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Differential sensitivity of myeloid and lymphoid cell populations to apoptosis in peritoneal cavity of mice with model larval Mesocestoides vogae infection

associated with alternatively activated macrophages discretely regulate helminth infection and pathogenesis in experimental mouse models. Immunobiology, 215(9-10): 704 – 708. DOI: 10.1016/j.imbio.2010.05.011 J ames , E.R., G reen , D.R. (2004): Manipulation of apoptosis in the host-parasite interaction. Trends Parasitol ., 20(6): 280 – 287. DOI: 10.1016/j.pt.2004.04.004 J enkins P., D ixon , J.B., H aywood , S., R akha , N.K., C arter , S.D., (1991): Differential regulation of murine Mesocestoides corti infection by bacterial lipopolysaccharide and

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A Global Microarray Expression Profile of Grapevine miRNAs Isolated from Cell Suspensions Pre-Treated with Apoptosis Activators

A Global Microarray Expression Profile of Grapevine miRNAs Isolated from Cell Suspensions Pre-Treated with Apoptosis Activators

In an attempt to identify novel and apoptosis/pathogen-regulated microRNAs (miRNAs) and small interfering RNAs, we performed a robust microarray screening of small RNA population from Vitis vinifera L. cv. Limberger cell suspension exposed to apoptosis activators (e.g. methyl jasmonate) or elicitors (botrycin and cinerein) derived from necrotrophic fungus Botrytis cinerea Pers. et Fries. Using a microarray expression profiling approach, we identified 22 miRNAs. We found that a majority of these miRNAs were predicted to target stress/defense-related genes of plants. Of the 22 V. vinifera miRNAs, 11 have sequence conservation in Arabidopsis thaliana but exhibited species-specific developmental and/or stress/defense-related expression patterns. Ten of the miRNAs are highly conserved in other plant species, suggesting that even conserved miRNAs may have different regulatory roles in various species. Our results show that these grapevine miRNAs can be also induced by various apoptosis inducers. Fifty-one potential targets were predicted to the newly identified miRNAs based on sequence complementarity. In addition to miRNAs, we identified 102 other novel endogenous small RNAs in Vitis, indicating that a large number of miRNAs and other small regulatory RNAs are encoded by the Vitis vinifera genome.

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Post-Transcriptional Gene Silencing Conferred by the Ectopic Expression of the Grapevine miRNA-g1 and Inhibition of the Response by Anti-miRNA-g1 Inhibitor

apoptosis is required for N-linked glycosylation. In Genes Cells , vol. 2 , 1997, no. 2, pp. 129-141, DOI: 10.1046/j.1365-2443.1997.1070303.x MALLORY, A. C. - VAUCHERET, H. 2006. Functions of microRNAs and related small RNAs in plants. In Nature Genetics , vol. 38 , 2006, no. 7, pp. 31-36. NAKASHIMA, T. - SEKIGUCHI, T. - KURAOKA, A. - FUKUSHIMA, K. - SHIBATA, Y. - KOMIYAMA, S. 1993. Molecular cloning of a human cDNA encoding a novel protein, DAD1, whose defect causes apoptotic cell death in hamster BHK21 cells. In

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Flow cytometry as a valuable tool to study cyanobacteria:A mini-review

cytometry sorting of freshwater phytoplankton, J. Appl. Phycol. 22(1): 87–100. Costa M., Costa-Rodrigues J., Fernandes M.H., Barros P., Vasconcelos V., Martins R., 2012, Marine cyanobacteria compounds with anticancer properties: a review on the implication of apoptosis, Mar. Drugs 10(10): 2181–2207. Davis D., 2007, Cell sorting by flow cytometry, [in:] Macey M.G. (ed.), Flow cytometry: principles and applications, Humana Press, New York: 257–276. Dennis M.A., Landman M., Wood S.A., Hamilton D., 2011, Application of flow cytometry for examining

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Garlic Sulfur Compounds Suppress Cancerogenesis and Oxidative Stress: a Review

the proliferation and induces apoptosis of human colon cancer cells through oxidative modification of beta-tubulin. Journal of Biological Chemistry, 280, 41487-41493. doi: 10.1074/jbc. M507127200. Iciek M, Kwiecien I, Wlodek L (2009): Biological properties of garlic and garlic-derived organosulfur compounds. Environmental and Molecular Mutagenesis, 50, 247-265. doi: 10.1002/em.20474. Ide N, Lau BHS (2001): Garlic compounds minimize intracel - lular oxidative stress and inhibit nuclear factor-kappa B activation. Journal of Nutrition

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Researches on Morphofunctional Status of the Digestive Tract of Red Deer (Cervus elaphus L.) Bred in Latvia

References Allen, J. M., Hughes, J., & Bloom, S. R. (1987). Presence, distribution, and pharmacological effects of neuropeptide Y in mammalian gastrointestinal tract. Digestive Diseases and Sciences , 32(5), 506-512. Arhipova, I., & Bāliņa, S. (2006). Statistika ekonomikā. Risinājumi ar SPSS un Microsoft Excel (2. izd.). Rīga: Datorzinību centrs. Brunner, T., & Mueller, C. (2003). Apoptosis in disease: about shortage and excess. Essays Biochem. , 39, 119

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Nutritional Effects on Boar Taint in Entire Male Pigs: A Review

Abstract

Boar taint is one of topical problems in fattening pigs. It is caused by two main compounds — androstenone and skatole. Androstenone is a steroid feromone, which is synthesized and metabolized in liver and testes. Skatole is produced by intestinal bacteria by metabolization of trypthophan. Both these substances are metabolized by cytochrome P450 and the unmetabolized residues accumulate in adipose tissue. This review describes the possible nutritional effects on boar taint reduction. Skatole is the main component, which could be reduced by nutrition in entire male pigs. The presence in adipose tissue can be reduced by apoptosis of intestinal cells by raw potato starch. Another method is to influence the microbial population in the gastrointestinal tract by organic acids or fructooligosaccharides. Recently, attention has been directed towards the enzymatic system in the liver. There are a few possibilities of reducing skatole as well as androstenone by influencing the liver enzymatic system. They may be particularly affected by secondary plant metabolites and flavonoids. However, more research is required in this area to clarify physiological regularities and all the relationships in the metabolism detoxification from xenobiotic substances.

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Organo-Sulphur Garlic Compounds Influence Viability of Mammalian Cells: A Review

apoptosis and histone hyperacetylation by diallyl disulfide in prostate cancer cell line PC-3. Cancer Letters, 251, 59–67. doi: 10.1016/j.canlet.2006.11.001. Banerjee SK, Maulik M, Manchanda SC, Dinda AK, Das TK, Maulik SK (2001): Garlic-induced alteration in rat liver and kidney morphology and associated changes in endogenous antioxidant status. Food and Chemical Toxicology, 39, 793–797. doi: 10.1016/S0278-6915(01)00018-7. Banerjee SK, Mukherjee PK, Maulik SK (2003): Garlic as an antioxidant: the good, the bad and the ugly. Phytotherapy Research, 17, 97

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Effect of Microencapsulation by Spray-Drying and Freeze-Drying Technique on the Antioxidant Properties of Blueberry (Vaccinium myrtillus) Juice Polyphenolic Compounds

., Microencapsulation by spray drying of bioactive compounds from cactus pear (Opunia ficus-indica). Food Chem., 2009, 114, 616–622. 22. Seeram N.P., Adams L.S., Zhang Y., Lee R., Sand D., Scheuller H.S., Heber D., Blackberry, black raspberry, blueberry, cranberry, red raspberry, and strawberry extracts inhibit growth and stimulate apoptosis of human cancer cells in vitro . J. Agric. Food Chem., 2006, 54, 9329–9339. 23. Srivastava A., Akoh C.C., Fischer J., Krewer G., Effect of anthocyanin fractions from selected cultivars of Georgia-grown blueberries on apoptosis and

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Influence of Polyphenol Extract from Evening Primrose (Oenothera Paradoxa) Seeds on Proliferation of Caco-2 Cells and on Expression, Synthesis and Activity of Matrix Metalloproteinases and Their Inhibitors

from evening primrose (Oenothera paradoxa) defatted seeds induce apoptosis in human colon cancer Caco-2 cells. J. Agric. Food Chem., 2011, 59, 6985-6997. 15. Hadler-Olsen E., Winberg J.O., Uhlin-Hansen L., Matrix metalloproteinases in cancer: their value as diagnostic and prognostic markers and therapeutic targets. Tumor Biol., 2013, 34, 2041-2051. 16. Hartzfeld P.W., Forkner R., Hunter M.D., Hagerman A.E., Determination of hydrolyzable tannins (gallotannins and ellagitannins) after reaction with potassium iodate. J. Agric. Food Chem

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