contribute to the development of portal vein thrombosis in patients with cirrhosis Thromb Res 2013 131 173 77
5 Zocco MA, Di Stasio E, De Cristofaro R, Novi M, Ainora ME, Ponziani F, et al . Thrombotic risk factors in patients with liver cirrhosis: Correlation with MELD scoring system and portal vein thrombosis development. J. Hepatol 2009;51: 682-9. 10.1016/j.jhep.2009.03.013 Zocco MA Di Stasio E De Cristofaro R Novi M Ainora ME Ponziani F Thrombotic risk factors in patients with liver cirrhosis: Correlation with MELD scoring system and portal vein thrombosis
significantly better than anticoagulants.
As ~25% of the population has a PFO, and only ~5.5% of strokes are due to paradoxical embolism, the PFO will be incidental in ~80% of all stroke patients and ~50% of those with ESUS. [ 45 ] The ROPE score [ 46 ] mentioned in the Editorial assesses the likelihood that a stroke is an embolic stroke of unknown source (ESUS).
There can be serious complications of percutaneous closure. These include embolization of the device, with fatal obstruction of the aortic valve, or embolization to distal arteries requiring emergency surgery
Francesco Montagnani, Greta Di Leonardo, Mariasimona Pino, Simona Perboni, Angela Ribecco and Luisa Fioretto
report the results.[ 15 ]
Six studies including 3407 patients were included. The trial flow chart is shown in Figure 1 . All patients had been previously administered bevacizumab. Except for CORRECT and CONCUR studies, which account for 964 patients, all patients had received only one previous line of treatment. Median age ranged from 55 to 62 years. All the studies carried a low risk of bias for overall survival analysis (Table 2) . With respect to progression-free survival, all studies were scored as low risk, with the exceptions of Bebyp and TML
influenza A/H1N1 pneumonia and acute respiratory distress syndrome Am J Respir Crit Care Med 2011 183 1200 – 6
25 Kim SH, Hong SB, Yun SC, Choi WI, Ahn JJ, Lee YJ, et al Corticosteroid treatment in critically ill patients with pandemic influenza A/H1N1 2009 infection: analytic strategy using propensity scores. Am J Respir Crit Care Med 2011; 183: 1207–14.
Kim SH Hong SB Yun SC Choi WI Ahn JJ Lee YJ et al Corticosteroid treatment in critically ill patients with pandemic influenza A/H1N1 2009 infection: analytic strategy using
Manuel E. Herrera-Gutiérrez, Gemma Seller-Pérez, Dolores Arias-Verdu and Manuel Delgado-Amaya
. Serum il-6 and il-1-ra with sequential organ failure assessment scores in septic patients receiving high-volume haemoflltration and continuous venovenous haemoflltration. Nephrology (Carlton) 2006;11:386-93.
79. Ronco C, Tetta C, Mariano F, Wratten ML, Bonello M, Bordoni V, et al. Interpreting the mechanisms of continuous renal replacement therapy in sepsis: The peak concentration hypothesis. Artif Organs 2003;27:792-801.
80. Honore PM, Matson JR. Extracorporeal removal for sepsis: Acting at the tissue level - the beginning of a new era
Ebada Said, Waleed El Agawy, Rehab Ahmed, Mohamed Hassany, Amal Ahmed, Hanan Fouad and Hosam Baiumy
Positive HBV DNA PCR [polymerase chain reaction] for ≥ 6 months) were included. All included patients were HBV genotype D.
Co-infection with HCV, hepatitis D virus (HDV), and human immunodeficiency virus (HIV);
Advanced liver fibrosis (fibroscan ≥ 12.5 kPa, liver biopsy ≥ F3 by Metavir score)
HCC or decompensated liver cirrhosis;
Those who were receiving medications known to affect vitamin D3 level or metabolism (calcium, vitamin D supplementation, oestrogen, alendronate, isonicotinic acid hydrazine [INH], Thiazide diuretics, long
Ilaria Botta, Jacques Devriendt, Jose Castro Rodriguez, Marielle Morissens, Andrew Carling, Leonel Barreto Gutierrez, Thierry Preseau, David De Bels, Patrick M. Honore and Sebastien Redant
nifedipine in a pregnant woman with unknown severe mitral stenosis.
Loop diuretics (furosemide) and full-dose heparin were administered once blood pressure was stabilized. Ultrasound examination showed no fetal distress. Transoesophageal echocardiography showed a severe rheumatic mitral stenosis with an estimated valve area of 0.5 cm 2 and a transmitral mean gradient of 25 mm Hg. The Wilkins score was 8, authorizing percutaneous valvuloplasty. [ 12 ]
However, soon after admission, spontaneous vaginal delivery occurred, before the valvuloplasty start.
The baby was
March (excluding those with pre-existing CHD, diabetes, stroke and/
or TIA), who have a recorded CVD risk assessment score (using an assessment
tool agreed with the NHS Commissioning Board) of ≥ 20% in the preceding 12
months: the percentage who are currently treated with statins
SMOK002. The percentage of patients with any or any combination of the
following conditions: CHD, PAD, stroke or TIA, hypertension, diabetes, COPD
CKD, asthma, schizophrenia, bipolar affective disorder or
Massimo Vincenzi, Irene Del Ciondolo, Elisa Pasquini, Katia Gennai and Barbara Paolini
bloating) to evaluate the severity of symptoms and VAS was repeated every 30 days.
The symptoms evaluated as per the validation questionnaire IBS-SSS (Irritable Bowel Syndrome, Severity Score System) were: abdominal pain intensity, abdominal pain frequency, abdominal distension, dissatisfaction with bowel habits, influence of IBS on life in general (“life interference”) and alterations in stool consistency.
After the enrollment, all the patients filled out a diary for 15 days to evaluate the number of days with symptoms and another diary for the
, which led to THP-1’s cell cycle arrest and differentiation to macrophages, by interacting with hnRNP-U and binding to the promoter of PBOV1. Furthermore, C/EBPβ, NTT, and PBOV1 expression levels within PBMCs were prominently elevated in RA, and were observed to decline after the treatment. Positive correlation between C/EBPβ/NTT/PBOV1 expressions and initial disease activity scores (DAS28) was identified. C/EBPβ expression was also found to be positively correlated with SDAI. These results collectively demonstrate that the C/EBPβ/NTT/PBOV1 axis is significantly