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LC-MS Method for Determining Amiodarone and Desethylaminodarone in Rat Plasma Used in Endogenous Overdosing Conditions Following Lipolysis

References 1. Schleifer JW, Sorajja D, Shen WK - Advances in the pharmacologic treatment of ventricular arrhythmias. Expert Opin Pharmacother. 2015;16(17):2637-51. 2. Lu JT, Cai Y, Chen F, Jia WW, Hu ZY, Zhao YS - A Physiologically Based Pharmacokinetic Model of Amiodarone and its Metabolite Desethylamiodarone in Rats: Pooled Analysis of Published Data. Eur J Drug Metab Pharmacokinet. 2016 Dec;41(6):689-703. 3. Roden AC, Camus P - Iatrogenic pulmonary lesions. Semin Diagn Pathol. 2018 Jul;35

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Development and Validation of an UHPLC Method for Ostarine Determination in Dietary Supplements

. European Pharmacopoeia 7th Edition, 2.9.5:265-266. 8. https://www.ema.europa.eu/en/documents/scientific-guideline/ich-q-2-r1-validation-analytical-procedures-text-methodology-step-5_en.pdf 9. Cesbron N, Sydor A, Penot M, Prevost S, Le Bizec B, Dervilly-Pinel G. Analytical strategies to detect enobosarm administration in bovines. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2017; 34(4):632-640. 10. https://cces.ca/canadian-sport-sanction-registry 11. Coss CC, Jones A, Dalton JT. Pharmacokinetic drug interactions of the selective

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Development of a HPLC-UV method for determination of meloxicam in human plasma and pharmaceutical dosage forms

-performance liquid chromatographic estimation method of meloxicam in biological samples. J Chromatogr B Biomed Sci Appl. 2000;738:431-436. 13. Dasandi B, Shivaprakash, Saroj H, Bhat KM. LC determination and pharmacokinetics of meloxicam. J Pharm Biomed Anal. 2002;28:999-1004. 14. Rigato HM, Mendes GD, Borges NC, Moreno RA. Meloxicam determination in human plasma by high-performance liquid chromatography coupled with tandem mass spectrometry (LC-MS-MS) in Brazilian bioequivalence studies. Int J Clin Pharmacol Ther. 2006;44:489-498. 15

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Comparing the Effects of Dexmedetomidine and Midazolam on Sedation in Children with Head Trauma to Perform CT in Emergency Department / Upoređivanje efekata deksmedetomidina i midazolama na sedaciju dece sa povredom glave radi snimanja CT-om na Odeljenju urgentne medicine

. Dexmedetomidine Pharmacokinetics and pharmacodynamics].Anaesthesist 2012;61(12):1059-66. http://dx.doi.org/10.1007/s00101-012-2114-1 7. Fagin A, Palmieri T, Greenhalgh D, Sen S.A comparisonof dexmedetomidine and midazolam for sedation in severe pediatric burn injury.J Burn Care Res. 2012 ;33(6):759-63. http://dx.doi.org/10.1097/BCR.0b013e318254d48e 8. Lam F, Ransom C, Gossett JM, Kelkhoff A, Seib PM, Schmitz ML, Bryant JC, Frazier EA, Gupta P.Safety and efficacy of dexmedetomidine in children with heart failure.Pediatr Cardiol 2013

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Letrozole Determination by Capillary Zone Electrophoresis and UV Spectrophotometry Methods

, et al. - Effect of age and single versus multiple dose pharmacokinetics of letrozole (Femara) in breast cancer patients. Biopharm Drug Dispos. 2001;22:191-197. 14. Letrozole, BCCancer Agency Cancer Drug Manual, Developed: 2001, Page 1-5, Limited revision: 1 May 2006; 1 November 2010, 1 April 2011 (http://www.bccancer.bc.ca/drug-database-site/Drug%20Index/Letrozole_monograph_1April2011.pdf Accessed 14 May 2017) 15. Femara (http://www.accessdata.fda.gov/drugsatfda_docs/nda/97/20726_FEMARA%202.5MG_BIOPHARMR.PDF Accessed 14May 2017

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The Evaluation of Angiotensin-Converting Enzyme Inhibitors in Renal Elimination with Selected Molecular Descriptors

, Ritter JM, Flower RJ, Henderson G. Rang and Dale’s Farmacology 8 th, Elsevier, Churchill Livingstone, 2012. 5. Ruster C, Wolf G. Renin-angiotensin-aldosterone system and progression of renal disease. J Am Soc Nephrol 2006; 17: 2985-2991. 6. Razzetti R, Acerbi D. Pharmacokinetic and pharmacologic properties of delapril, a lipophilic nonsulfhydryl angiotensin converting enzyme inhibitor. Am J Cardiol 1995; 75: 7F-12F. 7. Saruta T, Nishikawa K. Characteristics of a new angiotensin converting enzyme inhibitor: delapril. Am J Hipertens 1991; 2: 23S-28S

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Effect of selective beta-blockade with bisoprolol in the treatment of recent-onset atrial fibrillation

oral loading dose and intavenous administration. Chest 1995;108(2): 355-8. 8. Reiter MJ. Cardiovascular drug class specifi city: beta-blockers. Prog Cardiovasc Dis 2004;47(1): 11-33. 9. Le Coz F, Sauleman P, Poirier JM, et al. Oral pharmacokinetics of bisoprolol in resting and exercising healthy volunteers. J Cardiovasc Pharmacol 1991;18:28-34. 10. Taguchi M, Nozawa T, Igawa A, et al. Pharmacokinetic variability of routinely administered bisoprolol in middle-aged and elderly Japanese patients. Biol Pharm Bull 2005

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Topical Treatment of Infantile Hemangiomas – Where Are We Now? / Topikalni tretman infantilnih hemangioma – gde smo danas?

]. 7. Volotinen M, Hakkola J, Pelkonen O, Vapaatalo H, Maenpaa J. Metabolism of ophthalmic timolol: new aspects of an olddrug. Basic Clin Pharmacol Toxicol 2011;108:297-303. 8. Zimmerman TJ, Kooner KS, Morgan KS. Safety and efficacy of timolol in pediatric glaucoma. Surv Ophthalmol 1983;28:262-4. 9. Kubota K, Yamada T, Kikuchi K, Koyama E, Ishizaki T. Pharmacokinetics and beta-blocking effects of transdermal timolol. Eur J Clin Pharmacol 1993;44:493-5. 10. Guo S, Ni N. Topical treatment for capillary hemangioma of the

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Effect of Atorvastatin and Rosuvastatin on Learning and Memory in Rats with Diazepam-Induced Amnesia

;37(2):294-6. 8. Douma TN, Borre Y, Hendriksen H, et al. Simvastatin improves learning and memory in control but not in olfactory bulbectomized rats. Psychopharmacology 2011;216(4):537-44. 9. Petkov DV. The memory problem - achievements and perspectives. Sofi a: Prof Marin Drinov Publishing House; 1998:23-32 (Bulgarian). 10. Bellosta S, Paoletti R, Corsini A. Safety of statins: focus on clinical pharmacokinetics and drug interactions. Circulation 2004;109(23):III50-7. 11. Malenka RC, Nicoll RA. Long-term potentiation - a decade of

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Acute Poisoning with Dapsone and Olanzapine: Severe Methemoglobinemia and Coma with a Favourable Outcome / Острое Отравление Медикаментами Dapsone И Olanzapine: Тяжёлая Метгемоглобинемия И Кома С Благоприятным Исходом

References 1. Prasad R, Das BP, Singh R, Sharma KK. Dapsone induced methemoglobinemia, sulfhemoglobinemia and hemolytic anemia: a case with a note on treatment strategies. Ind J of Pharm 2002;34:283-5. 2. Zuidema J, Modderman H, Merkus FWHM. Clinical pharmacokinetics of dapsone. Clin Pharmacokinet 1986;11:299-315. 3. Kraemer T, Paul LD, Jochum C, Maurer HH. Acute poisoning with dapsone - a case report. T + K 2002;69(2):80. 4. Smith RP. Toxic resp onses of the blood. In: Klaassen DC, Amdur OM

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