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Breast Cancer among Urban Nigerian Women: Appraising Presentation and the Quality of Care

Breast Cancer among Urban Nigerian Women: Appraising Presentation and the Quality of Care

Introduction: Late presentation is the hallmark of breast cancer among Nigerians. Awareness of the disease is low and care of this condition has not received adequate attention from Government. Health education to improve awareness was intensified in the last 2 decades. This study aims to assess the current state of care and presentation of breast cancer in Lagos, Nigeria.

Patients and Methods: A prospective study of 350 breast cancer patients seen over a period of four years at a General Surgical unit out-patient clinic of LASUTH was carried out. Data on patient characteristics, presentation, diagnosis and treatment were obtained and analyzed.

Results: Average duration of symptoms was 46.48 weeks. One fifth presented within 3 months while 17% presented after 1 year. Lumps were self-detected in 96% and 287 (82%) presented with advanced disease (stages III & IV). Two hundred and thirty seven patients (67%) received treatment and 175 (74%) among them had mastectomy. None had breast conservation surgery. One hundred and fourteen patients (48%) absconded and did complete treatment.

Conclusion: The trend of late presentation has not changed with current efforts to improve breast cancer awareness. Quality of care for our breast cancer patients is not satisfactory and needs improvement.

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Effects of high-energy ionizing radiation on organ systems in human medicine

Breast Conservation Therapy for early Breast cancer. In: Clinic Oncology, 2004, 16, 12-6. 7. Emami, B., Lyman, J., Brown, A., et al.: Tolerance of normal tissue to therapeutic irradiation. In: Radiation Oncology Biology Physic, 1991, (21), 109-122. 8. Malkinson, FD., Keane, JT.: Radiobiology of the skin: review of some effects on epidermis and hair. In: Invest Dermatology, 2001, 77(1), 133-8. 9. Weissberg, MT., Dahmke, L., Schem, C., et al.: In vitro effects of imatinib mesylate on radiosenzitivity and chemosenzitivity

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Antidiabetic Activities of Foeniculum Vulgare Mill. Essential Oil in Streptozotocin-Induced Diabetic Rats

References Aboelsoud N H. Herbal medicine in ancient Egypt. J Medicinal Plants Research. 2010;4(2):082-086. UNESCO. Culture and Health, Orientation texts- World Decade for Cultural Development Documents CLT/DEC. PRO-Paris: France, 1996:29. Schmincke KH. Medicinal Plants for forest conservation and healthcare. Non- Wood Forest Products 11, Food and Agriculture Organization of the United Nations. 2003. Bailey CJ and Day C. Traditional plant medicines as

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Validity of Autotaxin as a Novel Diagnostic Marker for Liver Fibrosis in Egyptian Chronic HCV Patients

;283(12):7776-89. 21. Li S, Zhang J. Lipopolysaccharide induces autotaxin expression in human monocytic THP-1 cells. Biochemical and biophysical research communications. 2009;378(2):264-8. 22. Widmann C, Gibson S, Jarpe MB, Johnson GL. Mitogenactivated protein kinase: conservation of a three-kinase module from yeast to human. Physiological reviews. 1999;79(1):143-80. 23. Reeves HL, Dack CL, Peak M, Burt AD, Day CP. Stressactivated protein kinases in the activation of rat hepatic stellate cells in culture. Journal of hepatology. 2000

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Recurrent invasive lobular carcinoma presenting as a ruptured breast implant

versus invasive ductal carcinoma of the breast. Surgery 1993; 114 : 637-42. Lamovec J, Bracko M. Metastatic pattern of infiltrating lobular carcinoma of the breast: an autopsy study. J Surg Oncol 1991; 48 : 28-33. Harris EER, Santiago RJ, Qin L, Hwang WT, Solin LJ. Similar long-term results of breast-conservation treatment for stage i and ii invasive lobular carcinoma compared with invasive ductal carcinoma of the breast. Cancer 2005; 103 : 2447-54. Singletary SE, Patel-Parekh L

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Association of Vitamin D Status with Body Mass Index in Adolescents in Ukraine


Background and aims: Vitamin D status in many health managements have been researched extensively, but its dependence with obesity still remains controversial. This article is devoted to examination of blood cholecalciferol levels in Ukrainian population with establishment the association of cholecalciferol levels and body mass index (BMI). Materials and methods: For this observed investigation, data were collected during the summer 2017, over a period of one week from three township areas in Carpathian region, Ukraine from 304 adults aged 19-78 years. Measured variables contained 25(OH)D level, weight and weight applied to check BMI degree. The average level of vitamin D among adolescents presented 23.1 ± 8.2 ng/ml. Female gender was associated with lower vitamin D concentrations (22.9 ± 9.3 ng/ml vs. 26.2 ± 8.5 ng/ml for men). Among the participants, 74.4% had a BMNI of 25 kg/m2 and over, and in 27.3% of them the number was 30 kg/m2 and over. Results: Violation of vitamin D status was detected in 90.5% persons. 1.8% people had been identified as severe 25(OH)D deficiency. Measurement of cholecalciferol demonstrated meaningful connection between its level and BMI only in persons with BMI 25-29.9 kg/m2. Average vitamin D concentrations in persons with BMI over30 kg/m2 did not vary to a significant range from data in persons with normal body weight. Conclusions: Vitamin D status among the adolescents in Ukraine is far from optimum. Our results confirm reliable association between cholecalciferol level and BMI in persons with overweight. Interchange between conservation of vitamin D and BMI needs additional surveys.

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Mammographycally occult high grade ductal carcinoma in situ (DCIS) as second primary breast cancer, detected with MRI: a case report

References Wedam SB, Swain SM. Contralateral breast cancer: Where does it all begin? J Clin Oncol 2005; 23 : 4585-7. Hill-Kayser CE, Harris EE, Hwang WT, Solin LJ. Twenty-year incidence and patterns of contralateral breast cancer after breast conservation treatment with radiation. Int J Radiat Oncol Biol Phys 2006; 66 : 1313-9. Gorechlad JW, McCabe EB, Higgins JH, Likosky DS, Lewis PJ, Rosenkranz KM, et al. Screening for recurrences in patients treated with breast

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Ultrasound elastography as an objective diagnostic measurement tool for lymphoedema of the treated breast in breast cancer patients following breast conserving surgery and radiotherapy

References 1. Olivotto IA, Weir LM, Kim-Sing C, Bajdik CD, Trevisan CH, Doll CM, et al. Late cosmetic results of short fractionation for breast conservation. Radiother Oncol 1996; 41: 7-13. 2. Aryana K, Gholizadeh M, Momennezhad M, Naji M, Aliakbarian M, Forghani MN, et al. Efficacy of high-energy collimator for sentinel node lymphoscintigraphy of early breast cancer patients. Radiol Oncol 2012; 46: 75-80. 3. Kelemen G, Varga Z, Lázár G, Thurzó L, Kahán Z. Cosmetic outcome 1-5 years after breast

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Impact of Dietary, Socioeconomic, and Physical Factors on Obese and Overweight Schoolchildren Living in Sidi-Bel-Abbes (West of Algeria) and Ain Defla (Centre)

endemic, the Tasmanian devil Sarcophiluis harrisii'. Biological Conservation 131: 307-324, 2006. 34. Riddoch, CJ, Boreham, C. Physical activity, physical fitness and children's health: Current concepts. In Paediatric Exercise Science and Medicine.. N. Armstrong; W. Van Mechelen (ed). Oxford University Press, pp 243-252, 2000. 35. Clermont G, Dembélé M, Bissonnette S, Richard M. Qualité de l’enseignement et qualité de l’éducation : revue des résultats de recherche. ocument préparé pour EFA Global Monitoring Report, UNESCO pp 48, 2010. 36. Kimm SY

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Diagnostic accuracy of MRI to evaluate tumour response and residual tumour size after neoadjuvant chemotherapy in breast cancer patients

. Ann Oncol 1991; 2: 347-54. 10.1093/oxfordjournals.annonc.a057953 Mauriac L Durand M Avril A Dilhuydy JM Effects of primary chemotherapy in conservative treatment of breast cancer patients with operable tumors larger than 3 cm: Results of a randomized trial in a single centre Ann Oncol 1991 2 347 54 3 Schwartz GF, Birchansky CA, Komarnicky LT, Mansfield CM, Cantor RI, Biermann WA, et al. Induction chemotherapy followed by breast conservation for locally advanced carcinoma of the breast. Cancer 1994; 73: 362-9. 10.1002/1097-0142(19940115)73:2<362::AID

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