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Total neoadjuvant treatment of locally advanced rectal cancer with high risk factors in Slovenia

into account only the high risk group of patients in the study of Golo et al , the greater efficacy of our TNT approach is even more prominent. The difference in pCR rate is 13.8% (10.5% vs 23.3%). 15 Another difficulty in comparison with other studies presents our scheme of TNT approach which is rather unique with combination of induction ChT before CRT and consolidation ChT after it. We found only one Chinese study reporting results on TNT in LARC-HR only with similar approach: 3 cycles of induction and 3 cycles of consolidation CAPOX, but even more

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Radiology and Oncology
The Journal of Association of Radiology and Oncology
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LncRNA PVT1 promotes proliferation and invasion through enhancing Smad3 expression by sponging miR-140-5p in cervical cancer

invasion through binding miR-140-5p, which may provide new insights into the therapeutic strategy against cervical cancer. Materials and methods Cell lines and cell culture Human normal cervical epithelial cell line (End1/ E6E7) and human cervical cell lines (HeLa and SiHa) were obtained from the Cell Bank of the Chinese Academy of Sciences (Shanghai, China). The cells were maintained in Dulbecco’s minimal Eagle’s medium (DMEM; Invitrogen, Carlsbad, CA, USA) containing 6% fetal bovine serum (FBS; Gibico, Grand Island, NY, USA) and 1% penicillin/ streptomycin at

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Dusp6 inhibits epithelial-mesenchymal transition in endometrial adenocarcinoma via ERK signaling pathway

cm from the tumor site without cancer cell infiltrations) were obtained from 35 endometrial adenocarcinoma patients from 2016 to 2018 in the Department of Obstetrics and Gynecology, Shandong Provincial Hospital. The study was authorized by the Ethics Committee of Shandong University, China. Written consents were obtained from all patients. Additionally, Ishikawa 3H12 (Purchased from ATCC, USA) high-differentiated endometrial adenocarcinoma cell line was used in in vitro study. The cells were cultured in DMEM supplemented with 5% charcoal-stripped fetal bovine

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LncRNA NEAT1 promotes endometrial cancer cell proliferation, migration and invasion by regulating the miR-144-3p/EZH2 axis

-3’ (forward), and 5’- AACGCTTCACGAATTTGCGT-3’(reverse). Relative RNA levels were calculated using the 2 -ΔΔ Ct method. Cell transfection Small hairpin RNA (shRNA) for NEAT1 or its respective negative control were designed, synthesized and cloned into the shRNA vector U6/GFP/ Neo plasmid (GenePharma, Shanghai, China). A miR-144-3p mimic and its control were designed and synthesized by Sangon (Shanghai, China). The validated and purified reconstructed vectors were transfected into the indicated cells by Lipofectamine 3000 (Thermo Fisher, USA) according to the

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Transcription factors gene expression in chronic rhinosinusitis with and without nasal polyps

Ghalehbaghi B Aazami H Mohebbi A Ahmadi A Falak R Frequency of CD4+ and CD8+ T cells in Iranian chronic rhinosinusitis patients Allergy Asthma Clin Immunol 2018 14 47 10.1186/s13223-018-0270-9 21 Cao PP, Li HB, Wang BF, Wang SB, You XJ, Cui YH, et al. Distinct immunopathologic characteristics of various types of chronic rhinosinusitis in adult Chinese. J Allergy Clin Immunol 2009; 124: 478-84.e2. 10.1016/j.jaci.2009.05.017 19541359 Cao PP Li HB Wang BF Wang SB You XJ Cui YH Distinct immunopathologic

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A multi-institutional analysis of diffuse large B-cell lymphoma (DLBCL) treated with consolidative radiotherapy and the impact of cell-of-origin on outcomes

characteristics and treatment details Variable Level Number patients of (%) All patients 74 (100) Age Median (range) 61 (14–88) Males 43 (58) Gender Females 31 (42) Chinese 54 (73) Malay 10 (14) Ethnicity Indian 1 (1) Others 9 (12) Stage I–II 43 (58) III–IV 31 (42) No 44 (59) Yes 30 (41) Staging PET/CT SUV max ≤ 20 12 (40) SUV max > 20 18 (60) Involvement of extra- Nodal only 19 (26) nodal sites Extra-nodal +/- nodal 55 (74) 20 (27

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Radiological findings of porcine liver after electrochemotherapy with bleomycin

: Resona 7 and/or M9 (Mindray, Shenzhen, China) and/or Logiq S7 Pro (GE, Milwaukee, WI, USA). US examinations included B-mode to provide information about echogenicity and echotexture changes, Doppler (color and pulse-wave) to examine vessel patency and contrast enhanced ultrasound (CEUS) to evaluate the perfusion of hepatic parenchyma. The region of CEUS investigation was chosen according to the available US machine. In the case of the Mindray machine, a linear probe was used and the near-field area was preferred, whereas with the GE machine, the far-field was chosen

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