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Yeltay Rakhmanov, Paolo Enrico Maltese, Stefano Paolacci, Francesca Fanelli, Tommaso Beccari, Munis Dundar and Matteo Bertelli

endocardial cushion defect in families. Am J Cardiol 1985; 55(13 Pt 1): 1649-52. 5. Digilio MC, Marino B, Cicini MP, Giannotti A, Formigari R, et al. Risk of congenital heart defects in relatives of patients with atrioventricular canal. Am J Dis Child 1993; 147(12): 1295-97. 6. Digilio MC, Marino B, Giannotti A, Dallapiccola B. Familial atrioventricular septal defect: possible genetic mechanism. Br Heart J 1994; 72(3): 301. 7. Cousineau AJ, Lauer RM, Pierpont ME, Burns TL, Ardinger RH, Patil SR, Sheffield VC. Linkage analysis of autosomal dominant

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Harikrishna Naik Lavudi, Seshagirirao Kottapalli and Francisco M. Goycoolea

beads for gastrointestinal drug delivery. Journal of Applied polymer Science 2001; 82: 3084-3090. 11. Kapoor VP, Milas M, Taravel FR, Rinaudo M. Rheological properties of seed galactomannan from Cassia nodosa buch.-hem. Carbohydrate Polymers 1994; 25: 79-84. 12. Srivastava M, Kapoor VP. Seed galactomannans: an overview. Chemistry & Biodiversity 2005; 2: 295-317. 13. Cerqueira MA, Bourbon A, Pinheiro A, Martins J, Souza B, Teixeira J, Vicente AA. Galactomannans us in in the development of edible films/coatings for food

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Kevan M.A. Gartland and Jill S. Gartland

. Gartland KMA. Responding to climate change: barriers to progress and green opportunities. Biochemist 2006; October 54-55. 13. Ruane J, Sonnino A. Agricultural biotechnologies in developing countries and their possible contribution to food security. J. Biotechnol. 2011; 156: 356-363. 14. Gartland KMA, Gartland JS. Green biotechnology for food security in climate change. Reference Module in Food Sciences 2016; Elsevier pp.1-9. http://dx.doi.org/10.1016/B978-0-08-100596-5.03071-7 15. US National Academies of Sciences

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Nathalie Picollet-D’hahan, Axel Tollance, Cristina Belda Marin, Lavinia Liguori, Christophe Marquette, Odile Filhol-Cochet, Isabelle Vilgrain, Guillaume Laffitte, Florence Rivera, Jean-Pierre Alcaraz, Jacques Thélu, Olivier Nicoud, Thibaud Moufle-Milot, Maxime Legues, Ali Bouamrani, Adrien Mombrun, Benoit Gilquin, Sophie Gerbaud, Patricia Obeid, Fréderique Kermarrec, Xavier Gidrol and Donald K. Martin

References 1. Vidi P-A, Bissell MJ, Lelievre SA. Three-Dimensional Culture of Human Breast Epithelial Cells: The How and the Why. Methods Mol Biol. 2013;945:193-219. 2. Mosaad EO, Chambers KF, Futrega K, Clements JA, Doran MR. The Microwell-mesh: A high-throughput 3D prostate cancer spheroid and drug-testing platform. Sci Rep. 10 janv 2018;8(1):253. 3. Picollet-D’hahan N, Dolega ME, Freida D, Martin DK, Gidrol X. Deciphering Cell Intrinsic Properties: A Key Issue for Robust Organoid Production. Trends Biotechnol

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Martin Koller

, Peters RJ. Potential health impact of environmentally released micro-and nanoplastics in the human food production chain: experiences from nanotoxicology. Environ Sci Technol 2015; 49(15): 8932-8947. 11. Online resource 4: Last accessed October 24th, 2018 (in German) https://derstandard.at/2000089947285/Frage-und-Antwort-Wie-Mikroplastik-in-den-Organismus-gelangt . 12. Jia P, Xia H, Tang K, Zhou Y. Plasticizers derived from biomass resources: a short review. Polymers 2018; 10(12): 1303. 13. Zhu Y, Romain C, Williams CK. Sustainable polymers from

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Antonija Trontel, Anita Slavica, Mario Novak, Nuša Jelovac, Srđan Novak and Božidar Šantek

-74. 11. Le Boucher J, Charret C, Coudray-Lucas C, Giboudeau J, Cynober L. Amino acid determination in biological fluids by automated ion-exchange chromatography: performance of Hitachi L-8500A. Clinical Chem 1997; 43: 1421-28. 12. Salazar C, Armenta JM, Cortes DF, Shulaev V. Combination of an AccQ・Tag-Ultra Performance Liquid Chromatographic Method with Tandem Mass Spectrometry for the Analysis of Amino Acids, in Alterman, MA, Hunziker P. (Ed), Amino Acid Analysis: Methods and Protocols, Methods in Molecular Biology, vol. 828, Springer, 2012, pp. 13

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Stefano Paolacci, Yeltay Rakhmanov, Paolo Enrico Maltese, Francesca Fanelli, Raul Ettore Mattassi, Bruno Amato and Matteo Bertelli

, Vikkula M. Variable somatic TIE2 mutations in half of sporadic venous malformations. Mol Syndromol 2013; 4(4): 179-183. 12. Castel P, Carmona FJ, Grego-Bessa J, Berger MF, Viale A, Anderson KV, Bague S, Scaltriti M, Antonescu CR, Baselga E, Baselga J. Somatic PIK3CA mutations as a driver of sporadic venous malformations. Sci Transl Med. 2016; 8(332): 332ra42. 13. Brouillard P, Boon LM, Mulliken JB, Enjolras O, Ghassibé M, Warman ML, Tan OT, Olsen BR, Vikkula M. Mutations in a novel factor, glomulin, are responsible for glomuvenous malformations

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Kizukala Jamir and Seshagirirao Kottapalli

Zingiberaceae rhizomes. Afr J Tradit Complement Altern Med 2014; 11(3): 7-13. 24. Ghasemzadeh A, Jaafar HZE, Rahmat A. Antioxidant Activities, Total Phenolics and Flavonoids Content in Two Varieties of Malaysia Young Ginger (Zingiber officinale Roscoe). Molecules 2010; 15: 4324-4333. 25. Ozturk M, Ozturk FA, Duru ME, Topcu G. Antioxidant activity of stem and root extracts of Rhubarb (Rheum ribes): An edible medicinal plant. Food Chem 2007; 103: 623-630. 26. Mylonas C, Kouretas D. Lipid peroxidation and tissue damage. In Vivo

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Andi Abeshi, Francesca Fanelli, Tommaso Beccari, Munis Dundar, Benedetto Falsini and Matteo Bertelli

. Invest Ophthalmol Vis Sci. 2003 Aug; 44(8):3570-7. PubMed PMID: 12882809; PubMed Central PMCID: PMC2581458. 12. Apfelstedt-Sylla E, Theischen M, Ruther K, Wedemann H, Gal A, Zrenner E. Extensive intrafamilial and interfamilial phenotypic variation among patients with autosomal dominant retinal dystrophy and mutations in the human RDS/peripherin gene. Br J Ophthalmol. 1995 Jan; 79(1):28-34. PubMed PMID: 7880786; PubMed Central PMCID: PMC505014. 13. Boon CJ, van Schooneveld MJ, den Hollander AI, van Lith-Verhoeven JJ, Zonneveld-Vrieling MN

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Danuta Plotnikava, Anastasiya Sidarenka and Galina Novik

resistance in lactic acid bacteria from food. Antonie Van Leeuwenhoek 1999; 76(1-4): 115-37. 11. Drake JW, Charlesworth B, Charlesworth D, Crow JF. Rates of spontaneous mutation. Genetics 1998; 148(4): 1667-86. 12. Khachatourians GG. Agricultural use of antibiotics and the evolution and transfer of antibiotic-resistant bacteria. CMAJ Can Med Assoc J 1998; 159(9): 1129-36. 13. Wang HH, Manuzon M, Lehman M, Wan K, Luo H, Wittum TE, et al. Food commensal microbes as a potentially important avenue in transmitting antibiotic