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The relation of anthropometric measurements and insulin resistance in patients with polycystic kidney disease

. [ 4 , 5 ] Obesity is a risk factor for IR; however, quantity and distribution of body fat are important determinants of obesity-related risk factors. [ 6 ] Abdominal or visceral fat is associated with higher incidence of IR and cardiovascular (CV) problems. [ 7 ] Anthropometry is a term used to define the measurements of specific body segments or regions. Anthropometric measurements including height, weight, body mass index (BMI), and body fat distribution provide valuable data regarding the future risk of diabetes and CVDs. [ 8 ] We aimed to examine the

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Application of wearable technology in clinical walking and dual task testing

clinical guidelines, [ 4 ] through wireless headphones, which contain verbal encouragement, specific walking speed ( e.g ., comfortable or fast), and reminders of completed walking time. [ 4 ] Step parameters obtained via GaitReminder App have an average of < 10% difference when tested against direct video measurements, and a similar error rate was also found when the App was used for treadmill walking or overground ambulation where the actual speed can be obtained from direct machine reading or physical measurement of time and walked distance (markings on the floor

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Elevated lactic acid during ketoacidosis: pathophysiology and management

, glycogenic hepatopathy and persistent hyperlactatemia, a diagnosis of Mauriac syndrome was made. The patient left the hospital with a basal prandial insulin schema. Her ratio lactate/pyruvate was above 30. Three months later, lactate was 4.81 mmol/L. Figure 1 Serial measurements of lactate and glycemia over 3 days of dextrose and insulin therapy Discussion Mauriac, in 1930, [ 4 ] described a syndrome in a young diabetic type 1 patient with poor glycemic control. It is characterized by excessive glycogen storage called glycogen hepatopathy associated with

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Effect of weight reduction on histological activity and fibrosis of lean nonalcoholic steatohepatitis patient

was done to assess the effect of important factors on the final outcome. Operational definition BMI : BMI was calculated as weight (kg) divided by height (m) squared; a BMI < 25 kg/m 2 was considered as lean subjects and BMI ≥ 25 kg/m 2 was used to identify non-lean subjects. Waist circumference : It was measured in the horizontal plane midway between lowest rib and the iliac crest. The measurement tried to keep the nearest 0.1 cm at the end of a normal expiration. Before recording the measurement, it was ensured that the tape was snug but did not

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Correlation of Residual Diuresis with MIS Score and Nutritional Status in Peritoneal Dialysis Patients: A Croatian Nationwide Study

-inflammation complex syndrome in patients with continuous ambulatory peritoneal dialysis. Int Urol Nephrol 2011; 43: 875-882. 43. Van Olden RW, Krediet RT, Struijk DG, et al . Measurement of residual diuresis in patients treated with continuous ambulatory peritoneal dialysis. J Am Soc Nephrol 1996; 7: 745-750. 44. Nolph KD, Moore HL & Twardowski ZJ, et al . Cross-sectional assessment of weekly urea and creatinine clearances in patients on continuous ambulatory peritoneal dialysis. ASAIO J 1992; 38: M139-M142. 45. Yang Q, Li R, Zhong Z, et al . Is cystatin

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Impact of Interdialytic Weight Gain (IDWG) on Nutritional Parameters, Cardiovascular Risk Factors and Quality of Life in Hemodialysis Patients

, Tonbul ZH. Malnutrition-Inflammation-Atherosclerosis (MIA Syndrome) in ESRD Patients. Turk Neph Dial Transpl 2005; 14: 160-165. 11. Kalantar-Zadeh K, Block G, Humphreys MH, Kopple JD. Reverse epidemiology of cardiovascular risk factors in maintenance dialysis patients. Kidney Int 2003; 63: 793-808. 12. Schiffrin EL, Lipman ML, Mann JF. Chronic kidney disease: effects on the cardiovascular system. Circulation 2007; 116: 85-97. 13. Heymsfield SB, McManus C, Smith J, et al. Anthropometric measurement of muscle mass: revised

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Left main stenting induced flow disturbances on ascending aorta and aortic arch

before the emergence of right anonymous trunk, was 28.8 ± 7.9 mm and 28.2 ± 6.7 mm, respectively. Following these measurements, the diameters of LCA and LCX were modelled as following: LM 4.5 mm, LAD 3.5 mm and LCX 2.75 mm, with bifurcation angle set up at 55°. A 12 mm length plaque inducing a stenosis of 90% was placed at the mid-shaft position ( Figure 1 ). The height of the aortic take off (distance between the origin of the LM and the aortic valve plane) was set at 10 mm, while the diameter of ascending aorta just above the left coronary origin was set at 28 mm

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Effect of MTHFR A1298C and MTRR A66G genetic mutations on homocysteine levels in the Chinese population: a systematic review and meta-analysis

.[ 20 ] Table 1 Characteristics of studies included in the meta-analyses on the association between MTHFR A1298C genotypes and homocysteine levels Study Year Design Sex (female) Age Sample size Method of plasma measurement Hcy MTHFR analysis Concomitant disease Hou et al . [ 12 ] 2016 Case–control 195 (100%) 30.6 (5.3) 195 Enzymatic cycle method FQ-PCR Healthy controls Ji et al . [ 24 ] 2004 Case–control 55 (31.4%) 67.5 177 FPIA PCR-RFLP CHD/healthy controls Kasiman et al . [ 22

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Correlation of B-type Natriuretic Peptide (BNP) with Left Ventricle Systolic Function Echocardiographic Parameters in Patients with Chronic Kidney Disease (CKD)

Abstract

Introduction. BNP plasma levels are significantly increased in heart failure and have an excellent negative predictive value for left ventricular dysfunction. Measurement of BNP level is useful for “screening” in high-risk populations. It is suitable for detection of left ventricular hypertrophy (LVH) and/or dysfunction and risk assessment in the sub-acute phase of acute myocardial infarction in hypertensive patients. The aim of our study was to find whether BNP may correlate with the left ventricular systolic function, i.e. its echocardiographic parameters in chronic kidney disease (CKD) patients.

Methods. In a prospective study performed at the Department of Nephrology and Clinic for hemodialysis at the Clinical Center in Sarajevo we followed-up 80 patients stratified in three separate groups according to CKD stage (Stage III, IV and V) for two years, regardless of their cardiovascular symptoms. We analyzed levels of BNP before and after diuretic therapy or hemodialysis and echocardiographic characteristics of the left ventricle.

Results. There was a strong negative correlation between BNP values and the size of the EF before (rho=−0.692, p<0.0001) and after diuretic therapy (rho=−0.683, p<0.0001) for patients in CKD stage III, stage IV (rho=−0.314, p>0.05) and after diuretic therapy (rho=−495, p<0.05) Similarly, a negative correlation was found for BNP and EF values before (rho=−0.432, p<0.05) and after hemodialysis (rho=−0.556, p<0.01) for stage V CKD.

Conclusions. Our study confirmed that the value of BNP in CKD patients may represent a measure of left ventricular systolic function with a strong negative correlation with ejection fraction. BNP measurement is a reliable parameter for further follow-up and prognosis in patients with established left ventricular dysfunction, acute coronary syndrome and for estimation of the left ventricular dysfunction.

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Neutrophil-Gelatinase Associated Lipocalin (N-GAL) to Assess Perioperative Acute Kidney Injury in Hand-Assisted Laparoscopic Donor Nephrectomy: A Pilot Study

Abstract

Perioperative insults, including hypotension, hypovolaemia and pneumoperitoneum may occur during laparoscopic live donor nephrectomy. These may have deleterious effects to both donor and recipient. The extent and significance of these insults is poorly understood and difficult to quantify. The aim of this study was to evaluate acute kidney injury (AKI) in the donor using the novel biomarker neutrophil-gelatinase associated lipocalin (N-GAL). We report the results of a pilot study of 20 patients undergoing hand-assisted live donor nephrectomy. eGFR and serum NGAL measurements (Triage CardioRenal Panel, Alere) were obtained preoperatively, immediately post-operatively, day 1 and 6 weeks post-operatively. Mean pre-operative eGFR was 105.6+/-10.1ml/min/1.73m2. Mean eGFR 6 weeks postoperatively demonstrated a 29.4+/-8.8% reduction from baseline. Serum N-GAL increased by 34.1+/-16.7% following an overnight fast pre-operatively (day 0) (ΔNGAL 45.1+/-36.0ng/ml), by a further 14.9+/-7.2% following surgery (immediate post-op). The largest ΔNGAL was observed during the pre-operative fasting period. ΔNGAL [day -1 to day 0] and [day -1 to post-op] were found to correlate inversely with eGFR at 6 weeks (p<0.05, r2=0.47 and p<0.001, r2=0.52 respectively). We conclude that clinically significant AKI does occur in the donor following live donor nephrectomy. Optimisation of perioperative fluid management is likely to have a protective role.

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