Katarzyna Strawa-Zakoscielna, Monika Lenart-Lipinska, Aneta Szafraniec, Grzegorz Rudzki and Beata Matyjaszek-Matuszek
1. American Diabetes Association: Diagnosis and classification of diabetesmellitus. Diabetes Care, 2014 Jan; 37 Suppl 1: 81-90.
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4. Briana D.D., Malamitsi-Puchner A.: Reviews
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2. Prasad S, Sajja RK, Naik P, Cucullo L. DiabetesMellitus and Blood-Brain Barrier Dysfunction: An Overview. J Pharmacovigil 2014; 2: 125.
3. Chmiel-Perzyńska I, Perzyński A, Urbańska EM. Experimental diabetesmellitus type 1 increases hippocampal content of kynurenic acid in rats. Pharmacol Rep. 2014; 66: 1134-1139.
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Grzegorz Mizerski, Pawel Kicinski and Andrzej Jaroszynski
1. Bhatia K. et al.: Canagliflozin-current status in the treatment of type 2 diabetesmellitus with focus on clinical trial data. World J. Diabetes, 5, 399, 2014.
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Maya P. Danovska, Margarita L. Alexandrova and Irena I. Gencheva
Individuals with hypertension and diabetes mellitus are at high risk of cerebrovascular and cardiovascular morbidity and mortality. Recent advances in the multifactorial pathophysiology of atherogenesis provide important information about the complex interrelations between traditional risk factors, inflammation and oxidative stress in mediating all stages of atherosclerosis. The objective of the study was to determine if some inflammatory and oxidative stress markers in patients with arterial hypertension and diabetes mellitus differ from those in healthy age-matched controls. Our results revealed a significant difference in blood pro/antioxidant activities in hypertensive diabetics and the controls. The investigation of inflammatory and oxidative stress markers along with traditional risk factors proves useful in complex assessment of vascular risk and primary prophylaxis of cerebrovascular and cardiovascular events.
Cyril James, Thankachan V. Attacheril, N. Balakrishnan, Diana K. Gaydarova, Nadya Y. Stancheva, Ivan P. Gerchev, Shreya Ohri and Snezhana T. Tisheva
Coronary artery disease (CAD) is a condition that develops due to accumulation of atherosclerotic plaque in the epicardial coronary arteries, leading to myocardial ischemia. It is the leading cause of death worldwide and is a common complex disease. A study was carried out in a group of 496 patients with acute coronary syndrome or with angiographic or stress test evidence for coronary artery disease, admitted to the Department of Cardiology at Lourdes Heart Institute and Neuro Centre during the period June-August 2012. The risk factors studied were hypertension, diabetes mellitus, dyslipidemia, body mass index, smoking and family history of CAD. The results demonstrated that in both males and females of the Indian population studies, diabetes and dyslipidemia were major risk factors for CAD, while hypertension was not a major risk factor. Therefore, early detection and treatment of diabetes mellitus and dyslipidemia play a vital role in prevention of CAD in Indian population.
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Ginka H. Rayanova, Silvia S. Ganeva, Katya N. Todorova, Tsvetan H. Lukanov and Svetla P. Gecheva
5. Dogru T, Sonmez A, Tasci I, Bozoglu E. Yilmaz MI, Gene H. at al. Plasma resistin levels in patients with newly diagnosed untreated type 2 diabetesmellitus and impaired glucose tolerance. Diabetes Res Clin Pract. 2007;76 (1):2-7.
6. Norata GD, Ongari M, Garlaschelli K, Raselli S, Grigore L, Catapano AL. Plasma resistin levels correlate with determinants of the metabolic syndrome. Eur J Endocrinol. 2007;156(2):279-84.
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Magdalena Halabis, Marcin Dziedzic, Joanna Warchulinska, Iwona Kaznowska-Bystryk and Janusz Solski
tissue. Biochim. Biophys. Acta, 1732, 1-3, 2005.
27. Schaffler A., Zeitoun M., Wobser H. et al.: Frequency and significance of the novel single nucleotide missense polymorphism Val109Asp in humangene encoding omentin in Caucasian patients with type 2 diabetesmellitus or chronic inflammatory bowel disease. Cardiovasc. Diabetol., 6, 3, 2007.
28. Senolt L., Polanska M., Filkova M. et al.: Vaspin and omentin: new adipokines differentially regulated at the site of inflammation in rheumatoid arthritis. Ann. Rheum. Dis., 69, doi:10.1136/ ard
implantation of Wharton’s jelly-derived mesenchymal stem cells from the umbilical cord for newly-onset type 1 diabetesmellitus. Endocr J 60(3):347-57, 2013.
22. Introna M., et al.: Treatment of graft versus host disease with mesenchymal stromal cells: a phase I study on 40 adult and pediatric patients. Biol Blood Marrow Transplant. 20(3):375-81, 2014. doi: 10.1016/j.bbmt.2013.11.033.
23. Jin J.L., et al.: Safety and efficacy of umbilical cord mesenchymal stem cell therapy in hereditary spinocerebellar ataxia. Curr Neurovasc Res 10