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Comparative Study of the Effect of Various Forms of Quercetin on Experimental Diabetes

. Inhibitors of Poly(ADP-Ribose)Polymerase-1 as Agents Providing Correction of Brain Dysfunctions Induced by Experimental Diabetes. Neurophysiology 49(3): 183-193, 2017. 7. Korda MM. Status of the antioxidant, monooxygenase and humoral immune system of the body in d-galactosamine hepatitis. Ukrain'skyi Biokhimichnyi Zhurnal 68(1): 72-75, 1996. 8. Posokhova KA, Zozuliak NB, Cherniashova VV, Stechyshyn IP. Method of experimental obesity modeling. Patent of Ukraine 92289: 15, 2014. 9. Moyer VA. Screening for and management of

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Antioxidant Effect of Purple Eggplant Flour (Solanum melongena L.) Against Oxidative Stress in Hyperglycaemic Rats

type 2 diabetic rats. Phytomedicine 22: 952-960, 2015. 8. Evans JL, Goldfine ID, Maddux BA, Grodsky GM . Are oxidative stress-activated signaling pathways mediators of insulin resistance and beta-cell dysfunction? Diabetes 52: 1–8, 2003. 9. Johansen JS, Harris AK, Rychly DJ, Ergul A . Oxidative stress and the use of antioxidants in diabetes: linking basic science to clinical practice. Cardiovascular Diabetology 4: 5, 2005. 10. Robertson RP . Oxidative stress and impaired insulin secretion in type 2 diabetes. Curr Opin Pharmacol 6: 615

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Potency of Cape Gooseberry (Physalis Peruviana) Juice in Improving Antioxidant and Adiponectin Level of High Fat Diet Streptozotocin Rat Model

383(9922): 1068–1083, 2014. 4. Styskal J, Van Remmen H, Richardson A, Salmon AB . Oxidative stress and diabetes: What can we learn about insulin resistance from antioxidant mutant mouse models?. Free Radic. Biol. Med 52(1): 46–58, 2012. 5. Asghar A, Sheikh N . Role of immune cells in obesity induced low grade inflammation and insulin resistance. Cell Immunol 315: 18–26, 2017. 6. Caselli C . Role of adiponectin system in insulin resistance. Mol Genet Metab 113; 155–160, 2014. 7. G. R. Hajer, T. W. Van Haeften, and F. L. J. Visseren

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Micronutrients and Oral Health an Opportunity to Prevent Oral Diseases

Geriatric Population in India (P01-005-19). Curr Dev Nutr 3(Supp 1), 2019. 23. Wu YC, Wang YP, Chang JYF, Cheng SJ, Chen HM, Sun A . Oral manifestations and blood profile in patients with iron deficiency anemia. J Formos Med Assoc 113(2): 83–87,2014. 24. Evans SL, Tolbert C, Arceneaux JEL, Byers BR . Enhanced toxicity of copper for streptococcus mutans under anaerobic condition. Antimicrob Agents Chemother 29(2): 342-43, 1986. 25. Rahman K. Studies on free radicals, antioxidants, and co-factors. Clin Intev Aging 2(2): 219-236, 2007 26. Bo S

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Quinoa Beverages: Formulation, Processing and Potential Health Benefits

–1267, 2015. Accessed at: http://www.sciencedirect.com/science/article/pii/S0023643815002479 6. Owusu-Mensah E, Oduro I, Sarfo KJ. Steeping: a way of improving the malting of rice grain. J Food Biochem 35: 80–91, 2011. 7. Carciochi RA, Manrique GD, Dimitrov K. Changes in phenolic composition and antioxidant activity during germination of quinoa seeds (Chenopodium quinoa Willd.). Int Food Res J 21: 767–773, 2014. Accessed at : http://www.ifrj.upm.edu.my/21%20(02)%202014/47%20IFRJ%2021%20(02)%202014%20Carchiochi%20527.pdf 8. Gokavi SS, Malleshi NG

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Interrelations Between Inflammatory and Oxidative Stress Biomarkers in Obese Women with Two Complications (Hypertension, Diabetes)

R eferences 1. Nakamura K, Fuster JJ, Walsh K . Adipokines: A link between obesity and cardiovascular disease. J Cardiol 63(4): 250-9, 2014. 2. Gariballa S, Afandi B, Abuhaltem M, Yassin J, Habib H, Ibrahim W . Oxidative damage and inflammation in obese diabetic Emirati subjects supplemented with antioxidants and B-vitamins: a randomized placebo-controlled trail. Nutr Metab (Lond) 10(1): 21, 2013. 3. Mitu F, Rezuş E, Banu C, Jufă C, Mitu O, Dima-Cozma C . Inflammatory markers in hypertensive patients and influence of some associated

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Beneficial Effects of Coenzyme Q10 in Reduction of Testicular Tissue Alteration Following Induction of Diabetes in Adult Rats

diabetic rats. Anat Rec 195: 415-430, 1979. 4. Kianifard D, Sadrkhanlou RA, Hasanzadeh S. The Ultrastructural Changes of the Sertoli and Leydig Cells Following Streptozotocin Induced Diabetes. Iran J Bas Med Sci 15: 623-35, 2011. 5. Giacco F, Brownlee M. Oxidative stress and diabetic complications. Circ Res 107: 1058-1070, 2010. 6. Maritim AC, Sanders RA, Watkins JB. Diabetes, oxidative stress, and antioxidants: a review. J Biochem Mol Toxicol 17: 24-38, 2003. 7. Grootegoed JA, Oonk RB, Jansen R, Van der

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Oral Supplementation Effect of Iron and its Complex Form With Quercetin on Oxidant Status and on Redistribution of Essential Metals in Organs of Streptozotocin Diabetic Rats

References 1. Cho N, Shaw J, Karuranga S et al . IDF Diabetes Atlas: global estimates of diabetes prevalence for 2017 and projections for 2045. Diabetes Res Clin Pract 138: 271-281, 2018. 2. Roghani M, Baluchnejadmojarad T . Hypoglycemic and hypolipidemic effect and antioxidant activity of chronic epigallocatechin-gallate in streptozotocin-diabetic rats. Pathophysiology 17: 55-59, 2010. 3. Presley TD, A’ja VD, Jeffers AB et al . The variation of macro-and micro-minerals of tissues in diabetic and non-diabetic rats. J Trace Elem Med Biol 39

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Study of the Protective Effects of Quince (Cydonia Oblonga) Leaf Extract on Fertility Alterations and Gonadal Dysfunction Induced by Monosodium Glutamate in Adult Male Wistar Rats

: 393-399, 2008. 24. Silva BM, Andrade PB, Valentao P, Ferreres F, Seabra RM, Ferreira MA. Quince (Cydonia oblonga Miller) fruit (pulp, peel, and seed) and Jam: antioxidant activity. J Agric Food Chem 52: 4705-4712, 2004. 25. Pizzi WJ, Barnhart JE, Fanslow DJ. Monosodium glutamate administration to the newborn reduces reproductive ability in female and male mice. Science 196 (4288): 452-454, 1977. 26. Das RS, Ghosh SK. Long-term effects of monosodium glutamate on spermatogenesis following neonatal exposure in albino mice

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Endothelial Dysfunction in Diabetes – Clasic Sources of Vascular Oxidative Stress (Nadph Oxidases, Enos Uncoupling and Xanthine Oxidase)

Abstract

Cardiovascular disease is the leading cause of disease / mortality worldwide. It is generally accepted that increased production of reactive oxygen species (ROS) has an important role in cardiovascular pathology, contributing to endothelial dysfunction and to the aggravation of atherosclerosis. Among all cardiovascular risk factors, diabetes mellitus is one of the most important. The worldwide prevalence of diabetes has increased rapidly even in developing countries, doubling the combined risk of cardiovascular events in patients with hypertension. In diabetes, increased reactive oxygen species (ROS) production leads to endothelial dysfunction, recognized by the presence of impaired vascular relaxation, increased vascular smooth muscle cells growth and hypertrophy, all together contributing to atherosclerotic plaque formation. On this basis, the vascular endothelium has emerged as a therapeutic target, with the aim to improve systemic metabolic state by improving vascular function. In this review we have focused on the most important sources of reactive oxygen species generated by vascular endothelium in diabetic patients (NADPH Oxidases, eNOS uncoupling, Xanthine oxidase). The importance of oxidative stress in mediating the vascular complications of diabetes is supported by studies showing that antioxidant therapy correct the vascular function in humans or in experimental models of diabetes. Therefore, understanding the physiological mechanisms involved in vascular disorders resulting from hyperglycemia is essential for the proper use of available therapeutic resources.

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