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Problems of high-dose methotrexatein oncological patients

, Tsalic M, Haim N. Actual body weight for determining doses of chemotherapy in obese cancer patients. Med Oncol 2003; 20: 363-367. Jaehde U, Kloft C. Dosis-Individualisierung in der Krebs-Chemotherapie. Pharm Unserer Zeit 2006; 2: 150-156. Skaerby T, Joensson P, Hjorth L, Behrentz M, Bjoerk O, Forestier E et al. High-dose methotrexate: on the relationship of methotrexate elimination time vs renal function and serum methotrexate levels in 1164 courses in 264 Swedish children with acute lymphoblastic leukaemia (ALL

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