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Hypercalcemia in Patients Treated with Oral Bisphosphonates for Tumor-Induced Osteolysis

;62:6538-44. 28. Lahtinen R, Laakso M, Palva I, Virkkunen P, Elomaa I.Randomised, placebo-controlled multicentre trial of clodronate in multiple myeloma. Finnish Leukaemia Group. Lancet. 1992; 340:1049-52. 29. Yuen KK, Shelley M, Sze WM, Wilt T, Mason MD.Bisphosphonates for advanced prostate cancer. Cochrane Database Syst Rev. 2006;4:CD006250.

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Epidemiological, Clinical, Molecular Features and Early Detection Strategy of Most Frequent Hereditary Cancers in Latvia

patients with familial adenomatous polyposis (FAP). Human Mutation: Mutation in Brief , No. 705, Boltenberg, A., Furgyik, S., Kullander, S. (1990). Familial cancer agregation in cases of adenocarcinoma corporis uteri. Acta Obstet. Gynecol. Scand. , 69 , 249-258. Bratt, O. (2000). Hereditary prostate cancer. BJU Int.   85 (5), 588-98. Bülow, S

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Toward a better prescription method for external radiotherapy

;52(1):224-235. [10] ICRU. Prescribing, recording, and reporting photon-beam intensity-modulated radiation therapy (IMRT). ICRU Report 83. J ICRU. 2010;10(1):1-106. [11] Mrozowska M, Kukołowicz P. Relationships between various indices of doses distribution homogeneity. Rep Pract Oncol Radiother. 2015;20(4):278-283. [12] Miles EF, Nelson JW, Alkaissi AK, et al. Biologically effective dose (BED) correlation after low-dose rate prostate brachytherapy for clinically low-risk prostate cancer. Int J Radiat Oncol Biol Phys. 2010;77(1):139-146. [13] Hartley A, Sanghera P

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Low-Intensity Extracorporeal Shockwave Therapy – A New Approach in the Treatment of Erectile Dysfunction after Radical Prostatectomy

References 1. Hatzimouratidis K, Burnett AL, Hatzichristou D, McCullough AR, Montorsi F, Mulhall JP. Phosphodiesterase type 5 inhibitors in postprostatectomy erectile dysfunction: a critical analysis of the basic science rationale and clinical application. Eur Urol. 2009;55(2):334-47. 2. Dimitrov P, Panchev P, Simeonov P, Vasilev V, Georgiev M, Yanev K. Prostate carcinoma - staging and possibilities for operative treatment. Medical science. 2008;2:51-5. 3. Walsh PC. Radical prostatectomy for localized prostate cancer provides durable cancer

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Impact of body-mass factors on setup displacement during pelvic irradiation in patients with lower abdominal cancer

was approved by the local Institutional Review Board (CMUH106-REC3-119). Patients were divided into two cohorts (60 for training, 30 for validation). In the training cohort, patients with gynecological (cervix or endometrium), rectal, or prostate cancer treated with pelvic irradiation by daily IGRT between January 2012 and January 2015 at China Medical University Hospital were included. The sample size for gynecological, rectal, and prostate cancers was 20 each. The patient-related parameters and BMFs were retrieved. Staging was based on the staging system (7 th

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The effects of Curcuma longa and curcumin on reproductive systems

. Th erapeutic potential of curcumin in human prostate cancer. III. Curcumin inhibits proliferation, induces apoptosis, and inhibits angiogenesis of LNCaP prostate cancer cells in vivo. Prostate 47, 293-303, 2001. Eigner D, Scholz D. Ferula asa-foetida and Curcuma longa in traditional medical treatment and diet in Nepal. J Ethnopharmacol 67, 1-6, 1999. Farombi EO, Abarikwu SO, Adedara IA, Oyeyemi MO. Curcumin and kolaviron ameliorate di‐n‐butylphthalate‐induced testicular damage in rats. Basic Clin Pharmacol Toxicol 100

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BRCA1/2 associated cancer susceptibility: a clinical overview

third-degree blood relative (on the same side of the family) diagnosed with breast and/or epithelial ovarian/fallopian tube/primary peritoneal cancer ≤50 years Diagnosed at any age with ≥2 first-, second-, or third-degree blood relatives (on the same side of the family) with breast and/or epithelial ovarian/ fallopian tube/primary peritoneal cancer at any age Diagnosed at any age with ≥2 first-, second-, or third-degree blood relatives (on the same side of the family) with pancreatic cancer or aggressive prostate cancer (Gleason score ≥7) at any age First

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The Morpho-Functional Parameters of Rat Pituitary Hormone Producing Cells After Genistein Treatment

Los Angeles County. Br J Cancer. 63, 963-966. PMid:2069852 PMCid:PMC1972548 24. Watanabe, S., Koessel, S (1993). Colon cancer: an approach from molecular epidemiology. J Epidemiol. 3, 47-61. 25. Severson, R.K., Nomura, A.M., Grove, J.S., Stemmermann, G.N. (1989). A prospective study of demographics, diet, and prostate cancer among men of Japanese ancestry in Hawaii. Cancer Res. 49, 1857-1860. PMid:2924323 26. Anthony, M.S., Clarkson, T.B., Hughes, C.L.Jr., Morgan, T.M., Burke

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18F-FET and 18F-FCH uptake in human glioblastoma T98G cell lines

patients with gliomas. 4 - 6 18 F-fluorodeoxyglucose ( 18 F-FDG) Positron Emission Tomography (PET) in brain tumours was the first application of this modality in oncology 7 , 8 , however because of the high physiologic glucose uptake of normal brain tissue, 18 F-FDG did not gain widespread use in brain tumours imaging. 9 , 10 PET imaging with [ 11 C]- and [ 18 F]-labelled choline derivates is frequently used in the staging and detection of recurrent prostate cancer disease due to the increased choline kinase expression in this malignancy. Moreover, choline kinase

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Pharmacological activities of some triazinopyrazolothieno pyrimidine derivatives


Triazinopyrazolothieno pyrimidine derivatives 1–5 were evaluated for their anti-inflammatory, analgesic and anticancer activities and acute toxicity. Anti-inflammatory activity of the compounds was studied using the carrageenan test. All tested compounds showed analgesic activity, 3-methoxycarbonyl-4,6-dimethyl-8-[(N-methylindolyl)methyl] pyrimido [5′,4′:4,5]thieno [3′,2′-3,4]pyrazolo [5,1-c]triazine (4) showed activity comparable to that of diclofenac. Compounds 1–5 were also screened for anticancer activity on a human lung cancer cell line (A549) and a human prostate cancer cell line (DU145) using the MTT micro-cultured tetrazolium assay method. Compound 4 showed also significant anticancer activity against both cancer cell lines, comparable to that of doxorubicin. The most active compounds were tested for their acute toxicity and median lethal doses were evaluated.

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