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Effect of Red Wine Consumption on Serum Oxidation and Adiponectin Levels in Overweight and Healthy Individuals

Abstract

Obesity is a well-known independent risk factor for CVD and metabolic syndrome. It has been shown that moderate red wine consumption might reduce the risk of cardiovascular disease (CVD). The aim of this study was to investigate whether red wine has anti-inflammatory and antioxidative effect in overweight subjects.

Ten overweight and 14 healthy subjects drank 200 mL/day of red wine for one month. While the Cabernet Sauvignon wine caused a significant increase in paraoxonase activity (p<0.05), it led to a decrease in basal and stimulated LDL diene levels in both of the groups (p<0.05). Total antioxidant activity increased in the two groups following wine consumption.

While wine consumption had no effect on IL-6, TNF-α and CRP levels of overweight subjects, it led to an increase in adiponectin levels.

Current data consider that regular red wine consumption may be beneficial to improve the antioxidant potential of LDL oxidation in overweight patients. In addition to the prevention of LDL oxidation, moderate wine consumption might delay the onset of atherosclerosis through an increase in paraoxonase and adiponectin levels

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Intake and Profile of Plant Polyphenols in the Diet of the Czech Population

M.J., Daily polyphenol intake in France from fruit and vegetables. J. Nutr., 2006, 136, 2368–2373. 5. Carter P., Gray L.J., Troughton J., Khunti K., Davies M.J., Fruit and vegetable intake and incidence of type 2 diabetes mellitus: systematic review and meta-analysis. Brit. Med. J., 2010, 341, 10.1136/bmj.c4229. 6. Chong M.F.F., Macdonald R., Lovegrove J.A., Fruit polyphenols and CVD risk: a review of human intervention studies. Brit. J. Nutr., 2010, 104, S28-S39. 7. Correa V.G., Tureck C., Locateli G., Peralta R.M., Koehnlein EA.A., Estimate of

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Longer Breastfeeding in Infancy Decreases Systolic Hypertension Risk in Young Adults

.L., Stampfer M.J., Birth weight and adult hypertension, diabetes mellitus, and obesity in US men. Circulation, 1996b, 94, 3246-3250. 12. Fall C.H.D., Borja J.B., Osmond C., Richter L., Bhargava S.K., Martorell R., Stein A.D., Barros F.C., Victoria C.G., COHORTS group, Infant-feeding patterns and cardiovascular risk factors in young adulthood: data from five cohorts in low- and middle- -income countries. Int. J. Epidemiol., 2011, 40, 47-62. 13. Fewtrell M.S., Breast-feeding and later risk of CVD and obesity: evidence from randomized trials

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Vitamīnu satura izmaiņas pilngraudu rudzu maizes ražošanā / Changes in Vitamin Content during the Whole Grain Rye Bread Processing

. Schatzkin, A., Lanza, E., Corle, D., Lance, P., Iber, F., Caan, B., ... Slattery, M. (2000). Lack of effect of a low-fat, high-fiber diet on the recurrence of colorectal adenomas. New England Journal of Medicine, 342, 1149-1155. 27. Seal, C.J. (2006). Whole grains and CVD risk. Proceedings of the Nutrition Society , 65, 24-34. 28. Ward, J., Poutanen, K., Gebruers, K., Piironen, V., Lampi, A.-M., Nystrom, L., ... Shewry, P. R. (2008). The HEALTHGRAIN cereal diversity screen: Concept, results and prospects. Journal of Agricultural and

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