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Impact of intestinal helminths on the risks of gastrointestinal haemorrhage and iron deficiency among haemophilia patients in northern Nigeria

References 1 Tantawy AAG. Molecular genetics of hemophilia-A: clinical perspectives. Egypt J Med Hum Genet 2010; 11: 105-14. doi: 10.1016/j.ejmhg.2010.10.005. 2 Nieuwenhuizen L, Schutgens REG, van Asbeck BS, et al. Identification and expression of iron regulators in human synovium: evidence for upregulation in haemophilic arthropathy compared to rheumatoid arthritis, osteoarthritis, and healthy controls. Haemophilia 2013; 19: e218-e227. doi: 10.1111/hae.12208. 3 Lottenberg R, Kitchens CS, Roessler GS, Noyes WD

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Barriers to the implementation of point-of-care ultrasonography by physiotherapists in haemophilia treatment centres in Canada: a modified Delphi approach

REFERENCES 1. Dunn AL. Pathophysiology, diagnosis and prevention of arthropathy in patients with haemophilia. Haemophilia , 2011; 17(4): 571–8. doi: 10.1111/j.1365-2516.2010.02472.x. 2. Srivastava A, Brewer AK, Mauser-Bunschoten EP, et al . Guidelines Working Group on Behalf of the World Federation of Hemophilia. Guidelines for the management of hemophilia. Haemophilia 2013; 19(1): e1–47. doi: 10.1111/j.1365-2516.2012.02909.x. 3. Pettersson H, Ahlberg A, Nilsson IM. A radiologic classification of hemophilic arthropathy. Clin Orthop Relat

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A case study exploring the impact on family life of two genetic conditions – severe haemophilia A and sickle cell disease

.17225/jhp00083). 6. Glenn LD, Lovely RM, Goldsmith JC. Combined sickle cell anemia and mild hemophilia A: successful treatment of hemorrhage with DDAVP. Am J Hematol 1991;37:64. 7. Kumar M, Herring RA. Rare combination of homozygous sickle cell disease (Hb SS) and haemophilia B in a paediatric patient. Br J Haematol 1997;98:780-1. 8. Dhiman P, Chaudhary R, Sudha K. Sickle cell-β thalassemia with concomitant hemophilia A: a rare presentation. Blood Res 2015; 50: 264-7. 9. El Maataoui H, Fahi A, Oukkache B

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US haemophilia centre nurses and advanced practice providers: Demographics, roles/responsibilities, training, educational barriers and employment benefits

References 1. Evatt BL. The natural evolution of haemophilia care: developing and sustaining comprehensive care globally. Haemophilia 2006;12: 13-21. 2. Andoniann AA, Dietrich SL, Whiteman ST. A total program for the patient with hemophilia. I Medical aspects. Journal of American Physical Therapy Association 1966; 46:1268-71. 3. Boone DC. A total program for the patient with hemophilia. II Physical therapy aspects related to orthopedic and neurologic residuals of bleeding. Journal of American Physical Therapy

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A Case of Acquired Hemophilia A with Maxillary Osteitis

factor VIII hemophilia following influenza vaccination. Eur J Clin Pharmacol. 2010;66:1069-70. 5. Collins P, Hirsch S, Baglin TP, et al. Acquired hemophilia A in the United Kingdom: a 2-year national surveillance study by the United Kingdom Haemophilia Centre Doctors’ Organisation. Blood. 2007;109:1870-7. 6. Franchini M, Gandini G, Di Paolantonio T, Mariani G. Acquired hemophilia A: a concise review. Am J Hematol. 2005;80:55-63. 7. Hay CR, Negrier C, Ludlam CA. The treatment of bleeding in acquired hemophiliawith

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Opioid dependence among people with haemophilia in a low-resource tropical setting: prevalence and risk factors in northern Nigeria

REFERENCES 1. Tantawy AAG. Molecular genetics of hemophilia A: clinical perspectives. Egypt J Med Hum Genet 2010; 11: 105–14. doi:10.1016/j.ejmhg.2010.10.005. 2. Ibrahim UA, Ahmed SG. Pathophysiology of bleeding diathesis in haemophilia-A: a sequential and critical appraisal of non-FVIII related haemostatic dysfunctions and their therapeutic implications. Egypt J Med Hum Genet 2018; 19: 285–95. doi:10.1016/j.ejmhg.2018.01.003. 3. Brinkmann T, Kähnert H, Prohaska W, et al. Synthesis of tissue factor pathway inhibitor in human synovial cells

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Use of an innovative syringe pump to deliver bolus rFVIIa for patients with haemophilia and inhibitors undergoing surgery

References 1. Giangrande PL, Wilde JT, Madan B, et al. Consensus protocol for the use of recombinant activated factor VII [eptacog alfa (activated); NovoSeven] in elective orthopaedic surgery in haemophiliac patients with inhibitors. Haemophilia 2009;15(2): 501-8. 2. Nursing and Midwifery Council. Standards for Medicine Management. 2015. Available from: (accessed 24 November 2016). 3. Lee CA, Kessler CM, Varon D

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Diagnosis and management of inhibitors: the need for professional collaboration

References 1. Knoebl P, Marco P, Baudo F, et al. Demographic and clinical data in acquired hemophilia A: results from the European Acquired Haemophilia Registry (EACH2). J Thromb Haemost 2012; 10(4): 622-31. doi: 10.1111/j.1538-7836.2012.04654.x. 2. Baudo F, Collins P, Huth-Kühne A, et al. Management of bleeding in acquired hemophilia A: results from the European Acquired Haemophilia (EACH2) Registry. Blood 2012; 120(1): 39-46. doi: 10.1182/blood-2012-02-408930. 3. Collins P, Baudo F, Knoebl P, et al

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History illustrates the danger that privatisation poses to haemophilia


David Owen was Labour Health Minister 1974-76 and now sits as an independent social democrat in the House of Lords. Before entering Parliament he trained as a medical doctor at St Thomas’s Hospital, London, where he was Clinical Neurologist and Psychiatric Registrar. He has championed the NHS throughout its existence and is now a powerful advocate for its reinstatement to its original purpose. In this extract from his 2014 book The Health of the Nation, NHS in Peril, David Owen sets out the consequences of the 2012 Health and Social Care Act for the haemophilia community.

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Living with an inhibitor: Results from the Study of Haemophilia Experiences, Results and Opportunities in Children and young adults with long-standing inhibitors (the SO-HEROIC study)

References 1 Collins PW, Palmer BP, Chalmers EA, et al; UK Haemophilia Centre Doctors’ Organisation. Factor VIII brand and the incidence of factor VIII inhibitors in previously untreated UK children with severe hemophilia A, 2000-2011. Blood 2014; 124: 3389-97. 2 Peyvandi F, Mannucci PM, Garagiola I, et al. A randomized trial of factor VIII and neutralizing antibodies in hemophilia A. N Engl J Med 2016; 374: 2054-64. 3 Collins P, Chalmers E, Alamelu J, et al. First-line immune tolerance induction for children

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