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Open access

Dan Monea, Rodica Prodan and Vlad Teodor Grosu


Background. The purpose of the study was to realize the priorities in physical, technical and tactical training for junior football players. Moreover, preparing of the content was intended to optimize the use the most efficient methods and means for increasing the efficiency of speed and skill during the training and games.

Objectives. Data were collected from 18 junior football players, with ages ranging from 14-15 years, members of the ACS Unirea (C) Tritenii de Jos team. The subjects were tested three times during the whole training stage, pre, middle and post-training examinations being performed. The three examinations consisted of 5 tests each: 50-meter sprint, standing long jump, 2000 meter running, maintaining the ball in the air and leading the ball through markers.

Methods. Specific methods for developing the speed used in the study are based on repetitions (specific efforts at maximum or submaximal speed, under usual, relieved, severe conditions), on various efforts and intervals. Skill development methods took into account the complexity of coordinating action movements and the spatial, temporal, and motion force precision. For developing motor skills, the authors used the interval and circuit training.

Results. All the participants attained higher levels of performance, both at the second and third examination, on each of the 5 tests. Data collected were analyzed using the One –Way ANOVA statistical procedure, which compares the results obtained by one single group of subjects. This procedure revealed, at a significant level of confidence, that the mean of the performance enhancement reached 50 percents along the one-year training stage.

Conclusions. The research has shown that, by giving a more significant share of the best methods and means for developing the speed and skill in the physical training of junior footballers, the increase in the performance of these motor skills is significant.

Open access

Zoran Jovanovic, Vesela Radonjic, Ratomir Jelic, Narcisa Petrovic-Subic, Ivan Soldatovic, Vera Terzic, Sladjan Stojilkovic and Dusan Djuric


Apart from providing knowledge on the beneficial effects of drugs, practical psychopharmacotherapy also includes drug profiles of adverse effects, especially when medical comorbidity is present. The mechanism of action of many psychotropic drugs, mainly antipsychotics and antidepressants, is associated with prolongation of the QT interval and the occurrence of arrhythmias, specifically Torsade de pointes (TdP), which can be lethal. The aim of this pilot study was to confirm the prevalence of prolonged QTc interval in a sample of psychiatric patients taking psychopharmacs.

The present study included 41 patients who were already on psychopharmacs. The average value of the QTc interval in the observed sample was 413.8±23.3 ms. The most frequent psychopharmacotherapy was the combination of typical and atypical antipsychotics (24.4%), followed by monotherapy with antipsychotics (22%) and combined antidepressant and atypical antipsychotic therapy (22%). The average value of the QTc interval for male patients was 412.1±25.2 ms, whereas for female patients, it was 416.6±20.4 ms. No difference between sexes was confirmed (p=0.555). The correlation between the QTc interval and age of patients was positive but not statistically significant (p=0.072). The highest average (419.3±31.6 ms) and highest maximum (479 ms) values of the QTc interval were noted for patients undergoing combined therapy of antidepressants and atypical antipsychotics. Prolonged values of the QTc interval were observed for seven males and one female, and no patients exhibited pathological values.

This study confirmed previous research that found that prolongation of the QTc interval exists in patients in sample groups who take psychopharm acs, but not up to critical values.

Open access

Magdalena Babińska, Jerzy Chudek, Elżbieta Chełmecka, Małgorzata Janik, Katarzyna Klimek and Aleksander Owczarek


The aim of this study was to evaluate the possibility of incorrect assessment of mortality risk factors in a group of patients affected by acute coronary syndrome, due to the lack of hazard proportionality in the Cox regression model. One hundred and fifty consecutive patients with acute coronary syndrome (ACS) and no age limit were enrolled. Univariable and multivariable Cox proportional hazard analyses were performed. The proportional hazard assumptions were verified using Schoenfeld residuals, χ2 test and rank correlation coefficient t between residuals and time. In the total group of 150 patients, 33 (22.0%) deaths from any cause were registered in the follow-up time period of 64 months. The non-survivors were significantly older and had increased prevalence of diabetes and erythrocyturia, longer history of coronary artery disease, higher concentrations of serum creatinine, cystatin C, uric acid, glucose, C-reactive protein (CRP), homocysteine and B-type natriuretic peptide (NT-proBNP), and lower concentrations of serum sodium. No significant differences in echocardiography parameters were observed between groups. The following factors were risk of death factors and fulfilled the proportional hazard assumption in the univariable model: smoking, occurrence of diabetes and anaemia, duration of coronary artery disease, and abnormal serum concentrations of uric acid, sodium, homocysteine, cystatin C and NT-proBNP, while in the multivariable model, the risk of death factors were: smoking and elevated concentrations of homocysteine and NT-proBNP. The study has demonstrated that violation of the proportional hazard assumption in the Cox regression model may lead to creating a false model that does not include only time-independent predictive factors.

Open access

Linda A. Jacobsen

5. References Baumgardner, S.K., D.H. Griffin, and D.A. Raglin. 2014. “The Effects of Adding an Internet Response Option to the American Community Survey.” 2014 American Community Survey Research and Evaluation Report Memorandum Series #ACS14-RER-21, U.S. Census Bureau, Washington, DC. Available at: (accessed October 2017). Erdman, C. and N. Bates. 2014. “The U.S. Census Bureau Mail Return Rate Challenge: Crowdsourcing to Develop a Hard-to-Count Score

Open access

Nikoletta Godová and Blažej Horváth

References Angelici C, Velthoen MEZ, Weckhuysen BM, Bruijnincx PCA (2015) Catalysis Science and Technology 5: 2869-2879. Bi J, Guo X, Liu M, Wang X (2010) Catalysis Today 149: 143-147. Chieregato A, Ochoa JV, Cavani F (2016) Olefins from Biomass, in Chemicals and Fuels from Bio-Based Building Blocks (eds F. Cavani, S. Albonetti, F. Basile and A. Gandini), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany, ISBN: 9783527698202. DeWilde JF, Czopinski ChJ, Bhan A (2014) ACS

Open access

Mehmet Can Ugur, Ferhat Ekinci, Utku Erdem Soyaltın and Harun Akar


Introduction. Contrast-induced nephropathy (CIN) is associated with increased morbidity and mortality after percutaneous coronary intervention (PCI). On the other hand, CIN is a serious complication in patients with diabetes or renal impairment undergoing percutaneous coronary intervention (PCI). CIN after PCI may be associated with prolonged hospitalization, increased rates of kidney injury, and short- and long-term mortality. Factors that have been associated with CIN include: diabetes mellitus, congestive heart failure, recent acute myfocardial infarction, cardiogenic shock, and pre-existing renal impairment. In this study, we investigated contrast nephropathy development after coronary angiography (CAG) in patients presenting with acute coronary syndrome, who were hospitalized initially in the Coronary Care Unit and subsequenttly referred to the Internal Medicine Clinic in a tertiary care hospital.

Methods. We’ve analyzed 335 patients’ records retrospectively in 1 year that were followed-up with acute coronary syndrome (ACS) in the Coronary Care Unit (CCU) and transferred to the Internal Medicine Clinic (IMC). The following parameters were evaluated: age, gender, chronic disease and drug history, biochemical values evaluated before hospitalization to CCU, ejection fraction (EF) and left atrium diameter (LA), with or without previous CAG; values of serum creatinine (sCr) levels before CAG and after 48 hours. Values of p <0.05 were considered to be significant.

Results. 126 of 335 patients were female and 209 were male. The average age of patients was 64.2 years. 122 patients used angiotensin converting enzyme inhibitor (ACEI), 54 patients used furosemide. CIN development rate of CAG patients was 22.8% (n=54). There was no significant relationship with age, gender and chronic disease history in CIN patients. When laboratory findings were compared, there was no significant relationship except for potassium value before CAG. However, potassium values were significantly higher in CIN patients (p=0.001). When drug usage of patients was compared, 48.1% (n=26) of CIN patients used ACEI and there was a significant relationship between ACEI use and CIN development (p=0.026).

Conclusions. CIN development rate was 22.8% and it was relatively high when compared with literature data. Awareness about contrast nephropathy develepment risk and assessment of risk factors before the procedure should be increased in our Center.

Open access

G. Ikaunieks, M. Ozolinsh, A. Stepanovs, V. Lejiete and N. Reva


Our vision in the twilight or dark is strongly affected by the intraocular light scattering (straylight). Of especial importance is to assess this phenomenon in view of the night driving. The authors have studied the spectral dependence of retinal stray-light and estimated the possibility to reduce it with yellow filters and small apertures. For the measurements the direct compensation flicker method was used. The results show that this spectral dependence is close to Rayleigh's scattering (∝λ-4). As could be expected from the known data, the yellow filter should reduce retinal straylight, especially for blue light. However, in the experiments this scattering was not removed with such a filter but instead slightly increased. The optical apertures reduced light scattering in the eye, especially for red color.

Open access

Jiří Novosák and Radek Jurčík

References Acs Z.J., How is entrepreneurship good for economic growth? Innovations, 1(1)/2006, pp. 97–107. Acs, Z.J., Desai, S., Hessels, J., Entrepreneurship, economic development and institutions. Small Business Economics, 31(3)/2008, pp. 219–234. Allen I.E., Langowitz N., Minniti M., Global Entrepreneurship Monitor. 2007 Report on Women and Entrepreneurship, Wellesley: Babson College 2008. Audretsch D.B., Entrepreneurship: a Survey of the Literature, Luxembourg: Publications Office of the European Union 2011. Calinski T., Harabasz

Open access

Z. Adamiak, P. Jastrzębski, A. Pomianowski, I. Otrocka-Domagała, P. Holak, Y. Zhalniarovich, P. Przyborowska and J. Głodek

References Arnaud F, Teranishi K, Tomori T, Carr W, McCarron R (2009) Comparison of 10 hemostatic dressings in a groin puncture model in swine. J Vasc Surg 50: 632-639. Arnaud F, Tomori T, Carr W, McKeague A, Teranishi K, Prusaczyk K, McCarron R (2008) Exothermic reaction in zeolite hemostatic dressings: QuikClot ACS and ACS +. Ann Biomed Eng 36: 1708-1713. Devlin JJ, Kircher S, Kozen BG, Littlejohn LF, Johnson AS (2011) Comparison of ChitoFlexR, CeloxTM, and Quik- ClotR in control of hemorrhage. J Emerg Med 41

Open access

Ludmila Fedorchenko and Sergey Baranov

References 1. Aho, A., R. Sethi, J. Ullman. Compilers: Principles, Techniques and Tools. Addison- Wesley, 1986. 2. Fedorchenk o, L. An Algorithm of Parsing Languages Generated with R-Grammars. – In: Algorithms and Systems for Research Automation. Moscow, Nauka, 2008, 15-20 (in Russian). 3. Fedorchenko, L. Syntax Graph Transformations in the System SynGT and Regularization of Grammars. – In: International Multi- Conference on Advanced Computer Systems (ACS-CISIM'2004), 14-16 June 2004, Elk, Poland. 4. Fedorchenko, L. On