathogenesis of cognitive dysfunction in phenylketonuria: review of hypotheses. Mol Genet Metab 2010; 99: Suppl 1: 86-9.
4. Guttler F, Guldberg P. Mutation analysis anticipates diet - ary requirements in phenylketonuria. Eur J Pediatr 2000; 159: Suppl 2: 150-3.
5. Scriver CR, Waters PJ. Monogenic traits are not simple. Trends Genet 1999; 15
Mustafa Kaplan, Ihsan Ates, Mahmut Yüksel, Yasemin Ozderin Ozin, Muhammed Yener Akpinar, Canan Topcuoglu and Ertuğrul Kayaçetin
Background: The objective here is to examine the role of overall oxidative stress in the etiopathogenesis of gluten-sensitive enteropathy disease and its relationship with gluten free diet and autoantibodies.
Methods: Eighty gluten-sensitive enteropathy patients and 80 control group participants were included in the study. As oxidative stress parameters, we researched total antioxidant status (TAS), total oxidant status (TOS), oxidative stress index (OSI), paraoxonase-1 and arylesterase parameters in the serum samples of gluten-sensitive enteropathy patients.
Results: In comparison to the control group, gluten-sensitive enteropathy patients had lower TAS, paraoxonase-1 and arylesterase levels and gluten-sensitive enteropathy patients had considerable TOS and OSI levels. In contrast, patients who agreed to the gluten free eating routine had a higher OSI proportion and patients who did not conform to the gluten free eating regimen had a lower paraoxonase-1 level. An affirming reciprocation was de tected amidst TOS and OSI proportion and gluten-sensitive enteropathy autoantibodies and C-reactive protein levels and a negative correlation was found between arylesterase level and gluten-sensitive enteropathy autoantibodies.
Conclusions: We observed oxidative stress levels to be higher in gluten-sensitive enteropathy patients contrasted with the control group. Oxidative stress level showed differences in gluten-sensitive enteropathy patients depending on gluten diet content and autoantibody positivity. In point of fact, C-reactive protein and gluten-sensitive enteropathy autoantibodies are identified with oxidative anxiety parameters resulting in the possibility that oxidative stress might be successful in the gluten-sensitive enteropathy pathogenesis.