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Factors involved in the development of pituitary and hypothalamus: a short review

neurohormones regulating anterior pituitary function. Recent Prog Horm Res. 1968;24:497–588. 10. Peters A, Conrad M, Hubold C, Schweiger U, Fischer B, Fehm HL. The principle of homeostasis in the hypothalamus-pituitary-adrenal system: new insight from positive feedback. Am J Physiol Integr Comp Physiol. 2007; DOI:10.1152/ajpregu.00907.2006. 11. Markakis EA. Development of the neuroendocrine hypothalamus. Front Neuroendocrinol. 2002;23:257–91; DOI:10.1016/S0091-3022(02)00003-1. 12. Swanson LW. Brain maps 4.0-Structure of the rat brain: An open access atlas

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The Development of Business Standardization and Integrated Management Systems

References Funck D, Mayer M, Schwendt S. Integrierte Managementsysteme im Spiegel einer internationalen Expertenbefragung - Stand und Entwicklung im Handels- und Dienstleistungssektor. Göttingen University, 2001. Garvare R. Sustainable development: Extending the scope of Business Excellence Models. Measuring Business Excellence, 2001; 5 (3). Wilkinson G, Dale BG. Integrated management systems: a model based on a total quality approach. Managing Service Quality, 2001; 11 (5): 318

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Associations of cholesterol and vitamin D metabolites with the risk for development of high grade colorectal cancer

median (interquartile range). Categorical data are presented as absolute frequencies and analyzed by the Chi-square test. For comparison of continuous data with normal and asymmetrical distribution were used Student t-test and Mann-Whitney U-test, respectively. Comparison of data stratified according to tumor grades was performed by Kruskal-Wallis test. Correlation analysis was performed by using Spearman correlation coefficients. Univariate logistic regression was employed for detection of significant predictors of CRC development and tumor grade. Adjustment in

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Tadeusz Stefan Kurkiewicz (1885-1962) – His Important Contribution to Contemporary Cardiology

in Poznań. Medical Academy Printing, Poznań 2001;87-91. 8. Männer J, Pérez-Pomares JM, Macías D, Muñoz-Chápuli R. The origin, formation and developmental significance of the epicardium: A review. Cells Tissues Organs 2001;169:89–103. DOI: 10.1159/000047867 9. Cowdry EV. The mitochondrial constituents of protoplasm. In: Contributions to Embryology 1918; Vol. VIII, Nos. 24, 25, 26, Published by the Carnegie Institution of Washington, (Publication No. 271) Washington (1918). 10. Romanoff AL. The Avian Embryo. Structural and Functional Development

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Neighboring countries: The same professional aim in development laboratory medicine

-patient relationships, allowing more time for human interaction when care is boosted by digital technologies that better individualize diagnostics and patient monitoring ( 1 ). The use of digital technologies and mobile health (mHealth) applications is driven by the continuous development of connected devices, sensors and digital health applications. Digital technologies participate in precision medicine with potential impact on prevention, early diagnosis and monitoring of chronic diseases. An increasing evidence shows that mHealth technologies decreases the number of disease

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The dark side of the breastfeeding: In the light of endocrine disruptors

;190(1):32-40; DOI: 10.1016/j.toxlet.2009.06.861. 34. Fabrega F, Nadal M, Schuhmacher M, Domingo JL, Kumar V. Influence of the uncertainty in the validation of PBPK models: A case-study for PFOS and PFOA. Regul Toxicol Pharmacol. 2016;77:230-9; DOI: 10.1016/j.yrtph.2016.03.009. 35. Sharma RP, Schuhmacher M, Kumar V. The development of a pregnancy PBPK Model for Bisphenol A and its evaluation with the available biomonitoring data. Sci Total Environ. 2018;624:55-68; DOI: 10.1016/j.scitotenv.2017.12.023. 36. Teeguarden JG, Waechter JM, Jr., Clewell HJ, 3rd

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The role of uterine microbiome and epithelial-mesenchymal transition in endometrial function

Introduction Microbial colonization significantly contributes to physiological function of many organs and its alterations can be accompanied with many serious pathological conditions. At present, there is a lot of knowledge and evidence which changes the long-term concept on sterile environment in uterine cavity. Microbial colonization of endometrium was proved as well as its metabolic activity that contributes to production of substances important for pregnancy development and detoxification of xenobiotics [ 1 , 2 ]. Recent studies have analysed relation

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The genes regulating maintenance of cellular protein location are differentially expressed in porcine epithelial oviductal cells during longterm in vitro cultivation

]. Pre-implantation embryo development is affected by oviductal epithelial cells as well. Studies conducted by White et al. clearly show that the coculture of primary porcine OECs with early embryos promotes blastocyst cleavage [ 3 ]. Similar results were obtained in sheep, mouse, cattle and human, which suggests that OECs provide an optimal environment for early embryo development [ 1 ]. Since the oviduct and OECs undoubtedly play major part in early aspects of pregnancy development, from providing an optimal environment for gametes and embryos to supporting

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Analysis of expression of genes responsible for regulation of cellular proliferation and migration – microarray approach based on porcine oocyte model

Introduction The mammalian oocytes formation begins in the ovary during the fetal development. In the perinatal period the primary oocyte is surrounded by the epithelial cells which form a primordial follicle [ 1 ]. After oocytes start maturation, their nuclei–germinal vesicles (GV) break down and chromosomes condense [ 2 ]. Each oocyte in the ovary is arrested by inhibitory signals in the prophase I during the first meiotic division [ 3 ]. This arrest occurs after chromosome pairing and crossing-over process between parental chromosomes [ 4 ] The factors

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Genes regulating biochemical pathways of oxygen metabolism in porcine oviductal epithelial cells during long-term IVC

]. Free radical-induced damage caused by oxidative stress plays a significant role in the pathogenesis of many diseases [ 4 , 5 , 6 , 7 ]. Oxygen metabolism has an important role in the normal functioning of reproductive system and in the pathogenesis of infertility in females. Oxidative stress seems to be responsible for the initiation or development of reproductive organ diseases, including polycystic ovary syndrome, endometriosis, preeclampsia, etc. [ 8 , 9 , 10 ]. However, disturbances in oxygen metabolism may take place outside of pathological conditions

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