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T Tupitsina, P Slominsky, Y Yufereva, N Perova, D Aronov and S Limborska

References Buraczynska M, Pijanowski Z, Spasiewicz D, Nowicka T, Sodolski T, Widomska - Czekajska T, Ksiazek A. Renin-angiotensin system gene polymorphisms: assessment of the risk of coronary heart disease. Kardiol Pol 2003; 58(1): 1-9. Sekuri C, Cam FS, Ercan E, Tengiz I, Sagcan A, Eser E, Berdeli A, Akin M. Renin-angiotensin system gene polymorphisms and premature coronary heart disease. J Renin Angiotensin Aldosterone Syst 2005; 6(1): 38-42. Gardemann A, Lohre J, Cayci S

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Michael Vogeser and Christoph Seger

strategies to maintain adequacy of circulating 25-hydroxyvitamin D concentrations. Scand J Clin Lab Invest 2012; 72: Suppl 243: 14-23. 36. Liu E, McKeown NM, Pittas AG, Meigs JB, Economos CD, Booth SL, et al. Predicted 25-hydroxyvitamin D score and change in fasting plasma glucose in the Framingham offspring study. Eur J Clin Nutr 2012; 66(1): 139-41. 37. O'Donnell S, Cranney A, Horsley T, Weiler HA, Atkinson SA, Hanley DA, et al. Efficacy of food fortification on serum 25-hydroxyvitamin D concentrations: systematic review. Am J Clin Nutr

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Irina Juhas, Branko Skof, Dejana Popović, Milan Matić and Nenad Janković

, psychosocial and educational status of the student population in the Republic of Serbia« which is financed by Ministry of Education and Science of the Republic of Serbia. Conflict of interest Conflict of interest statement: The authors stated that they have no conflicts of interest regarding the publication of this article. References 1 Lloyd-Jones DM, Wilson PW, Larson MG, Beiser A, Leip EP, D’Agostino RB, et al. Framingham risk score and prediction of lifetime risk for coronary heart disease. Am J Cardiol 2004; 94(1): 20–4. 10.1016/j.amjcard.2004

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Cristina Pop, Gianina C. Crişan, Felicia Loghin and Cristina I. Mogoşan

for short-term risk assessment in patients with dyspnea in the emergency department: the MARKED (Multi mARKer Emergency Dyspnea)-risk score. J Am Coll Cardiol 2012;60(17):1668-77. 73. Wang TJ, Wollert KC, Larson MG, Coglianese E, McCabe EL, Cheng S et al. Prognostic utility of novel biomarkers of cardiovascular stress: the Framingham Heart Study. Circulation 2012;126(13):1596-604. 74. Lu W, Fu C, Chen Y, Lu J, Yao Y, Shen C, Gu Z. Multiplex detection of B-type natriuretic peptide, cardiac troponin I and C-reactive protein with

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Aleksejs Zavorins, Jūlija Voicehovska, Jānis Ķīsis and Aivars Lejnieks

REFERENCES Akin Belli, A., Altun, I. (2017). Assessment of Framingham Risk Score and systemic coronary risk evaluation in rosacea patients, Dermatologica Sinica . Available from: https://doi.org/10.1016/j.dsi.2017.03.006 (accessed 17 May 2017). Alikhan, A., Kurek, L., Feldman, S. R. (2010). The role of tetracyclines in rosacea. Amer. J. Clin. Dermatol., 11 (2), 79–87. Badimon, L., Padró, T., Vilahur, G. (2012). Atherosclerosis, platelets and thrombosis in acute ischaemic heart disease. Eur. Heart J. Acute Cardiovasc. Care, 1 (1), 60

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Füsun Şahin, Ayşe Filiz Koşar, Ayşe Feyza Aslan, Burcu Yiğitbaş and Berat Uslu

the curve) in the differential diagnosis of Group 1 (COPD patients with stable) and Group 2 (COPD patients with exacerbation). B) ROC curve for using RDW (red cell distribution width) levels and AUC value in the differential diagnosis of Group 1 and Group 2. Discussion COPD is considered a systemic disease that is associated with independent risk factors such as diabetes, hypertension, and cardiovascular diseases that have tended to increase in recent years ( 14 ). Since the early 2000s, several studies associating COPD with systemic extra pulmonary

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Theodora Benedek, István Kovács and Imre Benedek

.01.083. 16. Lawall H, Bramlage P, Amann B. Stem cell and progenitor cell therapy in peripheral artery disease. A critical appraisal. Thromb Haemost. 2010;103:696-709. doi: 10.1160/TH09-10-0688. 17. Adam DJ, Beard JD, Cleveland T, Bell J, Bradbury AW, Forbes JF. Bypass versus angioplasty in severe ischaemia of the leg (BASIL): multicentre, randomised controlled trial. Lancet. 2005;366:1925-1934. doi: 10.1016/S0140-6736(05)67704-5. 18. Fowkes FG, Murray GD, Butcher I, et al. Ankle brachial index combined with Framingham Risk Score to predict cardiovascular events

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Liang Hong, Mengqi Luo, Ruixue Wang, Peixin Lu, Wei Lu and Long Lu

threats of gaming the system from attempting to increase the risk score of patients through subjective variables. Kennedy et al. (2013) conducted a retrospective cohort study. In this paper, they identified all Veterans Health Administration (VHA) patients without recent cerebral and cardiovascular (CCV) events treated at twelve facilities from 2003 to 2007 and predicted risk using the Framingham risk score (FRS), logistic regression, generalized additive modeling, and gradient tree boosting. Oztekin et al. (2009) used three different variable selection