Emilia Rymkiewicz, Agata Rękas-Wójcik, Sylwia Milaniuk, Barbara Mosiewicz and Grzegorz Dzida
Antypsychotics and New Onset DiabetesMellitus: An Overview of the Literature. Pharmacopsychiatry. 2004;37(1):1-11.
5. Sinclair A. Special Considerations in Older Adults with Diabetes: Meeting the Challenge. Diabetes Spectr. 2006;19:229-33.
6. Inouye S, Studenski S, Tinetti M, Kuchel G. Geriatric Syndromes: Clinical, Research and Policy Implications of a Core Geriatric Concept. J Am Geriatr Soc. 2007;55(5):780-91.
7. Cowie C, Rust K, Byrd-Holt D, et al. Prevalence of Diabetes and Impaired Fasting Glucose in Adults in the U
Grażyna J. Iwanowicz-Palus, Marta Zarajczyk, Aleksandra Jakubowska, Agnieszka Bień and Ewa Rzońca
, Samoiluk O. Jakość życia kobiet z cukrzycą ciążową. Probl Pielęg. 2014;22(4):459-63.
5. Kopacz K, Myśliwiec M, Techmańska I, et al. Cukrzyca ciążowa - narastający problem diagnostyczny i epidemiologiczny. Diabetol Prakt. 2011;12 (3):96-102.
6. Kutowska J, Gierszewska M, Mieczkowska E, et al. Quality of life among women with gestational diabetesmellitus. Med Biol Sci. 2012;26(1):133-8.
7. Kalka D. Poczucie jakości życia a objawy depresji i sposoby radzenia sobie ze stresem u osób z cukrzycą typu 2 - doniesienia wstępne
Maya P. Danovska, Margarita L. Alexandrova and Irena I. Gencheva
Individuals with hypertension and diabetes mellitus are at high risk of cerebrovascular and cardiovascular morbidity and mortality. Recent advances in the multifactorial pathophysiology of atherogenesis provide important information about the complex interrelations between traditional risk factors, inflammation and oxidative stress in mediating all stages of atherosclerosis. The objective of the study was to determine if some inflammatory and oxidative stress markers in patients with arterial hypertension and diabetes mellitus differ from those in healthy age-matched controls. Our results revealed a significant difference in blood pro/antioxidant activities in hypertensive diabetics and the controls. The investigation of inflammatory and oxidative stress markers along with traditional risk factors proves useful in complex assessment of vascular risk and primary prophylaxis of cerebrovascular and cardiovascular events.
Cyril James, Thankachan V. Attacheril, N. Balakrishnan, Diana K. Gaydarova, Nadya Y. Stancheva, Ivan P. Gerchev, Shreya Ohri and Snezhana T. Tisheva
Coronary artery disease (CAD) is a condition that develops due to accumulation of atherosclerotic plaque in the epicardial coronary arteries, leading to myocardial ischemia. It is the leading cause of death worldwide and is a common complex disease. A study was carried out in a group of 496 patients with acute coronary syndrome or with angiographic or stress test evidence for coronary artery disease, admitted to the Department of Cardiology at Lourdes Heart Institute and Neuro Centre during the period June-August 2012. The risk factors studied were hypertension, diabetes mellitus, dyslipidemia, body mass index, smoking and family history of CAD. The results demonstrated that in both males and females of the Indian population studies, diabetes and dyslipidemia were major risk factors for CAD, while hypertension was not a major risk factor. Therefore, early detection and treatment of diabetes mellitus and dyslipidemia play a vital role in prevention of CAD in Indian population.
Ginka H. Rayanova, Silvia S. Ganeva, Katya N. Todorova, Tsvetan H. Lukanov and Svetla P. Gecheva
5. Dogru T, Sonmez A, Tasci I, Bozoglu E. Yilmaz MI, Gene H. at al. Plasma resistin levels in patients with newly diagnosed untreated type 2 diabetesmellitus and impaired glucose tolerance. Diabetes Res Clin Pract. 2007;76 (1):2-7.
6. Norata GD, Ongari M, Garlaschelli K, Raselli S, Grigore L, Catapano AL. Plasma resistin levels correlate with determinants of the metabolic syndrome. Eur J Endocrinol. 2007;156(2):279-84.
7. Utzschneider K, Carr D, Tong J, Wallace T, Hull R, Zrika S at al. Resistin is not associated with
Paulina Gil-Kulik, Alicja Niedojadło, Marcin Feldo, Jolanta Karwat, Lidia Kotuła, Piotr Chomik, Ilona Dudek, Małgorzata Filas, Agnieszka Wojcieszek, Tomasz Zubilewicz, Anna Bogucka-Kocka and Janusz Kocki
Introduction. Recent research shows that programmed cell death has great importance in the pathomechanism of atherosclerosis. The BIRC5 and BIRC6 genes belong to Class III IAPs with the anti-apoptotic effect. The proteins display multidirectional action. According to the available literature, in addition to the effect of apoptosis inhibition they also display other properties. It is suggested that they play an important role in the processes of proliferation and cellular differentiation. Aim. The aim of the study was to assess the expression of the BIRC5 and BIRC6 genes in normal peripheral blood lymphocytes and in peripheral blood lymphocytes of patients diagnosed with atherosclerosis. Material and methods. The analysis was carried out on RNA samples obtained from peripheral blood lymphocytes of 21 patients with diagnosed atherosclerosis. The specific fragment of the analysed gene was obtained through amplification with the use of cDNA synthesised in the reaction of reverse transcription. The test of expression was conducted with the use of the Real-Time PCR method. In the studied cases, the level of expression of the analysed gene was compared to the level of expression of the reference gene, B2M. Results. The study showed that mRNA of the BIRC5 and BIRC6 genes is present in the cells of patients with atherosclerosis, as well as in the cells of healthy individuals. The cells taken from the patients with atherosclerosis were mainly characterized by an increased gene expression in comparison to the normal cells. Conclusion. Increased BIRC6 and BIRC5 gene expression in the cells of the patients with atherosclerosis can suggest an increased amount of the inhibitor protein BRUCE and survivin, and also decreased sensitivity of cells to apoptosis. In the case of the patients who had significantly higher expression of the BIRC6 gene in lymphocytes compared to the norm, hypertension and diabetes mellitus were more common
1. Mota M, Popa SG, Mota E, Mitrea A, Catrinoiu D, Cheta DM, Guja C, Hancu N, Ionescu-Tirgoviste C, Lichiardopol R, Mihai BM, Popa AR, Zetu C, Bala CG, Roman G, Serafinceanu C, Serban V, Timar R, Veresiu IA, Vlad AR. Prevalence of diabetesmellitus and prediabetes in the adult Romanian population: PREDATORR study. J Diabetes. 2016;8:336-44.
2. Sorrentino FS, Matteini S, Bonifazzi C, Sebastiani A, Parmeggiani F. Diabetic retinopathy and endothelin system: microangiopathy versus endothelial dysfunction. Eye. 2018; 32:1157–63.
28. Amani R, Saeidi S, Nazari Z, Nematpour S. Correlationbetween dietary zinc intakes and its serum levels with depression scales in young female students. Biol Trace Elem Res. 2010;137:150-8.
29. Siwek M, Dudek D, Zięba A, Nowak G. Stężenie cynku w surowicy jako obwodowy marker zaburzeń depresyjnych. Farmakoter Psychiatr Neurol. 2006;3:141-9.
30. Jayawardena R, Ranasinghe P, Galappatthy P, et al. Effects of zinc supplementation on diabetesmellitus: a systematic review and meta-analy-sis. Diabetol Metab Syndr. 2012;4:13.
31. Zdrojewicz Z
Patrycja Chylińska-Wrzos, Marta Lis-Sochocka and Barbara Jodłowska-Jędrych
, black seeds and honey on oral mucosal healing in rabbits (histological and immunohistochemical study on TGF-β3). Int J Sci Res. 2017;2319-7064. DOI:10.21275/ART20164558.
28. Lotfy M, Badra G, Burham W, Alenzi FQ. Combined use of honey, bee propolis and myrrh in healing a deep, infected wound in a patient with diabetesmellitus. Br J Biomed Scie. 2006;63(4):171-3.
29. Henshaw FR, Bolton T, Nube V, et al. Topical application of the bee hive protectant propolis is well tolerated and improves human diabetic foot ulcer healing in a prospective feasibility study
Lucas de Lucena de Simões, Eline Autran de Lima, Gabriela Carvalho Jurema Santos, Tafnes Oliveira, Elenilson Maximino Bernardo, Luana Olegário, Erika Rabelo Fortes Siqueira and Matheus Santos de Sousa Fernandes
) Osteoporose e outras doenças osteometabólicas no idoso. Einstein, 6(sup 1): S74-S8.
28. Yki-Järvinen H. (2015) Pathogenesis of nonalcoholic fatty liver disease (NAFLD). International Textbook of DiabetesMellitus, 2: 283. DOI: 10.1002/9781118387658.ch19.