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Maternal Lipids May Predict Fetal Growth in Type 2 Diabetes Mellitus and Gestational Diabetes Mellitus Pregnancies

REFERENCES 1. Horosz E, Bomba Opon D, Wielogos M, Szymanska M, Bartlkowink R. Effects of maternal lipids on the fetal growth in gestational diabetes. Neuro Endocrinol Lett. 2009; 30: 652–6. 2. Schaefer-Graf UM, Meitzner K, Ortega-Senovilla H, Graf K, Vetter K, Abou-Dakan M, et al. Differences in the implications of maternal lipids on fetal metabolism and growth between gestational diabetes mellitus and control pregnancies. Diabet Med. 2011; 28: 1053–9. 3. Son GH, Kwon JY, Kim YH, Park YW. Maternal serum triglycerides as predictive factors for

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Effect of Lipid Parameters on Foetal Growth In Gestational Diabetes Mellitus Pregnancies

References 1. Vahratian A, Misra VK, Trudeau S, Misra DP. Prepregnancy body mass indexand gestational age-dependent changes in lipid levels during pregnancy. Obstet Gynecol. 2010; 116: 107–113. 2. Koukkou E, Watts GF, Lowy C. Serum lipid, lipoprotein and apolipoproteinchanges in gestational diabetes mellitus: a cross-sectional and prospectivestudy. J Clin Pathol. 1996; 49: 634–637. 3. Wiznitzer A, Mayer A, Novack V, Sheiner E, Gilutz H, Malhotra A, et al. Association of lipid levels during gestation with preeclampsia and gestational diabetes mellitus: a

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Some Psychological Aspects of T1DM in Children and Adolescents

impact of life changes: Development of the life experiences survey. J Consult Clin Psychol. 1978; 46: 932-46. 24. Sipetic S, Vlajinac H, Marinkovi J, Kocev N, Milan B, Ratkov I, Sajic S. Stressful life events and psychological dysfunctions before the onset of type 1 diabetes mellitus. J Pediatr Endocrinol Metab. 2007; 20 (4): 527-34. 25. Schiffrin A. Psychosocial issues in pediatric diabetes. Curr Diab Rep. 2001 1(1): 33-40.

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Homeostasis Model Assessment - Insulin Resistance and Sensitivity (HOMA-IR and IS) Index in Overweight Children Born Small for Gestational Age (SGA)

mellitus and its complications: Report of a WHO Consultation. Part 1. Diagnosis and classification of diabetes mellitus. 2007 11. American Diabetes, Association. Diagnosis and classification of diabetes mellitus. Diabetes Care. 2005; 28(1): S37–42. 12. Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia. 1985 Jul; 28(7): 412-419. 13. Nolan JJ, Færch K. Estimating insulin sensitivity and

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The Impact of Glyco-Metabolic Status in Patients Treated for Acute Coronary Syndrome

Disorders 2017; 16: 14. 4. Tamita K, Katayama M, Takagi T, et al. Newly diagnosed glucose intolerance and prognosis after acute myocardial infarction: comparison of post-challenge versus fasting glucose concentrations. Heart 2012; 98(11): 848-54. 5. Lazzeri C, Valente S, Chiostri M, et al. Clinical significance of glycated hemoglobin in the acute phase of ST elevation myocardial infarction. World J Cardiol. 2014; 6(4): 140-7. 6. George A, Bhatia RT, Buchanan GL, et al. Impaired Glucose Tolerance or Newly Diagnosed Diabetes Mellitus Diagnosed during

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Retinal Complications in Diabetes Mellitus: Importance of Screening and Management

References 1. Bennett H, Knowler WC. Definition, Diagnosis and Classification of diabetes mellitus and glucose homeostasis. In: Khan R, Weir GC, King GL, Jacobson AM, Moses AC, Smith RJ editors. Joslin Diabetes Center. Boston: Lipincott Wiliams & Wilkins; 2005, p. 105-13. 2. Diabetes Mellitus Complications. In: Larsen. Williams Textbook of Endocrinology. 10th ed. 2003. Available from: http://members.tripod.com/~enotes/dm_complicatio ns.htm 3. Health Intelligence: Analyzing health data, generating and communicating evidence to improve population health

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Carotid Artery Disease in Diabetic Patients

References 1. Selby JV, Ray GT, Zhang D, et al. Excess costs of medical care for patients with diabetes in managed care population. Diabetes Care. 1997; 20: 1396-1402. 1b. Berry J, Keebler Me, McGuire DK. Diabetes Mellitus and Cardiovascular Disease: Pandora's Box has been opened. Herz. 2004; 29(5): 456-62. 2. Kissela BM, Khoury J, Kleindorfer D, et al. Epidemiology of Ischemic Stroke in Patients with Diabetes. The Greater Cincinnati/Northern Kentucky Stroke study. Diabetes care. 2005; 28: 355-359. 2b. Van Wijk I, Kappelle LJ, van Gijn J, Koudstaal PJ

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The Eysenck Personality Profile in Selected Groups of Ophthalmological Patients

, Carrozzino D, Patierno C, Vitacolonna E, Fulcheri M. (2017). Negative Affectivity Predicts Lower Quality of Life and Metabolic Control in Type 2 Diabetes Patients: A Structural Equation Modeling Approach. Frontiers in Psychology; 8: 831. 18. Shao Y, Yin H, Wan C. (2017) Type D personality as a predictor of self-efficacy and social support in patients with type 2 diabetes mellitus. Neuropsychiatric Disease and Treatment; 13: 855-861. 19. Olsson GM, Hulting A-L, Montgomery SM. (2008) Cognitive function in children and subsequent type 2 diabetes. Diabetes Care 31

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Hyperfibrinogenemia in Peripheral Arterial Disease: Coexistent and Independent Risk Factor (A Report of Two Cases and Review of Literature)

Abstract

These case reports aim to show that hyperfibrinogenemia is a risk factor for the progression and prognosis of peripheral arterial disease (PAD), in patients with and without diabetes mellitus type 2.

We present a patient with PAD who has type 2 diabetes mellitus, who has previously been repeatedly treated for lower limb ischemia with multiple vascular surgeries performed. A few weeks before admission the patient developed critical lower limb ischemia, which was treated with an iliaco-popliteal and femorofemoral bypass. The patient had elevated serum fibrinogen values. In the current admission, renewed left limb ischemia was diagnosed, and surgically evaluated with a recommendation for amputation of the left limb as a surgical recommendation. Our second patient had a stable intermittent claudication, dyslipidemia and hyperfibrinogenemia. He was successfully treated for those risk factors. Regular monitoring of the patient showed improved claudication distance and quality of life

Our case reports, supported by a literature review, demonstrate that hyperfibrinogenemia is a possible risk factor for progression and the prognosis of PAD.

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Renal Replacement Therapy in Patients with Heart and Kidney Failure

Abstract

The incidence of chronic kidney disease (CKD) in patients with chronic heart failure (CHF) is high as CKD and CHF share underlying risk factors such as arterial hypertension, diabetes mellitus and atherosclerosis. Cardiac failure leads to renal hypoperfusion and dysfunction and then fluid overload and need for aggressive diuretic therapy. However, development of diuretic resistance represents a significant problem in the management of these patients.

The role of Renal Replacement Therapy (RRT) is important for patients who do not response to conservative management of fluid overload facilitating the failing heart to restore function. According to the guidelines, venovenous isolated Ultrafiltration (UF) is indicated for patients with refractory congestion not responding to medical therapy with loop diuretics and infusion of dopamine. A systematic review of randomized controlled trials on the effect of UF vs. IV furosemide for decompensated heart failure showed a benefit of UF on total body weight loss and on readmissions due to heart failure in patients with decompensated heart failure and CKD. Peritoneal dialysis (PD) can provide efficient ultrafiltration and sodium extraction in volume overloaded patients followed by decline of hospitalization days, decrease of body weight and improvement of LVEF in patients with refractory heart failure. The continuous draw of ultrafiltrate is followed by a lesser risk of abrupt hypotension and better preservation of the residual kidney function. This represents a significant advantage of PD over intermittent UF by dialysis.

In conclusion, application of UF by dialysis and PD is followed by significant total body weight loss, reduced need for hospital readmissions and better quality of life. PD has a higher probability of preservation of residual kidney function and can be used by patients at home.

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