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Diabetes mellitus type 2 in the elderly

Antypsychotics and New Onset Diabetes Mellitus: An Overview of the Literature. Pharmacopsychiatry. 2004;37(1):1-11. 5. Sinclair A. Special Considerations in Older Adults with Diabetes: Meeting the Challenge. Diabetes Spectr. 2006;19:229-33. 6. Inouye S, Studenski S, Tinetti M, Kuchel G. Geriatric Syndromes: Clinical, Research and Policy Implications of a Core Geriatric Concept. J Am Geriatr Soc. 2007;55(5):780-91. 7. Cowie C, Rust K, Byrd-Holt D, et al. Prevalence of Diabetes and Impaired Fasting Glucose in Adults in the U

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Most frequent problems of pregnant women with gestational diabetes mellitus

, Samoiluk O. Jakość życia kobiet z cukrzycą ciążową. Probl Pielęg. 2014;22(4):459-63. 5. Kopacz K, Myśliwiec M, Techmańska I, et al. Cukrzyca ciążowa - narastający problem diagnostyczny i epidemiologiczny. Diabetol Prakt. 2011;12 (3):96-102. 6. Kutowska J, Gierszewska M, Mieczkowska E, et al. Quality of life among women with gestational diabetes mellitus. Med Biol Sci. 2012;26(1):133-8. 7. Kalka D. Poczucie jakości życia a objawy depresji i sposoby radzenia sobie ze stresem u osób z cukrzycą typu 2 - doniesienia wstępne

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Abnormal Levels of Inflammatory and Oxidative Stress Markers in Patients with Arterial Hypertension and Diabetes Mellitus

Summary

Individuals with hypertension and diabetes mellitus are at high risk of cerebrovascular and cardiovascular morbidity and mortality. Recent advances in the multifactorial pathophysiology of atherogenesis provide important information about the complex interrelations between traditional risk factors, inflammation and oxidative stress in mediating all stages of atherosclerosis. The objective of the study was to determine if some inflammatory and oxidative stress markers in patients with arterial hypertension and diabetes mellitus differ from those in healthy age-matched controls. Our results revealed a significant difference in blood pro/antioxidant activities in hypertensive diabetics and the controls. The investigation of inflammatory and oxidative stress markers along with traditional risk factors proves useful in complex assessment of vascular risk and primary prophylaxis of cerebrovascular and cardiovascular events.

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Risk Factors for Coronary Artery Diseases: A Study Among Patients With Ischemic Heart Disease in India (Kerala)

Summary

Coronary artery disease (CAD) is a condition that develops due to accumulation of atherosclerotic plaque in the epicardial coronary arteries, leading to myocardial ischemia. It is the leading cause of death worldwide and is a common complex disease. A study was carried out in a group of 496 patients with acute coronary syndrome or with angiographic or stress test evidence for coronary artery disease, admitted to the Department of Cardiology at Lourdes Heart Institute and Neuro Centre during the period June-August 2012. The risk factors studied were hypertension, diabetes mellitus, dyslipidemia, body mass index, smoking and family history of CAD. The results demonstrated that in both males and females of the Indian population studies, diabetes and dyslipidemia were major risk factors for CAD, while hypertension was not a major risk factor. Therefore, early detection and treatment of diabetes mellitus and dyslipidemia play a vital role in prevention of CAD in Indian population.

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Levels Of Resistin And Visfatin In Patients With Metabolic Syndrome

.1111/j.1749-6632.2010.05875.x. 5. Dogru T, Sonmez A, Tasci I, Bozoglu E. Yilmaz MI, Gene H. at al. Plasma resistin levels in patients with newly diagnosed untreated type 2 diabetes mellitus and impaired glucose tolerance. Diabetes Res Clin Pract. 2007;76 (1):2-7. 6. Norata GD, Ongari M, Garlaschelli K, Raselli S, Grigore L, Catapano AL. Plasma resistin levels correlate with determinants of the metabolic syndrome. Eur J Endocrinol. 2007;156(2):279-84. 7. Utzschneider K, Carr D, Tong J, Wallace T, Hull R, Zrika S at al. Resistin is not associated with

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The gene expression of class III inhibitors of apoptosis in arteriosclerotic disease

Abstract

Introduction. Recent research shows that programmed cell death has great importance in the pathomechanism of atherosclerosis. The BIRC5 and BIRC6 genes belong to Class III IAPs with the anti-apoptotic effect. The proteins display multidirectional action. According to the available literature, in addition to the effect of apoptosis inhibition they also display other properties. It is suggested that they play an important role in the processes of proliferation and cellular differentiation. Aim. The aim of the study was to assess the expression of the BIRC5 and BIRC6 genes in normal peripheral blood lymphocytes and in peripheral blood lymphocytes of patients diagnosed with atherosclerosis. Material and methods. The analysis was carried out on RNA samples obtained from peripheral blood lymphocytes of 21 patients with diagnosed atherosclerosis. The specific fragment of the analysed gene was obtained through amplification with the use of cDNA synthesised in the reaction of reverse transcription. The test of expression was conducted with the use of the Real-Time PCR method. In the studied cases, the level of expression of the analysed gene was compared to the level of expression of the reference gene, B2M. Results. The study showed that mRNA of the BIRC5 and BIRC6 genes is present in the cells of patients with atherosclerosis, as well as in the cells of healthy individuals. The cells taken from the patients with atherosclerosis were mainly characterized by an increased gene expression in comparison to the normal cells. Conclusion. Increased BIRC6 and BIRC5 gene expression in the cells of the patients with atherosclerosis can suggest an increased amount of the inhibitor protein BRUCE and survivin, and also decreased sensitivity of cells to apoptosis. In the case of the patients who had significantly higher expression of the BIRC6 gene in lymphocytes compared to the norm, hypertension and diabetes mellitus were more common

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Diabetic nephropathy in type 2 diabetes – from pathological mechanisms to clinical occupational medicine practice

References 1. Mota M, Popa SG, Mota E, Mitrea A, Catrinoiu D, Cheta DM, Guja C, Hancu N, Ionescu-Tirgoviste C, Lichiardopol R, Mihai BM, Popa AR, Zetu C, Bala CG, Roman G, Serafinceanu C, Serban V, Timar R, Veresiu IA, Vlad AR. Prevalence of diabetes mellitus and prediabetes in the adult Romanian population: PREDATORR study. J Diabetes. 2016;8:336-44. 2. Sorrentino FS, Matteini S, Bonifazzi C, Sebastiani A, Parmeggiani F. Diabetic retinopathy and endothelin system: microangiopathy versus endothelial dysfunction. Eye. 2018; 32:1157–63. 3.Vinod PB

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The Biomedical Role of Zinc in the Functioning of the Human Organism

. 2010;5:15349. 28. Amani R, Saeidi S, Nazari Z, Nematpour S. Correlationbetween dietary zinc intakes and its serum levels with depression scales in young female students. Biol Trace Elem Res. 2010;137:150-8. 29. Siwek M, Dudek D, Zięba A, Nowak G. Stężenie cynku w surowicy jako obwodowy marker zaburzeń depresyjnych. Farmakoter Psychiatr Neurol. 2006;3:141-9. 30. Jayawardena R, Ranasinghe P, Galappatthy P, et al. Effects of zinc supplementation on diabetes mellitus: a systematic review and meta-analy-sis. Diabetol Metab Syndr. 2012;4:13. 31. Zdrojewicz Z

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Use of propolis in difficult to heal diabetic wounds. Short review

, black seeds and honey on oral mucosal healing in rabbits (histological and immunohistochemical study on TGF-β3). Int J Sci Res. 2017;2319-7064. DOI:10.21275/ART20164558. 28. Lotfy M, Badra G, Burham W, Alenzi FQ. Combined use of honey, bee propolis and myrrh in healing a deep, infected wound in a patient with diabetes mellitus. Br J Biomed Scie. 2006;63(4):171-3. 29. Henshaw FR, Bolton T, Nube V, et al. Topical application of the bee hive protectant propolis is well tolerated and improves human diabetic foot ulcer healing in a prospective feasibility study

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Different levels of physical activity and anthropometric profile in patients infected with hepatitis C virus

) Osteoporose e outras doenças osteometabólicas no idoso. Einstein, 6(sup 1): S74-S8. 28. Yki-Järvinen H. (2015) Pathogenesis of nonalcoholic fatty liver disease (NAFLD). International Textbook of Diabetes Mellitus, 2: 283. DOI: 10.1002/9781118387658.ch19.

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