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Adult B Lymphoblastic Leukemia with a Novel De Novo Chromosomal Translocation [Der(9)t(9;12)(p24;q12),-12]: A Case Report

review of literature. J Hematol Oncol. 2009; 2(1): 26-31. 3. Atlas of Genetics and Cytogenetics in Oncology and Haematology online, 1998 (http://atlasgeneticsoncol 4. Bargetzi MJ, Mühlematter D, Tichelli A, Jotterand M, Wernli M. Dicentric translocation (9;12) presenting as refractory Philadelphia chromosomepositive acute B-cell lymphoblastic leukemia. Cancer Genet Cytogenet. 1999; 113(1): 90-92. 5. D’Angelo G, Hotz AM, Todeschin P. Acute lymphoblastic leukemia with hypereosinophilia and 9p21 deletion: case

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Multidrug resistance gene 1 polymorphisms in pediatric patients with leukemia at a national referral hospital in Indonesia

[ 2 ]. The most common malignancy in the pediatric population worldwide is acute lymphoblastic leukemia (ALL). ALL is a heterogeneous group of leukemias that result from the clonal proliferation of cancerous lymphoblasts in bone marrow, and in secondary lymphoid organs. Children 1–10 years old are at particular risk of developing ALL. The overall cure rate is approximately 80% [ 3 ]. The Indonesian Paediatric Oncology Foundation stated that 2%-3% cancer cases in Indonesia occur in children [ 4 ]. Based on Cipto Mangunkusumo Hospital data from 2000-2006, there were

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Polymorphism of Biotransformation Genes and Risk of Relapse in Childhood Acute Leukemia

References Wood ME, Philips GK. Hematology/Oncology Secrets. 3rd ed. Philadelphia: Hanley & Belfus Inc., 2003. Chan KW. Acute lymphoblastic leukemia. Curr Probl Pediatr Adolesc Health Care 2002; 32(2): 40-49. Ansari M, Krajinovic M. Pharmacogenomics of acute leukemia. Pharmacogenomics 2007; 8(7): 817-834. Seeger K, Adams HP, Buchwald D, Beyermann B, Kremens B, Niemeyer C, Ritter J, Schwabe D, Harms D, Schrappe M, Henze G. TEL-AML1 fusion transcript in

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T-lymphoblastic leukemia/lymphoma in macedonian patients with Nijmegen breakage syndrome

the toes. He was admitted to the Hematology Department at the age of 9.5 with fever, disseminated lymphadenopaty, hepatosplenomegaly and leucocytosis of 27,000 × 10 9 /L. The evaluation of the peripheral blood smear showed the presence of 32.0% blast cells. The diagnosis of T-cell acute lymphoblastic leukemia (T-ALL) was established based on a standard immunohystological panel analysis. It was quite clear that the malignant disease in both children in this family was partly due to the clinical presentation of NBS. The patient was treated with the International

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Acute pre-B lymphoblastic leukemia and congenital anomalies in a child with a de novo 22q11.1q11.22 duplication

2 Chang VY, Quintero-Rivera F, Baldwin EE, Woo K, Martinez-Agosto JA, Fu C, et al . B-acute lymphoblastic leukemia and cystinuria in a patient with duplication 22q11. 21 detected by chromosomal microarray analysis. Pediatr Blood Cancer. 2011; 56(3): 470-473. Chang VY Quintero-Rivera F Baldwin EE Woo K Martinez-Agosto JA Fu C B-acute lymphoblastic leukemia and cystinuria in a patient with duplication 22q11 21 detected by chromosomal microarray analysis. Pediatr Blood Cancer 2011 56 3 470 – 473 3 ISCN 2016. An International System for

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Amplification of c-MYC and MLL Genes as a Marker of Clonal Cell Progression in Patients with Myeloid Malignancy and Trisomy of Chromosomes 8 or 11

Sci USA. 2001; 98(14): 7952-7957. Strout MP, Lorsbach RB, Shearer P, Sandlund JT, Raimondi SC. Double minute chromosomes and c-MYC amplification in a child with secondary myelodysplastic syndrome after treatment for acute lymphoblastic leukemia. Leukemia. 2000; 14(7): 1314-1315. Jennings BA, Mills KI. C-MYC locus amplification and the acquisition of trisomy 8 in the evolution of chronic myeloid leukaemia. Leuk Res. 1998; 22(10): 899-903. Slovak ML, Ho JP, Pettenati MJ, Khan A, Douer D, Lal

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Distribution of the Most Common Genetic Variants Associated with a Variable Drug Response in the Population of the Republic of Macedonia

. Methylenetetrahydrofolate reductase polymorphisms and risk of acute lymphoblastic leukemia-evidence from an updated meta-analysis including 35 studies. BMC Med Genet. 2012; 4: 13-77. 33. Acuña M, Eaton L, Cifuentes L, Massardo D. Genetic variants in the enhancer region of the thymidylate synthase gene in the Chilean population. Br J Clin Pharmacol. 2006; 61(6): 778-782. 34. Alzahrani AM, Ragia G, Hanieh H, Manolopoulos VG. Genotyping of CYP2C9 and VKORC1 in the Arabic Population of Al-Ahsa, Saudi Arabia. Biomed Res Int. 2013; 2013: 315980. doi: 10

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Altered canonical hedgehog-gli signalling axis in pesticide-induced bone marrow aplasia mouse model

and immunosuppression: the risks to public health. Health Policy Plan 1997;12:97-106. 14. Kevin Y, Urayama JK, Wiencke B, Chokkalingam AP, Metayer C, Wiemels JL. MDR1 Gene variants, indoor insecticide exposure, and the risk of childhood acute lymphoblastic leukemia. Cancer Epidemiol Biomarkers Prev 2007;16:1172-7. 15. Ledirac N, Antherieu S, Uby AD, Caron JC, Rahmani R. Effects of organochlorine insecticides on MAP kinase pathways in human HaCaT keratinocytes: key role of reactive oxygen species. Toxicol Sci 2005

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Association Between Glutathione S-Transferase Omega 1 A140D Polymorphism in the Turkish Population and Susceptibility to Non-Small Cell Lung Cancer

, Tjonneland A. Polymorphisms of glutathione S-transferase A1 and O1 and breast cancer among postmenopausal Danish women. Eur J Cancer Prev 2008;17:225-9. doi: 10.1097/ CEJ.0b013e3282b6fe1e 24. Pongstaporn W, Pakakasama S, Sanguansin S, Hongeng S, Petmitr S. Polymorphism of glutathione S-transferase Omega gene: association with risk of childhood acute lymphoblastic leukemia. J Cancer Res Clin Oncol 2009;135:673-8. doi: 10.1007/s00432-008-0501-4 25. Wang YH, Yeh SD, Shen KH, Shen CH, Juang GD, Hsu LI, Chiou HY, Chen CJ. A significantly joint

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Frequencies of Single-Nucleotide Polymorphisms and Haplotypes of the SLCO1B1 Gene in Selected Populations of the Western Balkans

References 1. Liu J, Long J, Zhang S, Fang X, Luo Y. Polymorphic variants of SLCO1B1 in neonatal hyperbilirubinemia in China. Ital J Pediatr. 2013; 39(49): 1-5. 2. Lopez-Lopez E, Martin-Guerrero I, Ballesteros J, Piсan MA, Garcia-Miguel P, Navajas A, et al. Polymor- phisms of the SLCO1B1 gene predict methotrexate-related toxicity in childhood acute lymphoblastic leukemia. Pediatr Blood Cancer. 2011; 57(4): 612-619. 3. Niemi M, Kivistц KT, Hofmann U, Schwab M, Eichelbaum M, Fromm MF. Fexofenadine pharmacokin

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