Darina Drozdová, Zuzana Danková, Veronika Čerňanová and Daniela Siváková
The aim of this study was to analyse differences in body composition of women with and without cardiovascular complications. Bioelectrical parameters were measured with bioimpedance monofrequency analyser (BIA 101) and tissue electric properties were analysed by bioelectric impedance vector analysis (BIVA). The clinical sample (with CVD) consisted of 254 women ranging in age between 39 and 65 years. The sample of women without CVD consisted of 318 women in the same age range and was created from database of our previous studies. Statistical analysis adjusted for age showed significant differences in body composition characteristics of the studied samples. The results of vector analysis showed significantly different tissue electric properties of women in studied groups, what was confirmed by the Hotelling T2- test (p=0.0000). More women with CVD attained risky mean values of obesity indices of BMI and WHR than their “healthy” counterparts. Among women with CVD 80.2% had higher value of the BMI index than optimal one (>24.9 kg/m2) and 74.4% of women had higher value of the WHR index than optimal (>0.80). From the BIA parameters strong correlation coefficient was found between BMI and FM in both groups (r=0.962 for women with CVD; r=0.968 for relatively healthy women). Our data confirmed that cardiovascular disease complications are strongly linked in body composition changes. The cross-sectional nature of our study makes it difficult to draw conclusions regarding causal pathways, though variables of obesity are in line with unhealthy conditions.
The metabolic syndrome (MetS) is an important group of components responsible of high incidence of cardio-vascular disease (CVD) and stroke among the type 2 diabetic mellitus (DM) patients. Studies on the prevalence of the MetS and its components among DM patients are limited in developing countries and such studies never been done in Syria before. The objectives of current study were two-folds: (a) to investigate the prevalence of MetS in a group of DM Syrian patients as defined by NCEP-ATP III and IDF diagnostic criteria, and (b) to identify the individual MetS associated risk factors components in the studied group. A cross-sectional study carried out at one of the diabetic clinics of the health ministry in Damascus, Syria between 2016–2017. A random sample of 424 patients (209 males, 215 females) DM patients aged 40–79 years were participated in this study. Anthropometric indices, blood pressure (BP), fasting blood sugar (FBS), total cholesterol, high density lipoprotein cholesterol (HDL-C), triglycerides (TG) were determined. The overall prevalence of the MetS was 67% and 69.3% according to the NCEP-ATP III and IDF criteria, respectively. The prevalence was higher in females and increased with age. According to NCEP/ATP III criteria and for the overall group, high TG was the most prevalent component of the MetS. However, when an IDF criterion was applied, central obesity was the commonest component in the overall group. According to both diagnostic criteria, hypertension was significantly higher in males while central obesity was dominated in females (p<0.05, p<0.001, respectively). In conclusion, the results revealed high prevalence of the MetS in DM Syrian patients using both diagnostic criteria but slightly higher with IDF criteria. Especial care, health awareness, life style modifications, and proper medications should be directed towards controlling the risk factors components of this syndrome.
Early epidemiological studies demonstrated that short stature is associated with cardiovascular disease (CVD), diabetes, lower energy intake or food deprivation during growth, poor health, and increased all-cause mortality. Nevertheless, the links between adult height and longevity become tenuous if certain confounders (e.g. BMI, SES, educational attainment, etc.) are allowed for. Furthermore, numerous studies have found that like excess weight, tallness is costly in terms of longevity in late ontogeny, and shorter people tend to outlive their taller peers, especially if they are slim and maintain a healthy diet and lifestyle. Therefore, there is currently a lack of agreement in the literature as to whether and how body height and lifespan are linked. The objective of this study was to explore the relationship between adult stature and longevity on the basis of a large sample from a population-based cohort study. Data on declared height and exact dates of birth and death were available from 480,493 men and 364,666 women who died in the years 2004-2008 in Poland. To control for secular changes, the sample was divided into fifteen birth cohorts and each group was subsequently split into five height categories using pentiles, separately for both sexes. The analysis has revealed an inverse relationship between height and lifespan in men and women. However, after controlling for secular changes in height, the relationship turned out to be very weak and linear in men, and inverted U-shaped in women. In general, taller individuals had lower age at death compared to shorter ones, and this relationship was more pronounced and consistent in men. To sum up, these findings do not comport with the traditional belief that taller individuals live longer. The role of several possible biological mechanisms pertinent to enhanced longevity in smaller individuals was emphasized, and these biological factors were discussed.