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Tyrosine kinase inhibitor treatment outcome in a single center cohort of chronic myeloid leukemia patients. The role of the T315I ABL kinase domain mutation

-1066 7. Nicolini FE, Hayette S, Corm S, Bachy E, Bories D, Tulliez M et al. Clinical outcome of 27 imatinib mesylate resistant chronic myelogenous leukemia patients harboring T315I BCR-ABL mutation. The Hematology Journal 2007, 92: 1238-1241 8. Nicolini FE, Mauro MJ, Martinelli G, Kim DW, Soverini S, Muller MC et al. Epidemiologic study on survival of chronic myeloid leukemia and Ph(+) acute lymphoblastic leukemia patients with BCR-ABL T315I mutation. Blood, 2009, 114: 5271-5278. 9. Hughes T, Saglio G, Branford S, Soverini S, Kim DW

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Cytotoxic Effect of Combined Treatment with Ukrain and Methotrexate on Kidney Cells of Green Monkey

vivo preclinical activity against acute lymphoblastic leukaemia and lymphoma. Br J Haematol 2009, 145 , 389-393. 13. Kimura E., Nishimura K., Sakata K., Opa S., Kashiwagi K., Igarashi K.: Methotrexate differentially affects growth of suspension and adherent cells. Int J Biochem Cell Biol 2004, 36 , 814-825. 14. Lanvers-Kaminsky C., Nolting D.M., Köster J., Schröder A., Sandkötter A., Boos J.: In vitro toxicity of Ukrain against human Ewing tumor cell lines. Anticancer Drugs 2006, 17 , 1025-1030. 15. Liepins A

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Gene polymorphisms and diseases in Asians

varies between different ethnic groups. These are explained by genetic variation and susceptibility to disease process. Because variations in the genome occur randomly, certain types of mutation and polymorphism exist in particular ethnic groups. Therefore, when a particular genomic variation and disease association is identified, there is a need to verify usefulness in ethnic groups. Two examples from this issue of the journal illustrate this topic. Acute lymphoblastic leukemia (ALL) is one of the most curable cancers of childhood. The cure is attributed to risk

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Radiation dose from CT scanning: can it be reduced?

; 29: A43-59. 15. Hoffman DA, Lonstein JE, Morin MM, Visscher W, Harris BS 3 rd , Boice JD Jr. Breast cancer in women with scoliosis exposed to multiple diagnostic X-rays. J Natl Cancer Inst. 1989, 81: 1307-12. 16. Doody M, Lonstein JE, Stovall M, Hacker DJ, Luckyanov N, Land CE. Breast cancer mortality after diagnostic radiography: findings from the U.S. Scoliosis Cohort Study. Spine. 2000; 25: 2052-63. 17. Infante-Rivard C. Diagnostic x rays, DNA repair genes and childhood acute lymphoblastic leukemia. Health Phys

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Sensitivity and Reproducibility of Polymerase Chain Reaction Assays for Detection of Human Herpesviruses 6 and 7

immune system: Mechanisms of immunomodulation and viral escape. J. Clin. Virol. 37(Suppl. 1), S4-S10. MacKenzie, J., Gallagher, A., Clayton, R.A., Perry, J., Eden, O.B., Ford, A.M., Greaves, M.F., Jarrett, R.F. (2001). Screening for herpesvirus genomes in common acute lymphoblastic leukemia. Leukemia , 15 (3), 415-421. Murovska, M., Lejniece, S., Kozireva, S., Koulikovska, M., Yin, H., Blomberg, J. (2000). Human retrovirus 5 sequences in peripheral blood cells from patients with B-cell non-Hodgkin's lymphoma. Int

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Burkitt Lymphoma in Elderly Patients

, et al. Treatment of Burkitt's/Burkitt like lymphoma in adolescents and adults: a 20-year experience from the Norwegian Radium Hospital with the use of three successive regimens. Ann Oncol 2004;15:1072-78. PMid:15205201 9. Thomas DA, Faderl S, O'Brien S, et al. Chemioimmunotherapy with hyper-CVAD plus rituximab for the treatment of adult Burkitt and Burkitt-type lymphoma or acute lymphoblastic leukemia. Cancer 2006; 106: 1569-80. PMid:16502413 10. Dixon DO

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A new assay to identify recurrent mutations in acute myeloid leukemia using next-generation sequencing

, Ferrero S, Pepin F, Drandi D, Monitillo L, et al. Next-Generation Sequencing and Real-Time Quantitative PCR for Minimal Residual Disease (MRD) Detection Using the Immunoglobulin Heavy Chain Variable Region: A Methodical Comparison in Acute Lymphoblastic Leukemia (ALL), Mantle Cell Lymphoma (MCL) and Multiple Myeloma (MM). ASH 2012, abstract 788. 13. Schmitt MW, Kennedy S R, Salk JJ, Fox E J, Hiatt JB, Loeb LA. Detection of ultra-rare mutations by next-generation sequencing. Proc Natl Acad Sci USA. 2012 Sep 4;109(36):14508-13. DOI: 10.1073/pnas.1208715109

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Immunoglobulin Heavy Chain Gene Rearrangements in Patients with Gaucher Disease

. Performance of the Sebia CAPILLARYS 2 for detection and immunotyping of serum monoclonal paraproteins. Am J Clin Pathol 2007; 128(2): 293-9. 12. Bossuyt X, Bogaerts A, Schiettekatte G, Blanckaert N. Serum protein electrophoresis and immunofixation by a semiautomated electrophoresis system. Clin Chem 1998; 44(5): 944-9. 13. Green E, McConville CM, Powell JE, Mann JR, Darbyshire PJ, Taylor AM, et al. Clonal diversity of Ig and T-cellreceptor gene rearrangements identifies a subset of childhood B-precursor acute lymphoblastic leukemia with

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Measurement Method of the Width of the Strands of Cut Tobacco Based on Digital Image Processing

.jsv.2013.07.013 15. Eldahshan, K., M. Youssef, E. Masameer, and M.A. Mustafa: Comparison of Segmentation Framework on Digital Microscope Images for Acute Lymphoblastic Leukemia Diagnosis Using RGB and HSV Color Spaces; Biotechnol. Bioeng. 2 (2015) 27–34. DOI: 10.5120/15590-4426 16. Joshi, M.D., A.H. Karode, and S.R. Suralkar: White Blood Cells Segmentation and Classification to Detect Acute Leukemia; Int. J. Emerg. Trends Technol. Comput. Sci. 2 (2013) 147–151. Available at:

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Nutritional Status Associated with Metabolic Syndrome in Middle-School Children in the City of Montes Claros - Mg, Brazil

References Aldhafiri F, Al-Nasser A, Al-Sugair A, Al-Mutairi H, Young D, Reilly JJ. Obesity and Metabolic Syndrome in Adolescent Survivors of Standard Risk Childhood Acute Lymphoblastic Leukemia in Saudi Arabia. Pediatr Blood Cancer, 2012; 59: 133-137 Almeida LS, Freire T. Methodology of Research in Educational Psychology. Braga: Lusografe, 33-39; 2003 Armas MGG, Megías SM, Viveros MM, Bolaños PI, Piñero BV. Prevalence of metabolic syndrome in a population of obese children and adolescents. Endocrinología y

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