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Panruethai Trinavarat, Pantipa Chatchatri and Poonchavist Chandtranuwatana

Abstract

Background: Pulmonary aspergillosis may be the first presentation of chronic granulomatous disease (CGD) and may occur during infancy. Imaging studies with plain chest radiographs and computed tomography may present a diagnostic challenge, and high index of suspicion is required for the diagnosis.

Objective: Report a six-week-old boy with chronic granulomatous disease and invasive pulmonary aspergillosis, in who color Doppler sonography of the chest showed systemic arterial supply to the pulmonary lesions.

Methods: Sonography of the chest using a high-frequency linear transducer was performed in a six-week-old infant with chronic granulomatous disease who presented with noisy breathing, cough, and low-grade fever, and his chest radiograph revealed multiple sites of pulmonary opacities.

Results: The peripheral pulmonary nodules had low-resistant arterial supply derived from a systemic artery of the chest wall. The pulmonary lesion was later proven to be fungal infection. Similar imaging was detected in another two infants with the same disease.

Conclusion: Systemic arterial supply could develop to feed peripheral pulmonary aspergillosis in an infant as young as six-week old who had underling CGD.

Open access

A Strajnar, MZ Tansek, KT Podkrajsek, T Battelino and U Groselj

respond to diazoxide therapy, only very rarely is a pancreatectomy needed [ 21 ]. Our patient has now been on therapy for more than 1 year, without documented hypoglycemia or seizures and with normal growth and development. Conclusions . It is important to always consider hypoglycemia and hyperammonemia when a baby “is not well,” as symptoms may not be specific. If transient hypoglycemia in an infant is ruled out, metabolic disorders must be taken into account. In HI/HA syndrome, diazoxide is the first line of treatment; hypoglycemia is well controlled and

Open access

Rakesh Kumar, Amit Chanduka, Devendra Purohit, Radhe Shyam Mittal and Ronyl Kaushal

Abstract

Spinal Teratomas are rare tumor and cervical intramedullary location in infancy still rarer. Only eleven cases of cervical intramedullary teratoma in pediatric patients is reported in available literature (1, ll). We are reporting a case of an infant presenting with cervical mature teratoma with associated dysraphism, adding the next in this rare case series. Arising as a result of dysembryogenesis, these lesions by virtue of their content are difficult to diagnose preoperatively. Heterogeneous intensities on MRI produced by intralesional lipomatous and osseous elements are helpful but rarely enough to diagnose the tumor. Histology is confirmatory. Mature teratomas generally have good prognosis and a timely intervention can prevent further neurological deterioration. However a strict clinical and radiological follow up is recommended.

Open access

Natasa Ristic, Vladimir Ajdzanovic, Svetlana Trifunovic, Nasta Tanic, Nada Bujisic and Verica Milosevic

Abstract

The effects of estradiol-dipropionate (EDP) or human chorionic gonadotropin (hCG) on immunohistomorphometric characteristics of pituitary GH cells in infant and peripubertal female rats were investigated. The first group of females received five injections of EDP (0.25 mg/kg b.w.) during the neonatal period of life, and was further divided into two subgroups which were sacrificed at the infantile period (17th day) or at the peripubertal period (38th day). The second group received two doses of hCG (50 IU/kg b.w.) on the 15th and 16th day of life in the first subgroup, and on the 36th and 37th days of life in the second subgroup, while they were sacrificed 24 h after the last treatment, respectively. The control females were injected with an equivalent volume of the vehicle and sacrificed according to the appropriate schedules as the hormone treated rats. EDP treatment decreased GH cell volume density in infant and peripubertal females, by 38% and 76% (p<0.05) respectively, in comparison with the controls. The number of GH cells per mm2 in infantile and peripubertal period was decreased in EDP treated animals by 26% and 53% (p<0.05) respectively, compared to the controls. Also, upon EDP treatment in both periods, GH cells were diminished in size and less intensely immunolabelled than in the control groups. The morphometric parameters in animals treated with hCG were insignificantly changed in both analyzed periods, in comparison with the controls. Unlike hCG, EDP manifested clear inhibitory effects on the immunohistomorphometric characteristics of GH cells in examined female rats.

Open access

Bolesław Kuzaka, Dariusz Kawecki, Tomasz Borkowski, Joanna Broda, Zbigniew Wierzbicki, Piotr Małkowski, Andrzej Chmura and Andrzej Borkowski

An Analysis of Enterovesical Fistulas in Patients Hospitalized in Medical University of the Infant Jesus Hospital in Warsaw from 1995 to 2006

Enterovesical fistulas (EF) are a relatively uncommon complications of colorectal and pelvic malignancies, diverticulitis, inflammatory bowel disease, radiotherapy and traumas. Authors reviewed material of 24 patients hospitalized in the Jesus Infant Hospital Medical University of Warsaw from 1995 to 2006.

Material and methods. A total of 24 symptomatic fistulas were recorded in a 13 of women and 11 of men. In all cases of persistent fistulas were treated by surgical and/or urological interventions. The origin of the fistulas were: colorectal malignancies 16 of patients (67%), pelvic malignancies 2 patients (8%), vesical malignancies 3 patients (12.5%) and other 3 patients (12.5%). The most common anatomical anastomoses were as follows: vesicosigmoidal fistula in 12 patients (50%), vesicorectal fistula in 4 patients (16.5%), vesicoenteral fistula in 2 patients (8.5%), urogenitoenteral fistula in 3 patients (12.5%), other in 3 patients (12.5%).

Results. Surgical treatment of fistulas were: colostomy in 15 patients (50%), enteral resections and anastomoses in 6 patients (20%), transversostomy 3 patients (10%), jejunostomy 1 patient (3%), other in 5 patients (17%). To the end of 2006 from 24 patients underwent of treatment : 9 patients are alive (37.5%), 8 patients death (33.3%), 7 unknown (29.2%). The median period of life were 12 months (from 1 to 84 months) after.

Conclusions. 1. The most common etiological factors of enterovesical fistulas were colorectal malignancies 67% of patients. 2. Only 20% of patients were underwent completly surgical treatment because of advenced malignancies. 3. The most common method of surgical treatment was colostomy in 63% of patients.

Open access

Patricia D. Oulai, Lessoy T. Zoué and Sébastien L. Niamké

Abstract

The aim of this study was to evaluate the effect of steam blanching processing on the nutritive value and the antioxidant properties of five leafy vegetable species (Amaranthus hybridus, Andasonia digitata, Ceiba patendra, Hibiscus sabdariffa and Vigna unguiculata) that are used for sauce preparation in Northern CÔte d'Ivoire. The selected leafy vegetables were subjected to blanching in pressure cooker for 15, 25 and 45 min and the physicochemical properties were determined using AOAC methods. The result of the study revealed that longer time of blanching (higher than 15 min) caused negative impact by reducing nutritive value but positive impact by reducing anti-nutrients and increasing polyphenols. The registered losses (p0.05) at 15 min were as follow: ash (0.08-10.01%), proteins (0.36-12.03%), vitamin C (19.56-68.67%), carotenoids (18.91-55.48%) oxalates (3.58-21.39%) and phytates (10.51-68.02%). The average increase of polyphenols contents at 15 min of blanching was 1.61 to 30.72%. In addition, a slight increase (0.35-4.16%) of fibres content was observed in the studied blanched leafy vegetables. Furthermore, after 15 min of blanching time the residual contents (p0.05) of minerals were: calcium (264.88-844.92 mg/100 g), magnesium (49.45-435.43 mg/100 g), potassium (675-1895.41 mg/100 g), iron (14.54-70.89 mg/100 g) and zinc (9.48-36.46 mg/100 g). All these results suggest that the recommended time of domestic blanching must be less than 15 min for the studied leafy vegetables in order to contribute efficiently to the nutritional requirement and to the food security of Ivorian population

Open access

Anda Vilmane, Inga Ziemele, Santa Rasa, Anna Terentjeva, Modra Murovska, Dace Gardovska, Yung-Cheng Lin and Zaiga Nora-Krūkle

Abstract

Lower respiratory tract infection (LRTI) is the major cause of morbidity and mortality of children in the world. In addition to respiratory syncytial virus, influenza virus types A and B, parainfluenza types 1, 2 and 3, and adenoviruses, several new respiratory viruses associated with LRTI were discovered in the 21st century. These are metapneumovirus, coronaviruses NL63 and HKU1, parainfluenza virus type four and human bocavirus one (HBoV1). HBoV1 was discovered in 2005 and is considered as the fourth most prevalent respiratory virus worldwide. However, the high frequency of co-infections detected together with HBoV1 raises doubt about whether HBoV1 is a true pathogen or just a bystander. This is the first study aimed to determine the presence of HBoV1 and 18 other respiratory viruses in nasopharyngeal aspirates (NPA) of children with LRTI in Latvia. Using multiplex real-time polymerase chain reaction method, the HBoV1 genomic sequence was detected in 60.0% of NPA samples, showing that HBoV1 prevalence is high among children with LRTI in Latvia. HBoV1 mono-infection was revealed in 6.67%. The most common co-infections associated with HBoV1 were rhinovirus, adenovirus, respiratory syncytial virus A and B, metapneumovirus, and enterovirus.

Open access

Kaewjai Thepsuthammarat, Bandit Thinkhamrop and Chanpen Choprapawon

children’s cognitive and social development from birth through third grade. Child Dev. 2005; 76:795-810. 4. Meio MD, Lopes CS, Morsch DS. Prognostic factors for cognitive development of very low birth weight premature children. Rev Saude Publica. 2003; 37:311-8. 5. Mackner LM, Black MM, Starr RH, Jr. Cognitive development of children in poverty with failure to thrive: a prospective study through age 6. J Child Psychol Psychiatry. 2003; 44:743-51. 6. Cooke RW. Perinatal and postnatal factors in very preterm infants and

Open access

Jolanta Stępowska, Agata Pudłowska, Anna Matlęga and Małgorzata Łukowicz

-33. 4. Pyzio-Kowalik M, Wójtowicz D, Skrzek A. Assessing postural asymmetry with a podoskope in infants with Central Coordination- Disturbance. Res Dev Disabil 2013;34(5):1832-42. 5. Yuge M, Marschik P, Nakajima Y, Kanda T, Hirota H, Yoshida N, Einspieler Ch. Movements and posture of infants aged 3 to 5 months. To what extent is their optimality related to perinatal events and to the neurological outcome. Early Hum Dev 2011;87(3): 231 6. Adamska A, Wójtowicz D, Ostrowska B. Ocena pozycji siedzącej u niemowląt w wieku 9 miesięcy przy